lapauCRISPR technology is revolutionizing plant breeding. Due to high efficiency and simple design, CRISPR has brought genome engineering (GE) in reach of most academic labs, small and medium enterprises. Plant transformation is however a major bottleneck in plant gene editing. The Crop Genome Engineering Facility (CGEF) operates a maize transformation platform that can be accessed by academic labs and by companies. In addition, we perform cutting-edge research to facilitate plant regeneration and to improve CRISPR delivery.

Plant regeneration is a bottleneck for transformation and gene editing. We are investigating the use and function of morphogenic regulators in maize to increase transformation efficiency.

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Currently gene editing relies primarily on Agrobacterium for delivery. We are “engineering the engineer” in order to develop new strains with improved properties for plant transformation.

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