Van Breusegem Frank

Group leader @ Oxidative Stress Signalling

Frank Van Breusegem obtained his Bachelor and Master degree at Ghent University. He is a group leader of the Oxidative Stress Signaling group at the VIB Center for Plant Systems Biology (since 2001); full professor at Ghent University and he recently was elected vice-chair of the Department of Plant Biotechnology and Bioinformatics (Faculty of Sciences, Ghent University). Since his early studies under the supervision of em. Prof. Marc Van Montagu, he focuses on the molecular impact of oxidative stress on plant cells. He obtained his PhD from Ghent University (1997) with work on “Engineering Stress Tolerance in Maize”. Nowadays, the primary objective of the Van Breusegem lab is the identification and functional analysis of regulatory gene and protein networks involved in the oxidative stress response in plants. Ultimately, he aims to translate this knowledge into biotechnological crop efficiency concepts. The lab has played a pioneering role in determining H2O2-dependent molecular and physiological responses in plants. The Van Breusegem lab is internationally recognized mainly because of its successful multi-omics driven approaches that allowed to identify several key targets in the oxidative stress response. Frank Van Breusegem has published more than 150 peer-reviewed publications (Clarivate h-index=59), is a frequent invited speaker and is monitoring editor of the leading plant journal “Plant Physiology”.

Contact information

Office: Technologiepark 71, 9052 Zwijnaarde, Belgium
Office Phone: +32(0)93313920

Social Media


In vivo detection of protein cysteine sulfenylation in plastids.
De Smet, B., Willems, P., Fernandez-Fernandez, AD., Alseekh, S., Fernie, AR., Messens, J., Van Breusegem, F.
Damage on plants activates Ca2+-dependent metacaspases for release of immunomodulatory peptides
Hander, T., Fernández-Fernández, ÁD., Kumpf, RP., Willems, P., Schatowitz, H., Rombaut, D., Staes, A., Nolf, J., Pottie, R., Yao, P., Gonçalves, A., Pavie, B., Boller, T., Gevaert, K., Van Breusegem, F., Bartels, S., Stael, S.
The Plant PTM Viewer, a central resource for exploring plant protein modifications.
Willems, P., Horne, A., Van Parys, T., Goormachtig, S., De Smet, I., Botzki, A., Van Breusegem, F., Gevaert, K.
Mining for protein S-sulfenylation in Arabidopsis uncovers redox-sensitive sites.
Huang, J., Willems, P., Wei, B., Tian, C., Ferreira, R., Bodra, N., Martinez Gache, S.A., Wahni, K., Liu, K., Vertommen, D., Gevaert, K., Carroll, KS., Van Montagu, M., Yang, J., Van Breusegem, F., Messens, J.
Molecular priming as an approach to induce tolerance against abiotic and oxidative stresses in crop plants.
Kerchev, P., van der Meer, T., Sujeeth, N., Verlee, A., Stevens, CV., Van Breusegem, F., Gechev, T.