CLUSTAL W (1.82) multiple sequence alignment


ENST00000297373         ----MTRDEALPDSHSAQDFYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGG
ENSMUST00000026617      ----MTRDDALPDSHSAQTFYENYEPKEILGRGVSSVVRRCIHKPTCQEYAVKIIDITGG
SINFRUP00000158003      -------------------------------RGVSSVVRRCINKRTSQEYAVKIIDITPS
ENSMUST00000033086      MTLDVGPEDELPDWAAAKEFYQKYDPKDIIGRGVSSVVRRCVHRATGDEFAVKIMEVS-A
ENST00000287479         MTLDVGPEDELPDWAAAKEFYQKYDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEVT-A
ci0100140723            --MDGEKKEELPDINTAKEFYSKYEPKEILGRGVSSCVRRCVDKKTRGEFAVKIIDLTDG
CG18069-RC              ----------MAAPAACTRFSDNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTK--
                                  :        :         : :*. * *:**:.: *  *:*.*::: .  

ENST00000297373         GSFSPEEVRELREATLKEVDILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYL
ENSMUST00000026617      GSFSSEEVQELREATLKEVDILQKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYL
SINFRUP00000158003      DKMTQQEIEEIREATLKEIDILKKVCGQDNIIQLKDCYESKSFFFLVFDLMKRGELFDYL
ENSMUST00000033086      ERLSLEQLEEVRDATRREMHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYL
ENST00000287479         ERLSPEQLEEVREATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYL
ci0100140723            SNKIS---EELRQVTHNEINILKEVSGHVHIIELVDVFETSTFIFLIFQLLKRGELFDYL
CG18069-RC              -KLTARDFQKLEREAR-----ICRKLHHPNIVRLHDSIQEENYHYLVFDLVTGGELFEDI
                               ..::.  :     :: .   : :*: * *  : ..: :*:*:*:  ****: :

ENST00000297373         TEKVTLSEKETRKIMRALLEVICTLHKLNIVHRDLKPENILLDDNMN---IKLTDFGFSC
ENSMUST00000026617      TEKVTLTEKETRKIMRALLEVICTLHKLNIVHRDLKPENILLDDNMN---IKLTDFGFSC
SINFRUP00000158003      TENVTLSEKETRKIMRALMEVVQFLHSQGIVHRDLKPENILLDDEMN---IKLTDFGFSV
ENSMUST00000033086      TEKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDNMQ---IRLSDFGFSC
ENST00000287479         TEKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDNMQ---IRLSDFGFSC
ci0100140723            TEVVKFGERQTRSTMRSLLEAVAYLHSQNIVHRDLKPENILLDDDLN---LHLSDFGFST
CG18069-RC              VAREFYSEADASHCIQQILESVNHCHQNGVVHRDLKPENLLLASKAKGAAVKLADFGLAI
                        .      * ::   :: ::* :   *  .:*********:** .. :   ::*:***:: 

ENST00000297373         QLE-PGERLREVCGTPSYLAPEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWH
ENSMUST00000026617      QLQ-PGEKLREVCGTPSYLAPEIIQCSMDDGHPGYGKEVDMWSTGVIMYTLLAGSPPFWH
SINFRUP00000158003      QIN-PGQTLKEVCGTPGYLAPEIIECSMDAGHKGYGTAVDIWSSGVIMYTLLAGSPPFWH
ENSMUST00000033086      HLE-AGEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWH
ENST00000287479         HLE-PGEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWH
ci0100140723            KIE-NGKYFTELYGTPGYMSPEMLKCTVDEHHHGYGVEIDIWACGVIMYTLLAGAPPFWH
CG18069-RC              EVQGDHQAWFGFAGTPGYLSPEVLKK------EPYGKSVDIWACGVILYILLVGYPPFWD
                        .::   :    . ***.*::**:::  :      **  :*:*: ***:: **.* ****.

ENST00000297373         RKQMLMLRMIMSGNYQFGSPEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPFFQQYL
ENSMUST00000026617      RKQMLMLRMIMDGKYQFGSPEWDDYSDTVKDLVSRFLVVQPQDRCSAEEALAHPFFQEYV
SINFRUP00000158003      RKQMLMLRMILAGTYDMSSPEWEDRSDTVKDLISRMLVVDPKQRFTATDVLNHSFFSQYV
ENSMUST00000033086      RRQILMLRMIMEGQYQFTSPEWDDRSNTVKDLISKLLQVDPEARLTAEQALQHPFFERCE
ENST00000287479         RRQILMLRMIMEGQYQFSSPEWDDRSSTVKDLISRLLQVDPEARLTAEQALQHPFFERCE
ci0100140723            RRQMIMLRRIMEGQYSFPSPDWDDISESARDLVSKMLVVDPTKRLTAEMALAHPFFQQVE
CG18069-RC              EDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKRITAAEALKHPWICQRE
                        . *  :   *  * *.  **:*:  :  .::*:.::* *:*  * :*  .* *.:: .  

ENST00000297373         --------VEE---VRHFSPRGKFKVIALTVLASVRIYYQYRRVKPVTREIVIRD-----
ENSMUST00000026617      --------VEE---VRHFSPRGKFKVICLTVLASVKIYYQYRRVKPVTREIVIRD-----
SINFRUP00000158003      --------VHE---VRQFSPYRRFKVICMTVLATMRIYCNYRRAKPVTKEVIKSD-----
ENSMUST00000033086      --------GSQ---PWNLTPRQRFRVAVWTILAAGRVALSSHRLRPLTKNALLRD-----
ENST00000287479         --------GSQ---PWNLTPRQRFRVAVWTVLAAGRVALSTHRVRPLTKNALLRD-----
ci0100140723            --------DTSRYSAKPFNARRKFRVAVHTIVAYHRMAAQVHQHRPLQRAVAARD-----
CG18069-RC              RVASVVHRQETVDCLKKFNARRKLKGAILTTMLATRNFSSRSMITKKGEGSQVKESTDSS
                                         :..  :::    * :   :   .        .     :     

ENST00000297373         ------------------------------------------------------------
ENSMUST00000026617      ------------------------------------------------------------
SINFRUP00000158003      ------------------------------------------------------------
ENSMUST00000033086      ------------------------------------------------------------
ENST00000287479         ------------------------------------------------------------
ci0100140723            ------------------------------------------------------------
CG18069-RC              STTLEDDDIKEDKKGTVDRSTTVVSKEPEAARRQEIIKITEQLIEAINSGDFDGYTKICD
                                                                                    

ENST00000297373         -------PYALRPLRRLIDAYAFRIYGHWVKKGQQQNRAALFENTPKA---------VLL
ENSMUST00000026617      -------PYALRPLRRLIDAYAFRIYGHWVKKGQQQNRAALFENTPKA---------VLL
SINFRUP00000158003      -------PYAVKPIRKLIDACAFKIYGHWVKKGQAQNRAALFENTPKA---------ILL
ENSMUST00000033086      -------PYALRPVRRLIDNCAFRLYGHWVKKGEQQNRAALFQHQPPR---------LFP
ENST00000287479         -------PYALRSVRHLIDNCAFRLYGHWVKKGEQQNRAALFQHRPPG---------PFP
ci0100140723            -------PYSVKCLRRIIDASAFRIYGHWVKKAANQNRATLFENSSRADQRRLQELEEFA
CG18069-RC              PHLTAFEPEALGNLVEGIDFHKFYFENVLGKNCKAINTTILNPHVHLLGEEAACIAYVRL
                               * ::  : . **   * : .   *:    * : *  :                

ENST00000297373         SLAEEDY----------------------------------------------
ENSMUST00000026617      SLAEEEDF---------------------------------------------
SINFRUP00000158003      SIVSE------------------------------------------------
ENSMUST00000033086      IAATELEGDSGAITEDEATLVRS------------------------------
ENST00000287479         IMGPEEEGDSAAITEDEAVLVLG------------------------------
ci0100140723            SAVNEDGLLMCPISSAGNSLIPQSVS---------------------------
CG18069-RC              TQYIDKQGHAHTHQSEETRVWHKRDNKWQNVHFHRSASAKISGATTFDFIPQK
                            :