eurus 2brassinosteroids2The main interest of the group is the signal transduction pathway that plant cells use to respond to the growth promoting hormones, brassinosteroids.
Brassinosteroids are ubiquitously distributed throughout the plant kingdom sterol derivatives. Brassinosteroid deficient mutants display dramatic developmental defects including dwarfism, male sterility, delayed flowering, reduced apical dominance, and a light-grown morphology when grown in dark. Like their animal counterparts, brassinosteroids regulate the expression of numerous genes, impact the activity of complex metabolic pathways, contribute to the regulation of cell division and differentiation, and help control overall development. Brassinosteroids regulate photomorphogenesis, etiolation and cell expansion. Brassinosteroids have a broad spectrum of activities that have a positive effect on the quantity and quality of crops and they increase plant resistance to stress and pathogens.
Read more ...

endocytosis2Growing evidence suggests that plants have adapted endocytosis for signal transduction and use mechanisms similar to those of animals to regulate receptor internalization, because for example endocytic trafficking plays a role in the regulation of brassinosteroid signaling.
Read more ...

chemical geneticsGenetic studies of brassinosteroid signaling and of its interplay with endocytosis are hampered by gene redundancy, the very dynamic nature of endomembrane trafficking and the high degree of lethality of the genes encoding endomembrane components.

Read more ...

Scientists interested in joining our research group for Postdoctoral or PhD projects can contact:This email address is being protected from spambots. You need JavaScript enabled to view it.. Postdocs are expected to apply for independent fellowships.