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"Hormone-mediated inactivation of a plant E3 ubiquitin ligase complex"

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Wednesday 23 August 2017, 11:00 - 12:30


Phytohormone abscisic acid (ABA) regulates key processes in plants relative to seed germination, plant development and responses to important environmental stresses, such as drought, salinity and extreme temperatures. ABA perception is tightly controlled by the ubiquitin proteasome system. CRL4-CDDD E3 ubiquitin ligases target ABA receptors of the PYR/PYL/RCAR (pyrabactin resistance/pyrabactin resistance-like/regulatory components of ABA) family, triggering their ubiquitination and proteasomal degradation. Therefore, CRL4-CDDD complexes function as repressors of ABA-mediated stress responses. On the contrary, ABA treatment attenuates receptor degradation although the precise molecular details of this mechanism have remained unknown. In this seminar, our most recent data on the regulatory process underlying ABA-mediated protection of PYR/PYL/RCAR receptors, by CRL4-CDDD E3 ubiquitin ligases inactivation, will be shown.

Location Jozef Schell Seminar Room
Contact Dr Vicente Rubio
Department of Plant Molecular Genetics
Centro Nacional de Biotecnología-CSIC