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Information about the current and former group members
Alain Goossens
Principle investigator at VIB and Professor (5%) at Ghent University
Alain Goossens (born 1971) has studied Biology-Plant Biotechnology at Ghent University and obtained his PhD in Marc Van Montagu’s lab at the Laboratory of Genetics, Ghent University (1998), studying plant seed storage protein synthesis. Subsequently, he performed postdoctoral studies at the IBMCP in Valencia (Spain) in the lab of Ramón Serrano, working on yeast salt tolerance. He returned to VIB-Ghent University and started his own research group within the VIB Department of Plant Systems Biology at Ghent University in 2003, focusing on jasmonate signaling, gene discovery in plant secondary metabolism and metabolic engineering. He is teaching ‘Metabolic Engineering’ at Ghent University.
Tel: +32 (0)9 331 3851 e-mail:
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POSTDOCTORAL RESEARCHERS
Gino Baart
Gino obtained the B.Sc. degree in Chemical Engineering from Eindhoven Polytechnic (1997), the M.Sc. degree in Biotechnology from Wageningen University (1999) and the Ph.D. degree in Life sciences from Wageningen University (2008). From 1999 to 2006 he worked as bioprocess engineer physiology and senior scientist at the Netherlands Vaccine Institute where he also did his Ph.D. research. In 2007 Gino moved to the Department of Applied Mathematics, Biometrics and Process Control of Ghent University where he worked as a project manager metabolic modelling and metabolic engineering. Early 2009 he joined the PSB Department and the Laboratory of Protistology & Aquatic Ecology where he is working as postdoctoral fellow on metabolic modelling and metabolic engineering of diatoms.
Tel: +32 (0)9 331 3850 e-mail:
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Laurens Pauwels

Laurens Pauwels obtained his PhD in the Secondary Metabolites group in June 2009. His research focused on the regulation of gene expression by the jasmonate plant stress hormone in Arabidopsis thaliana and the molecular players involved. As a postdoc he has been working at University of California, Davis, CA, US, to study the regulation of JAZ protein stablity by a new E3 ubiquitin ligase. In September 2010 he has returned to the lab to continue studying the jasmonate signaling complex.
Tel: +32 (0)9 331 3854 e-mail:
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PREDOCTORAL RESEARCHERS
Amparo Cuellar-Perez
Amparo graduated as an Agricultural Engineer at the Universidad Politecnica de Valencia, Spain, in 2008, after doing her Master Thesis in the PSB Functional Genomics Group. In 2009 she started her PhD research, in which she will study jasmonate signalling cascades in Arabidopsis. The knowledge gained will also be translated to the medicinal plant Catharanthus roseus, in particular with the aim to engineer the terpenoid indole alkaloid pathway in that species.
Tel: +32 (0)9 331 3854 e-mail:
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Nathan De Geyter
Nathan De Geyter graduated magna cum laude in Biology at the University of Ghent in 2009, after finishing his Master Thesis on nodulation in the PSB lab of Plant-Microbe Interactions. In 2010, he started his PhD research at the PSB department after he obtained a scholarship from the IWT. His work focuses on the Tandem Affinity Purification (TAP) technology in the model legume Medicago truncatula. Thus, integrating both labs of P-M Interactions and Secondary Metabolites, who work on this remarkable model plant. Using the TAP technique one can identify all unknown protein interactors from a known ‘bait’ protein. The baits that will be further investigated are involved in MeJA-dependent regulation of secondary metabolism.
Tel: +32 (0)9 331 3905 e-mail:
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Michele Fabris
Michele Fabris obtained his BsC Biology in 2005 at the University of Bologna (Italy) and his MsC in Molecular Biology at the same university in 2008. His master thesis focused on jasmonate responses and poylamine accumulation in tobacco plants. After his graduation he still worked on auxin signalling and secondary metabolism at the University of Bologna. In February 2009 he started his PhD at PSB dealing with the modelling and engineering of lipid metabolism of the pennate diatom Phaeodactylum tricornutum.
Tel: +32 (0)9 331 3856 e-mail:
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Azra Gholami
Azra Gholami, a graduate in pharmacy from Shiraz University of Medical Science and Health Services, Iran, started her work as a PhD student at PSB in 2009. Her project focuses on exploring regulatory gene sets that act as jasmonate-modulated master switches towards the biosynthesis of triterpene saponins and flavonoids in the model legume Medicago truncatula. Furthermore she will assess the utility of such genes as tools for metabolic engineering towards increased production of plant-derived pharmaceuticals.
Tel: +32 (0)9 331 3854 e-mail:
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Michiel Matthijs
Michiel Matthijs obtained a master in biotechnology/biochemistry at the university of Ghent in 2009. The subject of his thesis was a comparison of the /Arabidopsis /and human cell cycle. After graduation he started his Phd, funded by the IWT, on the accumulation of lipids in the model diatom Phaeodactylum tricornutum. The main focus of his work is finding genes that increase lipid productivity and subsequently modifying them through genetic techniques. An increased understanding of the lipid metabolism should benefit the diatom research community and in the long term may translate into applications.
Tel: +32 (0)9 331 3856 e-mail:
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Tessa Moses
Tessa Moses, a graduate in Microbiology from the University of Mumbai, India, obtained a predoctoral position in the VIB International PhD program of 2007, to work on the biosynthesis of novel plant derived drugs in engineered plants and yeasts. In her project she will combine cutting-edge functional genomics techniques from the VIB departments PSB at UGent and Molecular and Developmental Genetics at KULeuven, for large-scale analysis of genes involved in plant metabolism. Thereby she plans to create a combinatorial biosynthesis platform, allowing the production of novel biologically active plant derived molecules, in particular triterpene saponins.
Tel: +32 (0)9 331 3855 e-mail:
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Jacob Pollier
In 2003, Jacob Pollier obtained an engineering degree in biochemistry at the Hogeschool Gent. After finishing a masters course in Biotechnology at Ghent University, he started a PhD in 2005. The aim of his research is to obtain proof of concept for combinatorial biochemistry in plants, focusing on the secondary metabolite class of the triterpene saponins. Thereby he employs large-scale gene discovery programs in six different (medicinal) plant species.
Tel: +32 (0)9 331 3856 e-mail:
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Sandra Soetaert
Sandra Soetaert graduated in Biology at Ghent University in 2007. Afterwards she obtained a master in Applied Pharmaceutical Sciences. In 2008 she started her PhD, studying the biosynthesis of the anti-malarial compound artemisinin in Artemisia annua at the lab of Pharmaceutical Biotechnology, Ghent University, in collaboration with the PSB department. She aims to identify novel genes involved in the biosynthesis of artemisinin or in the formation of the glandular trichomes, the producer organs, that eventually will be of use to engineer increased production of artemisinin in plants or other organisms.
Tel: +32 (0)9 264 8053 e-mail:
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TECHNICAL STAFF
Robin Vanden Bossche
Robin Vanden Bossche gratuaded in 2005 as Bachelor in Biomedical Laboratory Technology at Hogeschool Gent, Departement Vesalius. After working in the microbiological lab of the OLV- hospital in Aalst, he moved to the pathology lab of the UZA in Antwerp (Prof. Dr. Eric Van Mark), to increase his skills in this area. Since 2008, he joined the Secondary Metabolites group in PSB, and contributes to the research on jasmonate signaling and secondary metabolism in Arabidopsis, tobacco and Catharanthus roseus.
Tel: +32 (0)9 331 3854 e-mail:
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FORMER SECONDARY METABOLITES MEMBERS
Valerie De Sutter, PhD - Teacher - Gent, Belgium
Miguel Gonzalez Guzman, PhD - Postdoctoral researcher - Instituto de Biologia Molecular y Celular de Plantas, Universidad Politecnica de Valencia - Valencia, Spain
Lies Maes, PhD - Postdoctoral researcher - Centre National de la Recherche Scientifique (CNRS), Université Aix-Marseille-II, CEA Cadarache, St. Paul-les-Durance Cedex, France
Sofie Tilleman, PhD - Expert - Federaal Agentschap voor de Veiligheid van de Voedselketen (FAVV), Brussel, Belgium
Jan Geerinck, PhD - Postdoctoral researcher - VIB/Ghent University - Belgium
Chloë Van Oostende, PhD - Postdoctoral researcher - University of Nebraska-Lincoln - United States
Miriam Onrubia Ibañez - Predoctoral researcher - Universitat Pompeu Fabra - Barcelona, Spain
Freya Lammertyn - Research associate - Bayer Crop Science - Gent, Belgium
Lander Ingelbrecht - Research associate - Genencor - Brugge, Belgium
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