The regulation of transcription is a main component in the control of gene expression. Yet, little is known about the overall structure of the Arabidopsis transcriptional network. In addition to the generation and mining of large transcript profile compendia, tools are required to functionally test at a large scale the activity of the genome cis-regulatory elements and the associated proteins that control gene transcription. The SAP consortium aims at providing such tools for the Systematic analysis of Arabidopsis Promoters and includes laboratories in seven European countries.
The initial resource the consortium has produced is a collection of genomic amplicons carrying intergenic regions upstream of ca. 20,000 Arabidopsis protein-coding genes. This SAP promoterome collection is available upon request and additional details about the structure of the promoter amplicons are available on line.
To refer to materials created within the SAP initiative and to related results, please cite the following article:
Benhamed, M., Martin-Magniette, M.-L., Taconnat. L., Bitton, F., Servet, C., De Clercq, C., De Meyer, B., Buyschaert, C., Rombauts, S., Villarroel, R., Aubourg, S., Beynon, J., Bhalerao, R.P., Coupland, G., Gruissem, W., Menke, F., Weisshaar, B., Renou, J.-P., Zhou, D.-X. and Hilson, P. (2008) Genome-scale Arabidopsis promoter array identifies targets of the histone acetyltransferase GCN5. Plant J. 56(3):493-504. PubMed