"From protein-protein to human-machine interactions: The rise of networks in biology and medicine"

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Thursday 14 June 2018, 11:00 - 12:30


From protein interactions to signal transduction, from metabolism to the nervous system: Virtually all processes in health and disease rely on the careful coordination and orchestration of a large number of diverse individual components ranging from molecules to cells and entire organs. Tools and concepts from network science can help disentangle this enormous complexity within and across different levels of biological organization and provide a framework for understanding disease phenomena in a holistic fashion. In my presentation I will highlight recent advancements in the emerging field of ‘network medicine’ and discuss exciting future directions. First, I will show how molecular networks can be understood as maps in which diseases correspond to perturbed neighborhoods. Second, I will introduce a network-based approach to investigate the basic principles that underlie drug-drug interactions. Lastly, I will present our vision of a virtual reality platform for the next generation of data integration and exploration: For the first time, we will showcase our VR ‘network-holodeck’ prototype that enables researchers to inspect large molecular networks enriched with various genomic data. There will also be an opportunity for a hands-on experience of our VR prototype.

Location Jozef Schell Seminar Room
Contact Dr Jörg Menche
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences (member of EULife)