“The elongation phase of RNA polymerase II transcription in Arabidopsis and its coordination with co-transcriptional processes”

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Wednesday 10 January 2018, 16:00 - 17:30

 
ABSTRACT

Transcriptional elongation by RNA polymerase II (RNAPII) is a dynamic and highly regulated step of the transcription cycle. Accordingly, multiple so-called transcript elongation factors (including modulators of RNAPII activity, histone chaperones, histone modifiers) were identified that control the synthesis of mRNAs. Proteomic studies demonstrated that several of these factors form with RNAPII a transcript elongation complex in Arabidopsis. In addition, a variety of pre-mRNA splicing and polyadenylation factor were found to associate with this complex. Therefore, the RNAPII elongation complex serves as a platform coordinating ongoing transcription with mRNA processing and export.

Location Jozef Schell Seminar Room
Contact Prof Klaus Grasser
Department of Cell Biology and Plant Biochemistry
University of Regensburg
GERMANY