anpic2Prof. Ann Depicker coordinates the Plant-made Antibodies and Immunogens group. Plant-based systems provide an attractive alternative for the production of valuable recombinant proteins as compared to mammalian and bacterial production platforms. Besides applying the eukaryotic processing machinery, they offer several advantages, including low production costs, the lack of mammalian pathogen contaminants, and the ease of agricultural scale-up. Different plant tissues can be used for the production of recombinant proteins, of which leaves and seeds are very promising bioreactors. Seeds allow recombinant proteins to stably accumulate at a relatively high concentration and they can be stored at room temperature for long periods of time. Both these factors further enable convenient downstream processing. Besides, antibodies and immunogens in the seed matrix can be used for oral delivery.

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Icon 3Antibodies are excellent tools for protein research. Provided they have the desired affinity, specificity and functionality, they allow elucidating different aspects of the protein of interest. 

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