Pauwels Laurens

Staff scientist @ Crop Genome Engineering Facility

I am leading the Crop Genome Engineering Facility at VIB. My mission is to make gene editing in crops more accessible for researchers.

My career started with a  PhD in the Alain Goossens lab at VIB-UGent I used protein-protein interaction mapping and reverse genetics to unravel jasmonate transcriptional regulation in Arabidopsis. After a stay at UC Davis with Judy Callis working on protein ubiquitination and degradation, I returned to the Goossens lab to continue this research line, and set up CRISPR/Cas9 gene editing in the lab for yeast, Arabidopsis and tomato. In 2017, I started at VIB as a staff scientist and manager of the Crop Genome Engineering Facility.

The research in my group currently focuses on improving methods for CRISPR delivery and plant regeneration within maize. Other projects include engineering of Agrobacterium tumefaciens, combining haploid induction and genome editing, gene editing of other species such as wheat and banana.

Contact information

Office: Technologiepark 71, 9052 Zwijnaarde, Belgium
Office Phone: +32(0)93313971

Social Media


NINJA connects the co-repressor TOPLESS to jasmonate signalling.
Pauwels, L., Barbero, GF., Geerinck, J., Tilleman, S., Grunewald, W., Pérez, AC., Chico, JM., Bossche, RV., Sewell, J., Gil, E., García-Casado, G., Witters, E., Inzé, D., Long, JA., De Jaeger, G., Solano, R., Goossens, A.
Lessons from Domestication: Targeting Cis-Regulatory Elements for Crop Improvement.
Swinnen, G., Goossens, A., Pauwels, L.
The transcriptional repressor complex FRS7-FRS12 regulates flowering time and growth in Arabidopsis.
Ritter, A., Iñigo, S., Fernández-Calvo, P., Heyndrickx, KS., Dhondt, S., Shi, H., De Milde, L., Vanden Bossche, R., De Clercq, R., Eeckhout, D., Ron, M., Somers, DE., Inzé, D., Gevaert, K., De Jaeger, G., Vandepoele, K., Pauwels, L., Goossens, A.
A Dual sgRNA Approach for Functional Genomics in Arabidopsis thaliana.
Pauwels, L., De Clercq, R., Goossens, J., Iñigo, S., Williams, C., Ron, M., Britt, A., Goossens, A.
Selective auxin agonists induce specific AUX/IAA protein degradation to modulate plant development.
Vain, T., Raggi, S., Ferro, N., Barange, DK., Kieffer, M., Ma, Q., Doyle, SM., Thelander, M., Pařízková, B., Novák, O., Ismail, A., Enquist, PA., Rigal, A., Łangowska, M., Harborough, SR., Zhang, Y., Ljung, K., Callis, J., Almqvist, F., Kepinski, S., Estelle, M., Pauwels, L., Robert, S.