Eeckhout Dominique

Eeckhout Dominique - INTERACTOMICS FACILITY/Platform coordinator
Joined the group in 1996

59. Adaptor protein complex interaction map in Arabidopsis identifies P34 as a common stability regulator

Peng Wang, Wei Siao, Xiuyang Zhao, Deepanksha Arora, Ren Wang, Dominique Eeckhout, Jelle Van Leene, Rahul Kumar, Anaxi Houbaert, Nancy De Winne, Evelien Mylle, Michael Vandorpe, Ruud A. Korver, Christa Testerink, Kris Gevaert, Steffen Vanneste, Geert De Jaeger, Daniël Van Damme, Eugenia Russinova

(2023) - Nature Plants

DOI
58. Phase separation-based visualization of protein–protein interactions and kinase activities in plants

Alaeddine Safi, Wouter Smagghe, Amanda Gonçalves, Qing Wang, Ke Xu, Ana Ibis Fernandez, Benjamin Cappe, Franck B Riquet, Evelien Mylle, Dominique Eeckhout, Nancy De Winne, Eveline Van De Slijke, Freya Persyn, Geert Persiau, Daniël Van Damme, Danny Geelen, Geert De Jaeger, Tom Beeckman, Jelle Van Leene, Steffen Vanneste

(2023) - The Plant Cell

DOI
57. SAMBA controls cell division rate during maize development

Pan Gong, Michiel Bontinck, Kirin Demuynck, Jolien De Block, Kris Gevaert, Dominique Eeckhout, Geert Persiau, Stijn Aesaert, Griet Coussens, Mieke Van Lijsebettens, Laurens Pauwels, Geert De Jaeger, Dirk Inzé, Hilde Nelissen

(2022) - Plant Physiology

DOI
56. Correction to: Establishment of Proximity-Dependent Biotinylation Approaches in Different Plant Model Systems

Deepanksha Arora, Nikolaj B Abel, Chen Liu, Petra Van Damme, Klaas Yperman, Dominique Eeckhout, Lam Dai Vu, Jie Wang, Anna Tornkvist, Francis Impens, Barbara Korbei, Jelle Van Leene, Alain Goossens, Geert De Jaeger, Thomas Ott, Panagiotis Nikolaou Moschou, Daniël Van Damme

(2022) - The Plant Cell

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55. ROPGAP-dependent interaction between brassinosteroid and ROP2-GTPase signaling controls pavement cell shape in Arabidopsis

Cheng Zhang, Theresa Lauster, Wenxin Tang, Anaxi Houbaert, Shanshuo Zhu, Dominique Eeckhout, Ive De Smet, Geert De Jaeger, Thomas B. Jacobs, Tongda Xu, Sabine Müller, Eugenia Russinova

(2022) - Current Biology

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54. Proteomic characterization of isolated Arabidopsis clathrin-coated vesicles reveals evolutionarily conserved and plant-specific components

Dana A Dahhan, Gregory D Reynolds, Jessica J Cárdenas, Dominique Eeckhout, Alexander Johnson, Klaas Yperman, Walter A Kaufmann, Nou Vang, Xu Yan, Inhwan Hwang, Antje Heese, Geert De Jaeger, Jiří Friml, Daniël Van Damme, Jianwei Pan, Sebastian Y Bednarek

(2022) - The Plant Cell

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53. Proteomic Characterization of Isolated Arabidopsis Clathrin-Coated Vesicles Reveals Evolutionarily Conserved and Plant Specific Components

Dana A. Dahhan, Gregory D. Reynolds, Jessica J. Cárdenas, Dominique Eeckhout, Alexander Johnson, Klaas Yperman, Walter A. Kaufmann, Nou Vang, Xu Yan, Inhwan Hwang, Antje Heese, Geert De Jaeger, Jiri Friml, Daniel Van Damme, Jianwei Pan, Sebastian Y. Bednarek

(2021) -

DOI
52. Distinct EH domains of the endocytic TPLATE complex confer lipid and protein binding

Klaas Yperman, Anna C. Papageorgiou, Romain Merceron, Steven De Munck, Yehudi Bloch, Dominique Eeckhout, Qihang Jiang, Pieter Tack, Rosa Grigoryan, Thomas Evangelidis, Jelle Van Leene, Laszlo Vincze, Peter Vandenabeele, Frank Vanhaecke, Martin Potocký, Geert De Jaeger, Savvas N. Savvides, Konstantinos Tripsianes, Roman Pleskot, Daniel Van Damme

(2021) - Nature Communications

DOI
51. Molecular architecture of the endocytic TPLATE complex

Klaas Yperman, Jie Wang, Dominique Eeckhout, Joanna Winkler, Lam Dai Vu, Michael Vandorpe, Peter Grones, Evelien Mylle, Michael Kraus, Romain Merceron, Jonah Nolf, Eliana Mor, Pieter De Bruyn, Remy Loris, Martin Potocký, Savvas N. Savvides, Bert De Rybel, Geert De Jaeger, Daniël Van Damme, Roman Pleskot

(2021) - Science Advances

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50. Conditional destabilization of the TPLATE complex impairs endocytic internalization

Jie Wang, Klaas Yperman, Peter Grones, Qihang Jiang, Jonathan Dragwidge, Evelien Mylle, Eliana Mor, Jonah Nolf, Dominique Eeckhout, Geert De Jaeger, Bert De Rybel, Roman Pleskot, Daniel Van Damme

(2021) - Proceedings of the National Academy of Sciences

DOI
49. SAMBA controls the rate of cell division in maize development through APC/C interaction

Pan Gong, Michiel Bontinck, Kirin Demuynck, Jolien De Block, Kris Gevaert, Dominique Eeckhout, Geert Persiau, Stijn Aesaert, Griet Coussens, Mieke Van Lijsebettens, Laurens Pauwels, Geert De Jaeger, Dirk Inzé, Hilde Nelissen

(2021) -

DOI
48. Arabidopsis casein kinase 2 triggers stem cell exhaustion under Al toxicity and phosphate deficiency through activating the DNA damage response pathway

Pengliang Wei, Manon Demulder, Pascale David, Thomas Eekhout, Kaoru Okamoto Yoshiyama, Long Nguyen, Ilse Vercauteren, Dominique Eeckhout, Margot Galle, Geert De Jaeger, Paul Larsen, Dominique Audenaert, Thierry Desnos, Laurent Nussaume, Remy Loris, Lieven De Veylder

(2021) - The Plant Cell

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47. FRS7 and FRS12 recruit NINJA to regulate expression of glucosinolate biosynthesis genes

Patricia Fernández‐Calvo, Sabrina Iñigo, Gaétan Glauser, Robin Vanden Bossche, Michelle Tang, Baohua Li, Rebecca De Clercq, Astrid Nagels Durand, Dominique Eeckhout, Kris Gevaert, Geert De Jaeger, Siobhan M. Brady, Daniel J. Kliebenstein, Laurens Pauwels, Alain Goossens, Andrés Ritter

(2020) - New Phytologist

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46. UBP12 and UBP13 negatively regulate the activity of the ubiquitin-dependent peptidases DA1, DAR1 and DAR2.

Vanhaeren H, Chen Y, Vermeersch M, De Milde L, De Vleeschhauwer V, Natran A, Persiau G, Eeckhout D, De Jaeger G, Gevaert K, Inzé D

(2020) - eLife

DOI
45. Distinct EH domains of the endocytic TPLATE complex confer lipid and protein binding

Klaas Yperman, Anna C. Papageorgiou, Romain Merceron, Steven De Munck, Yehudi Bloch, Dominique Eeckhout, Pieter Tack, Thomas Evangelidis, Jelle Van Leene, Laszlo Vincze, Peter Vandenabeele, Martin Potocký, Geert De Jaeger, Savvas N. Savvides, Konstantinos Tripsianes, Roman Pleskot, Daniel Van Damme

(2020) -

DOI
44. The TPLATE subunit is essential for structural assembly of the endocytic TSET complex

Klaas Yperman, Jie Wang, Dominique Eeckhout, Joanna Winkler, Lam Dai Vu, Michael Vandorpe, Peter Grones, Evelien Mylle, Michael Kraus, Romain Merceron, Jonah Nolf, Eliana Mor, Pieter De Bruyn, Remy Loris, Martin Potocký, Savvas N. Savvides, Bert De Rybel, Geert De Jaeger, Daniel Van Damme, Roman Pleskot

(2020) -

DOI
43. Establishment of Proximity-Dependent Biotinylation Approaches in Different Plant Model Systems

Deepanksha Arora, Nikolaj B. Abel, Chen Liu, Petra Van Damme, Klaas Yperman, Dominique Eeckhout, Lam Dai Vu, Jie Wang, Anna Tornkvist, Francis Impens, Barbara Korbei, Jelle Van Leene, Alain Goossens, Geert De Jaeger, Thomas Ott, Panagiotis Nikolaou Moschou, Daniël Van Damme

(2020) - The Plant Cell

DOI
42. Establishment of Proximity-dependent Biotinylation Approaches in Different Plant Model Systems

Arora D, B. Abel N, Liu C, Van Damme P, Yperman K, Dai Vu L, Wang J, Tornkvist A, Impens F, Korbei B, Eeckhout D, Van Leene J, Goossens A, Van Damme D

(2019) -

DOI
41. TPX2-LIKE PROTEIN3 Is the Primary Activator of α-Aurora Kinases and Is Essential for Embryogenesis.

Boruc J, Deng X, Mylle E, Besbrugge N, Van Durme M, Demidov D, Tomaštíková ED, Tan TC, Vandorpe M, Eeckhout D, Beeckman T, Nowack MK, De Jaeger G, Van Damme D

(2019) - Plant physiology

DOI
40. Capturing the phosphorylation and protein interaction landscape of the plant TOR kinase.

Van Leene J, Han C, Gadeyne A, Eeckhout D, Matthijs C, Cannoot B, De Winne N, Persiau G, Van De Slijke E, Van de Cotte B, Stes E, Van Bel M, De Jaeger G

(2019) - Nature plants

DOI
39. Recent Trends in Plant Protein Complex Analysis in a Developmental Context.

Bontinck M, Van Leene J, Gadeyne A, De Rybel B, Eeckhout D, Nelissen H, De Jaeger G

(2018) - Frontiers in Plant Science

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38. DET1-mediated degradation of a SAGA-like deubiquitination module controls H2Bub homeostasis

Nassrallah A, Rougée M, Bourbousse C, Drevensek S, Fonseca S, Iniesto E, Ait-Mohamed O, Deton-Cabanillas A, Zabulonb G, Ahmed I, Stroebel D, Barneche F

(2018) -

DOI
37. GSyellow, a Multifaceted Tag for Functional Protein Analysis in Monocot and Dicot Plants.

Besbrugge N, Van Leene J, Eeckhout D, Cannoot B, Kulkarni SR, De Winne N, Persiau G, Van De Slijke E, Bontinck M, Aesaert S, Impens F, Gevaert K, De Jaeger G

(2018) - Plant physiology

DOI
36. POLAR-guided signalling complex assembly and localization drive asymmetric cell division.

Houbaert A, Zhang C, Tiwari M, Wang K, de Marcos Serrano A, Savatin DV, Urs MJ, Zhiponova MK, Gudesblat GE, Vanhoutte I, Eeckhout D, Boeren S, Russinova E

(2018) - Nature

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35. DET1-mediated degradation of a SAGA-like deubiquitination module controls H2Bub homeostasis.

Nassrallah A, Rougée M, Bourbousse C, Drevensek S, Fonseca S, Iniesto E, Ait-Mohamed O, Deton-Cabanillas AF, Zabulon G, Ahmed I, Stroebel D, Barneche F

(2018) - eLife

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34. Author Correction: The transcriptional repressor complex FRS7-FRS12 regulates flowering time and growth in Arabidopsis.

Ritter A, Iñigo S, Fernández-Calvo P, Heyndrickx KS, Dhondt S, Shi H, De Milde L, Bossche RV, De Clercq R, Eeckhout D, Ron M, Somers DE, Inzé D, Goossens A

(2018) - Nature communications

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33. Identification of factors required for m6 A mRNA methylation in Arabidopsis reveals a role for the conserved E3 ubiquitin ligase HAKAI.

Růžička K, Zhang M, Campilho A, Bodi Z, Kashif M, Saleh M, Eeckhout D, El-Showk S, Li H, Zhong S, De Jaeger G, Mongan NP, Hejátko J, Helariutta Y, Fray RG

(2017) - The New phytologist

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32. The transcriptional repressor complex FRS7-FRS12 regulates flowering time and growth in Arabidopsis.

Ritter A, Iñigo S, Fernández-Calvo P, Heyndrickx KS, Dhondt S, Shi H, De Milde L, Vanden Bossche R, De Clercq R, Eeckhout D, Ron M, Somers DE, Goossens A

(2017) - Nature communications

DOI
31. Functional characterization of the Arabidopsis transcription factor bZIP29 reveals its role in leaf and root development.

Van Leene J, Blomme J, Kulkarni SR, Cannoot B, De Winne N, Eeckhout D, Persiau G, Van De Slijke E, Vercruysse L, Vanden Bossche R, Heyndrickx KS, De Jaeger G

(2016) - Journal of experimental botany

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30. The SBT6.1 subtilase processes the GOLVEN1 peptide controlling cell elongation.

Ghorbani S, Hoogewijs K, Pečenková T, Fernandez A, Inzé A, Eeckhout D, Kawa D, De Jaeger G, Beeckman T, Madder A, Van Breusegem F, Hilson P

(2016) - Journal of experimental botany

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29. Transferring an optimized TAP-toolbox for the isolation of protein complexes to a portfolio of rice tissues.

Dedecker M, Van Leene J, De Winne N, Eeckhout D, Persiau G, Van De Slijke E, Cannoot B, Vercruysse L, Dumoulin L, Wojsznis N, Gevaert K, De Jaeger G

(2016) - Plant molecular biology

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28. Isolation of protein complexes from the model legume Medicago truncatula by tandem affinity purification in hairy root cultures.

Goossens J, De Geyter N, Walton A, Eeckhout D, Mertens J, Pollier J, Fiallos-Jurado J, De Keyser A, De Clercq R, Van Leene J, Gevaert K, De Jaeger G, Goossens A

(2016) - The Plant journal : for cell and molecular biology

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27. A Repressor Protein Complex Regulates Leaf Growth in Arabidopsis.

Gonzalez N, Pauwels L, Baekelandt A, De Milde L, Van Leene J, Besbrugge N, Heyndrickx KS, Cuéllar Pérez A, Durand AN, De Clercq R, Van De Slijke E, Inzé D

(2015) - The Plant cell

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26. Dynamic Changes in ANGUSTIFOLIA3 Complex Composition Reveal a Growth Regulatory Mechanism in the Maize Leaf.

Nelissen H, Eeckhout D, Demuynck K, Persiau G, Walton A, van Bel M, Vervoort M, Candaele J, De Block J, Aesaert S, Van Lijsebettens M, Goormachtig S, De Jaeger G

(2015) - The Plant cell

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25. An improved toolbox to unravel the plant cellular machinery by tandem affinity purification of Arabidopsis protein complexes.

Van Leene J, Eeckhout D, Cannoot B, De Winne N, Persiau G, Van De Slijke E, Vercruysse L, Dedecker M, Verkest A, Vandepoele K, Martens L, Witters E, De Jaeger G

(2014) - Nature protocols

DOI
24. Sulfenome mining in Arabidopsis thaliana.

Waszczak C, Akter S, Eeckhout D, Persiau G, Wahni K, Bodra N, Van Molle I, De Smet B, Vertommen D, Gevaert K, De Jaeger G, Van Montagu M, Messens J, Van Breusegem F

(2014) - Proceedings of the National Academy of Sciences of the United States of America

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23. The Cyclin-Dependent Kinase Inhibitor KRP6 Induces Mitosis and Impairs Cytokinesis in Giant Cells Induced by Plant-Parasitic Nematodes in Arabidopsis.

Vieira P, De Clercq A, Stals H, Van Leene J, Van De Slijke E, Van Isterdael G, Eeckhout D, Persiau G, Van Damme D, Verkest A, Antonino de Souza JD, Engler JD

(2014) - The Plant cell

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22. The TPLATE adaptor complex drives clathrin-mediated endocytosis in plants.

Gadeyne A, Sánchez-Rodríguez C, Vanneste S, Di Rubbo S, Zauber H, Vanneste K, Van Leene J, De Winne N, Eeckhout D, Persiau G, Van De Slijke E, Van Damme D

(2014) - Cell

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21. A generic tool for transcription factor target gene discovery in Arabidopsis cell suspension cultures based on tandem chromatin affinity purification.

Verkest A, Abeel T, Heyndrickx KS, Van Leene J, Lanz C, Van De Slijke E, De Winne N, Eeckhout D, Persiau G, Van Breusegem F, Inzé D, Vandepoele K, De Jaeger G

(2014) - Plant physiology

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20. ANGUSTIFOLIA3 binds to SWI/SNF chromatin remodeling complexes to regulate transcription during Arabidopsis leaf development.

Vercruyssen L, Verkest A, Gonzalez N, Heyndrickx KS, Eeckhout D, Han SK, Jégu T, Archacki R, Van Leene J, Andriankaja M, De Bodt S, Abeel T, Inzé D

(2014) - The Plant cell

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19. The clathrin adaptor complex AP-2 mediates endocytosis of brassinosteroid insensitive1 in Arabidopsis.

Di Rubbo S, Irani NG, Kim SY, Xu ZY, Gadeyne A, Dejonghe W, Vanhoutte I, Persiau G, Eeckhout D, Simon S, Song K, Kleine-Vehn J, Friml J, De Jaeger G, Russinova E

(2013) - The Plant cell

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18. Generation of VHH antibodies against the Arabidopsis thaliana seed storage proteins.

De Meyer T, Eeckhout D, De Rycke R, De Buck S, Muyldermans S, Depicker A

(2013) - Plant molecular biology

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17. A protein phosphatase 2A complex spatially controls plant cell division.

Spinner L, Gadeyne A, Belcram K, Goussot M, Moison M, Duroc Y, Eeckhout D, De Winne N, Schaefer E, Van De Slijke E, Persiau G, Witters E, Gevaert K, Pastuglia M

(2013) - Nature communications

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16. Selection of scFv phages specific for chloramphenicol acetyl transferase (CAT), as alternatives for antibodies in CAT detection assays.

Van Dorst B, Mehta J, Rouah-Martin E, Backeljau J, De Coen W, Eeckhout D, De Jaeger G, Blust R, Robbens J

(2011) - Journal of applied toxicology : JAT

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15. Isolation of transcription factor complexes from Arabidopsis cell suspension cultures by tandem affinity purification.

Van Leene J, Eeckhout D, Persiau G, Van De Slijke E, Geerinck J, Van Isterdael G, Witters E, De Jaeger G

(2011) - Methods in molecular biology (Clifton, N.J.)

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14. The Arabidopsis bHLH transcription factors MYC3 and MYC4 are targets of JAZ repressors and act additively with MYC2 in the activation of jasmonate responses.

Fernández-Calvo P, Chini A, Fernández-Barbero G, Chico JM, Gimenez-Ibanez S, Geerinck J, Eeckhout D, Schweizer F, Godoy M, Franco-Zorrilla JM, Solano R

(2011) - The Plant cell

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13. Targeted interactomics reveals a complex core cell cycle machinery in Arabidopsis thaliana.

Van Leene J, Hollunder J, Eeckhout D, Persiau G, Van De Slijke E, Stals H, Van Isterdael G, Verkest A, Neirynck S, Buffel Y, De Bodt S, Maere S, De Jaeger G

(2010) - Molecular systems biology

DOI
12. A bioanalytical method for the proteome wide display and analysis of protein complexes from whole plant cell lysates.

Remmerie N, Roef L, Van De Slijke E, Van Leene J, Persiau G, Eeckhout D, Stals H, Laukens K, Lemière F, Esmans E, Van Onckelen H, Inzé D, De Jaeger G, Witters E

(2009) - Proteomics

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11. Mitochondrial type-I prohibitins of Arabidopsis thaliana are required for supporting proficient meristem development.

Van Aken O, Pecenková T, van de Cotte B, De Rycke R, Eeckhout D, Fromm H, De Jaeger G, Witters E, Beemster GT, Inzé D, Van Breusegem F

(2007) - The Plant journal : for cell and molecular biology

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10. A tandem affinity purification-based technology platform to study the cell cycle interactome in Arabidopsis thaliana.

Van Leene J, Stals H, Eeckhout D, Persiau G, Van De Slijke E, Van Isterdael G, De Clercq A, Bonnet E, Laukens K, Remmerie N, Henderickx K, De Jaeger G

(2007) - Molecular & cellular proteomics : MCP

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9. CD3 x CD28 cross-interacting bispecific antibodies improve tumor cell dependent T-cell activation.

Willems A, Schoonooghe S, Eeckhout D, De Jaeger G, Grooten J, Mertens N

(2005) - Cancer immunology, immunotherapy : CII

DOI
8. A technology platform for the fast production of monoclonal recombinant antibodies against plant proteins and peptides.

Eeckhout D, De Clercq A, Van De Slijke E, Van Leene J, Stals H, Casteels P, Persiau G, Vercammen D, Van Breusegem F, Zabeau M, Inzé D, Jespers L, De Jaeger G

(2004) - Journal of immunological methods

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7. Type II metacaspases Atmc4 and Atmc9 of Arabidopsis thaliana cleave substrates after arginine and lysine.

Vercammen D, van de Cotte B, De Jaeger G, Eeckhout D, Casteels P, Vandepoele K, Vandenberghe I, Van Beeumen J, Inzé D, Van Breusegem F

(2004) - The Journal of biological chemistry

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6. Isolation and characterization of recombinant antibody fragments against CDC2a from Arabidopsis thaliana.

Eeckhout D, Fiers E, Sienaert R, Snoeck V, Depicker A, De Jaeger G

(2000) - European journal of biochemistry

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5. The plantibody approach: expression of antibody genes in plants to modulate plant metabolism or to obtain pathogen resistance.

De Jaeger G, De Wilde C, Eeckhout D, Fiers E, Depicker A

(2000) - Plant molecular biology

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4. Analysis of the interaction between single-chain variable fragments and their antigen in a reducing intracellular environment using the two-hybrid system.

De Jaeger G, Fiers E, Eeckhout D, Depicker A

(2000) - FEBS letters

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3. High level accumulation of single-chain variable fragments in the cytosol of transgenic Petunia hybrida.

De Jaeger G, Buys E, Eeckhout D, De Wilde C, Jacobs A, Kapila J, Angenon G, Van Montagu M, Gerats T, Depicker A

(1999) - European journal of biochemistry

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2. Use of phage display for isolation and characterization of single-chain variable fragments against dihydroflavonol 4-reductase from Petunia hybrida.

De Jaeger G, Buys E, Eeckhout D, Bruyns AM, De Neve M, De Wilde C, Gerats T, Van Montagu M, Fischer R, Depicker A

(1997) - FEBS letters

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1. Surface expression and ligand-based selection of cDNAs fused to filamentous phage gene VI.

Jespers LS, Messens JH, De Keyser A, Eeckhout D, Van den Brande I, Gansemans YG, Lauwereys MJ, Vlasuk GP, Stanssens PE

(1995) - Bio/technology (Nature Publishing Company)

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