M'Hamdi Amna

M'Hamdi Amna - Staff scientist @ Oxidative Stress Signalling

Expertise: ROS metabolism and oxidative stress signalling

Amna Mhamdi obtained her Master's degree in Plant Physiology and Biotechnology from Tunis El Manar University (Tunisia) in 2006. In 2007, she started her PhD in the group of Graham Noctor at the Université de Paris Sud (France), studying the role of enzymes involved in glutathione and NADPH reduction in oxidative stress signalling. After obtaining her PhD in 2010, she stayed in the same laboratory and continued as a postdoctoral researcher. From 2016, she joined the oxidative stress signalling group led by Frank Van Breusegem at PSB (Belgium) to study the photorespiratory hydrogen peroxide signalling mechanisms and cysteine oxidation events that occur during plant responses to stress. Since 2023, Amna has been working as a Staff Scientist at VIB-Belgium, Frank Van Breusegem group, with a special focus on understanding the role of redox regulation of transcription complexes and translating key findings observed in Arabidopsis to crop plants. To address research questions in the field of redox and oxidative signalling, Amna is using an integrative approach involving genetics and transcriptomic, proteomic as well as metabolomic profiling.

48. Cytosolic Monodehydroascorbate Reductase 2 Promotes Oxidative Stress Signaling in Arabidopsis

Dongdong Xu, Lug Trémulot, Zheng Yang, Amna Mhamdi, Gilles Châtel‐Innocenti, Laura Mathieu, Christophe Espinasse, Frank Van Breusegem, Hélène Vanacker, Emmanuelle Issakidis‐Bourguet, Graham Noctor

(2025) - Plant, Cell & Environment

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47. The nuclear sulfenome ofArabidopsis: spotlight on histone acetyltransferase GCN5 regulation through functional thiols

Barbara De Smet, Xi Yang, Zuzana Plskova, Carmen Castell, Alvaro Fernandez-Fernandez, Avilien Dard, Amna Mhamdi, Didier Vertommen, Kai Xun Chan, Sébastien Pyr dit Ruys, Joris Messens, Pavel I. Kerchev, Frank Van Breusegem

(2024) -

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46. Redox regulation of gene expression: proteomics reveals multiple previously undescribed redox-sensitive cysteines in transcription complexes and chromatin modifiers

Avilien Dard, Frank Van Breusegem, Amna Mhamdi, Graham Noctor

(2024) - Journal of Experimental Botany

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45. Glutathione: a key modulator of plant defence and metabolism through multiple mechanisms

Graham Noctor, Mathias Cohen, Lug Trémulot, Gilles Châtel-Innocenti, Frank Van Breusegem, Amna Mhamdi, Karl-Josef Dietz

(2024) - Journal of Experimental Botany

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44. The Arabidopsis mediator complex subunit 8 regulates oxidative stress responses

Huaming He, Jordi Denecker, Katrien Van Der Kelen, Patrick Willems, Robin Pottie, Su Yin Phua, Matthew A Hannah, Didier Vertommen, Frank Van Breusegem, Amna Mhamdi

(2021) - The Plant Cell

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43. On the move: redox-dependent protein relocation in plants

Christine H Foyer, Alison Baker, Megan Wright, Imogen A Sparkes, Amna Mhamdi, Jos H M Schippers, Frank Van Breusegem, Karl-Josef Dietz

(2020) - Journal of Experimental Botany

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42. The Protein Phosphatase PP2A-B′γ Takes Control over Salicylic Acid to Suppress Defense and Premature Senescence

Amna Mhamdi

(2020) - Plant Physiology

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41. What Are the Roles for Dehydroascorbate Reductases and Glutathione in Sustaining Ascorbate Accumulation?

Elisa Dell’Aglio, Amna Mhamdi

(2020) - Plant Physiology

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40. MYB30 Links the Reactive Oxygen Species Wave to Systemic Acclimation

Amna Mhamdi

(2020) - Plant Physiology

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39. To Grow or Not to Grow: Specific Lipoxygenases Control Wound-Induced Growth Restriction

Amna Mhamdi

(2020) - Plant Physiology

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38. Here, There, and Everywhere: Plastid- and Nuclear-Localized WHIRLY1 Regulates Salicylic Acid Homeostasis during Developmental Senescence

Amna Mhamdi

(2020) - Plant Physiology

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37. Analysis of catalase mutants underscores the essential role of CATALASE2 for plant growth and day length‐dependent oxidative signalling

Zheng Yang, Amna Mhamdi, Graham Noctor

(2019) - Plant, Cell & Environment

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36. Another gun Dismantled: ABSCISIC ACID INSENSITIVE4 Is Not a Target of Retrograde Signaling

Amna Mhamdi, Charlotte M.M. Gommers

(2019) - Plant Physiology

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35. The Immune Redoxome: Effector-Triggered Immunity Switches Cysteine Oxidation Profiles

Amna Mhamdi

(2019) - Plant Physiology

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34. A Novel Specialized Immune Player: BSK5 Is Required for Restricting Pathogen Progression

Amna Mhamdi

(2019) - Plant Physiology

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33. Keep Sugar Away to Stay Active: Glycosylation of Methyl Salicylate Shuts Down Systemic Signaling

Amna Mhamdi

(2019) - Plant Physiology

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32. NPR1 Has Everything under Control

Amna Mhamdi

(2019) - Plant Physiology

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31. Reactive oxygen species in plant development

Amna Mhamdi, Frank Van Breusegem

(2018) - Development

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30. Managing Competing Interests: Partitioning S between Glutathione and Protein Synthesis

Amna Mhamdi

(2018) - Plant Physiology

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29. Redox-dependent control of nuclear transcription in plants

Huaming He, Frank Van Breusegem, Amna Mhamdi

(2018) - Journal of Experimental Botany

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28. Highlighting the Fast Signals that Establish Remote Metabolite Profiles

Amna Mhamdi, Scott Hayes

(2018) - Plant Physiology

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27. Climate Change, CO2, and Defense: The Metabolic, Redox, and Signaling Perspectives.

Noctor G, Mhamdi A

(2017) - Trends in plant science

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26. Measurement of Transcripts Associated with Photorespiration and Related Redox Signaling.

Mhamdi A, Kerchev PI, Willems P, Noctor G, Van Breusegem F

(2017) - Methods in molecular biology (Clifton, N.J.)

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25. Cytosolic and Chloroplastic DHARs Cooperate in Oxidative Stress-Driven Activation of the Salicylic Acid Pathway

Marie-Sylviane Rahantaniaina, Shengchun Li, Gilles Chatel-Innocenti, Andrée Tuzet, Emmanuelle Issakidis-Bourguet, Amna Mhamdi, Graham Noctor

(2017) - Plant Physiology

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24. Glutathione oxidation in response to intracellular H2O2: Key but overlapping roles for dehydroascorbate reductases.

Rahantaniaina MS, Li S, Chatel-Innocenti G, Tuzet A, Mhamdi A, Vanacker H, Noctor G

(2017) - Plant signaling & behavior

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23. SHORT-ROOT Deficiency Alleviates the Cell Death Phenotype of the Arabidopsis catalase2 Mutant under Photorespiration-Promoting Conditions

Cezary Waszczak, Pavel I. Kerchev, Per Mühlenbock, Frank A. Hoeberichts, Katrien Van Der Kelen, Amna Mhamdi, Patrick Willems, Jordi Denecker, Robert P. Kumpf, Graham Noctor, Joris Messens, Frank Van Breusegem

(2016) - The Plant Cell

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22. The ROS Wheel: Refining ROS Transcriptional Footprints

Patrick Willems, Amna Mhamdi, Simon Stael, Veronique Storme, Pavel Kerchev, Graham Noctor, Kris Gevaert, Frank Van Breusegem

(2016) - Plant Physiology

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21. High CO2 Primes Plant Biotic Stress Defences through Redox-Linked Pathways.

Mhamdi A, Noctor G

(2016) - Plant physiology

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20. Oxidative stress and antioxidative systems: recipes for successful data collection and interpretation.

Noctor G, Mhamdi A, Foyer CH

(2016) - Plant, cell & environment

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19. Analysis of the roles of the Arabidopsis peroxisomal isocitrate dehydrogenase in leaf metabolism and oxidative stress

Mhamdi, Amna, Noctor, Graham

(2015) - Environmental and Experimental Botany

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18. The metabolomics of oxidative stress

Noctor, Graham, Lelarge-Trouverie, Caroline, Mhamdi, Amna

(2015) - Phytochemistry

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17. The protein phosphatase subunit PP2A-B 'gamma is required to suppress day length-dependent pathogenesis responses triggered by intracellular oxidative stress

Li, Shengchun, Mhamdi, Amna, Trotta, Andrea, Kangasjaervi, Saijaliisa, Noctor, Graham

(2014) - New Phytologist

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16. The Roles of Reactive Oxygen Metabolism in Drought: Not So Cut and Dried

Noctor, Graham, Mhamdi, Amna, Foyer, Christine H.

(2014) - Plant Physiology

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15. Glutathione and NADPH in plant responses to H2O2.

Noctor G, Mhamdi A

(2014) - Free radical biology & medicine

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14. Analysis of cytosolic isocitrate dehydrogenase and glutathione reductase 1 in photoperiod-influenced responses to ozone using Arabidopsis knockout mutants

Dghim, Ata Allah, Mhamdi, Amna, Vaultier, Marie-Noelle, Hasenfratz-Sauder, Marie-Paule, Le Thiec, Didier, Dizengremel, Pierre, Noctor, Graham, Jolivet, Yves

(2013) - Plant Cell and Environment

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13. Analysis of knockout mutants suggests that Arabidopsis NADP-MALIC ENZYME2 does not play an essential role in responses to oxidative stress of intracellular or extracellular origin

Li, Shengchun, Mhamdi, Amna, Clement, Cyndie, Jolivet, Yves, Noctor, Graham

(2013) - Journal of Experimental Botany

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12. Functional Analysis of Arabidopsis Mutants Points to Novel Roles for Glutathione in Coupling H2O2 to Activation of Salicylic Acid Accumulation and Signaling

Han, Yi, Chaouch, Sejir, Mhamdi, Amna, Queval, Guillaume, Zechmann, Bernd, Noctor, Graham

(2013) - Antioxidants & Redox Signaling

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11. Glutathione-dependent phytohormone responses: teasing apart signaling and antioxidant functions.

Mhamdi, Amna, Han, Yi, Noctor, Graham

(2013) - Plant signaling & behavior

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10. Missing links in understanding redox signaling via thiol/disulfide modulation: how is glutathione oxidized in plants?

Rahantaniaina, Marie-Sylviane, Tuzet, Andree, Mhamdi, Amna, Noctor, Graham

(2013) - Frontiers in Plant Science

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9. Regulating the Redox Gatekeeper: Vacuolar Sequestration Puts Glutathione Disulfide in Its Place

Noctor, Graham, Mhamdi, Amna, Queval, Guillaume, Foyer, Christine H.

(2013) - Plant Physiology

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8. Regulation of basal and oxidative stress-triggered jasmonic acid-related gene expression by glutathione

Han, Yi, Mhamdi, Amna, Chaouch, Sejir, Noctor, Graham

(2013) - Plant Cell and Environment

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7. Glutathione in plants: an integrated overview

Noctor, Graham, Mhamdi, Amna, Chaouch, Sejir, Han, Yi, Neukermans, Jenny, Marquez-Garcia, Belen, Queval, Guillaume, Foyer, Christine H.

(2012) - Plant Cell and Environment

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6. Plant catalases: Peroxisomal redox guardians

Mhamdi, Amna, Noctor, Graham, Baker, Alison

(2012) - Archives of Biochemistry and Biophysics

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5. Glutathione.

Noctor, Graham, Queval, Guillaume, Mhamdi, Amna, Chaouch, Sejir, Foyer, Christine H

(2011) - The Arabidopsis book / American Society of Plant Biologists

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4. Arabidopsis GLUTATHIONE REDUCTASE1 Plays a Crucial Role in Leaf Responses to Intracellular Hydrogen Peroxide and in Ensuring Appropriate Gene Expression through Both Salicylic Acid and Jasmonic Acid Signaling Pathways

Mhamdi, Amna, Hager, Jutta, Chaouch, Sejir, Queval, Guillaume, Han, Yi, Taconnat, Ludivine, Saindrenan, Patrick, Gouia, Houda, Issakidis-Bourguet, Emmanuelle, Renou, Jean-Pierre, Noctor, Graham

(2010) - Plant Physiology

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3. Catalase function in plants: a focus on Arabidopsis mutants as stress-mimic models

Mhamdi, Amna, Queval, Guillaume, Chaouch, Sejir, Vanderauwera, Sandy, Van Breusegem, Frank, Noctor, Graham

(2010) - Journal of Experimental Botany

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2. Cytosolic NADP-dependent isocitrate dehydrogenase contributes to redox homeostasis and the regulation of pathogen responses in Arabidopsis leaves

Mhamdi, Amna, Mauve, Caroline, Gouia, Houda, Saindrenan, Patrick, Hodges, Michael, Noctor, Graham

(2010) - Plant Cell and Environment

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1. Peroxisomal Hydrogen Peroxide Is Coupled to Biotic Defense Responses by ISOCHORISMATE SYNTHASE1 in a Daylength-Related Manner

Chaouch, Sejir, Queval, Guillaume, Vanderauwera, Sandy, Mhamdi, Amna, Vandorpe, Michael, Langlois-Meurinne, Mathilde, Van Breusegem, Frank, Saindrenan, Patrick, Noctor, Graham

(2010) - Plant Physiology

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