To explore diatoms for biotechnological applications like sustainable production of fuels, pharmaceuticals, health foods, materials relevant to nanotechnology as well as for pollution mitigation and carbon dioxide abatement we are studying the metabolism of the pennate diatom Phaeodactylum tricornutum.

Diatoms are a widespread group of eukaryotic algae that can be found in oceans, freshwater, soils and on damp surfaces. They have played a crucial role in the global ecosystem for millions of years as they perform about 23% of all photosynthesis on earth. In addition, they are one of the most common types of phytoplankton, the base of the food chain for all marine organisms. Hence, diatoms are truly one of the main engines of our planet. To further explore these exiting organisms for biotechnological applications like sustainable production of fuels, pharmaceuticals, health foods, materials relevant to nanotechnology as well as for pollution mitigation and carbon dioxide abatement we are studying the metabolism of the pennate diatom Phaeodactylum tricornutum. Starting from the genome we are reconstructing a mathematical model of metabolism which will be used as a basis for the identification of metabolic engineering targets. By this technique, organisms can be improved to produce metabolites with a better yield and productivity. We aim to create and to validate new biological resources and technologies for diatom cultivation in photo-bioreactors. The primary targets for the proof-of-concept of our technologies will be lipids derived from diatoms.