CLUSTAL W (1.82) multiple sequence alignment


ENST00000278379         ------------------ANNMPKQVEVRMHDSHLGSEEPKHRHLGLRLCDKLGKNLLLT
ENSMUST00000005220      ------------------ANNMPKQVEVRMHDSHLSSDEPKHRNLGMRMCDKLGKNLLLS
ci0100139512            --------------------------------------------MGFTCKQFVKKNALLL
ENSMUST00000025875      --------------------------------------MGKPTSSGCDWRRFLRNHWLLL
ENST00000262352         --------------------------------------MGKPARKGCEWKRFLKNNWVLL
SINFRUP00000139924      ------------------------------------------------------------
ENST00000221742         MSSHGNSLFLRESGQRLGRVGWLQRLQESLQQRALRTRLRLQTMTLEHVLRFLRRNAFIL
ENSMUST00000005490      MSSHGNSLFLRESGAGG---GCLQGLQDSLQQRALRTRLRLQTMTREHVRRFLRRNAFIL
SINFRUP00000151810      -------------------------------------------ISQHSVKGFLQRNLFVL
ENSMUST00000009076      ---------------------------------------MVLDAVLARGRTVCKHNGLLI
CG3747-RB               --------------------------------------MTRPKQDGGKFKAFMQENVLTM
                                                 :   :    :                      .  

ENST00000278379         LTVFGVILGAVCGGLLR-LASPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSG
ENSMUST00000005220      LTVFGVILGAVCGGLLR-LASPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSG
ci0100139512            ATVSGVVLGIVLGIAMR-EAKLSQLDIAYFS-FPGDILLRMLKMMILPLIVCSLITGVAT
ENSMUST00000025875      STVAAVVLGIVLGVVVR-GHSELSNLDKFYFAFPGEILMRMLKLVILPLIVSSMITGVAA
ENST00000262352         STVAAVVLGITTGVLVR-EHSNLSTLEKFYFAFPGEILMRMLKLIILPLIISSMITGVAA
SINFRUP00000139924      --------GICLGTVVR-EYANLSSLDKQYFGFPGEILMRMLKLVILPLIVSSMITGVAA
ENST00000221742         LTVSAVVIGVSLAFALR-PYQ-LTYRQIKYFSFPGELLMRMLQMLVLPLIVSSLVTGMAS
ENSMUST00000005490      LTVSAVIIGVSLAFALR-PYQ-LSYRQIKYFSFPGELLMRMLQMLVLPLIVSSLVTGMAS
SINFRUP00000151810      LTISAVALGVILGFATR-PGK-LSPREIKYLTFPGELLMRMLQMLVLPLIISSLVTGISA
ENSMUST00000009076      LSVLSVIVGCLLGFFLR-TQR-LSPQEISYFQFPGELLMRMLKMLILPLVVSSLMSGLAS
CG3747-RB               ATVIGVFVGGLIGFIIKNSTGEWSKREIMYISFPGEIFLRMLKCLIVPLLVSSITSAIGG
                          :  : :*   .   :               ***::::***: :::**::.*: :.:. 

ENST00000278379         LDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLG--PGKKNDEVSSL
ENSMUST00000005220      LDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLG--PGKKNDEVSSL
ci0100139512            LDQKASGKLGALAVTYYMTTTLIAVIIGIVLVVTINPGR-AGKETID--STGSSISVEAV
ENSMUST00000025875      LDSNVSGKIGLRAVVYYFSTTVIAVILGIVLVVSIKPGVTQKVNDIN--RTGKTPEVSTM
ENST00000262352         LDSNVSGKIGLRAVVYYFCTTLIAVILGIVLVVSIKPGVTQKVGEIA--RTGSTPEVSTV
SINFRUP00000139924      LDSEVSGRIGLYAVIYYFSTTIIAVILGIILVMTIRPGVTQTSEHIN--RTGTPPNVTTV
ENST00000221742         LDNKATGRMGMRAAVYYMVTTIIAVFIGILMVTIIHPGKGSKEGLHR--EGR-IETIPTA
ENSMUST00000005490      LDNKATGRMGMRAAVYYMVTTVIAVFIGILMVTIIHPGKGSKEGLHR--EGR-IETVPTA
SINFRUP00000151810      LDNRASGKMGTRAVIYYMLTTLIAVFIGICIVAIIKPGKGSRDTPAG--DERNIEPVPPA
ENSMUST00000009076      LDAKTSSRLGILTVAYYLWTTFLAVVVGIIMVSIIHPGGAAQKETTE--QSG-KPVMSSA
CG3747-RB               LDLSMSSKIATRAITYYFVTTISAVILGICLVTTLRPGQGAKIVETQTESIDKASKVLTP
                        **   :.::.  :  **: **. *..:*: :*  :.**                  : . 

ENST00000278379         DAFLDLIRNLFPENLVQACFQQIQTVTKKV----------------LVAPPPDEEANATS
ENSMUST00000005220      DAFLDLIRNLFPENLVQACFQQIQTVTKKV----------------LVAPPS-EEANTTK
ci0100139512            DALTDLIRNLFPENLVQACFQQYQTMR----------------------EPITEERNIT-
ENSMUST00000025875      DAMLDLIRNMFPENLVQACFQQYKTKREE--------------------VKPVGDPGGNA
ENST00000262352         DAMLDLIRNMFPENLVQACFQQYKTKREE--------------------VKPPSDPEMNM
SINFRUP00000139924      DTLLDLVRNMFPENLVQACFQQYKSKHSQ--------------------PQALAAQGESS
ENST00000221742         DAFMDLIRNMFPPNLVEACFKQFKTQYSTRVVTRTMVRTENGSEPGASMPPPFSVENGTS
ENSMUST00000005490      DAFMDLVRNMFPPNLVEACFKQFKTQYSTRVVTRTIVRTDNGSELGASMSPTSSVENETS
SINFRUP00000151810      DAFLDLIRNMIPRNLVEACFKQYKTVYKKTVPTR------NGT---IALNLTDSLN-LTE
ENSMUST00000009076      DALLDLVRNMFPANLVEATFKQYRTKTTPVIKSP--------RGAAEEAPRRIVIYGVQE
CG3747-RB               DTLMDLVRNMFTDNIIQSTMFQHRTEIYEN------------------------------
                        *:: **:**::. *:::: : * ::                                   

ENST00000278379         AVVSLLNETVTEVPEETKMVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGDQAKLMVDF
ENSMUST00000005220      AVISMLNETMNEAPEETKIVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGEQAKLMVEF
ci0100139512            SLLPIVNETIEVICLQLSTMLLQVGSYKLGINVLGMISFCITFGIIIGRMGDEGVILVKF
ENSMUST00000025875      TEVSVTTAMTT-MSENKTKEYKIVGLYSDGINVLGLIIFCLVFGLVIGKMGEKGQILVDF
ENST00000262352         TEESFTAVMTTAISKNKTKEYKIVGMYSDGINVLGLIVFCLVFGLVIGKMGEKGQILVDF
SINFRUP00000139924      TRIPPLTTTITAVVENITKDHKITGTYVDGANILGLLVFCIVFGLVIGKMGEKGQILLEF
ENST00000221742         FLENVTRALGTLQEMLSFEETVPVPGSANGINALGLVVFSVAFGLVIGGMKHKGRVLRDF
ENSMUST00000005490      ILENVTRALGTLQEVISFEETVPVPGSANGINALGLVVFSVAFGLVIGGMKHKGRVLRDF
SINFRUP00000151810      SKQNLSRTPHATQETA--EELLPVPSSSAGVNALGLVVFSMCLGLVIGNMRQRGQALQDF
ENSMUST00000009076      DNGSRVQNFALDLTPPPEIVYKSEPGTSDGMNVLGIVIFSATMGIMLGRMGDSGTPLVSF
CG3747-RB               ---------TSISPAQPMENWEFKSAQREGSNVLGLVMFSVILGTTIGRMREKGQLLQDF
                                                     * * **:: *   :*  :* * . .  : .*

ENST00000278379         FNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMVTVIIGLIIHGG
ENSMUST00000005220      FNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMITVIVGLIIHGG
ci0100139512            FSAFNEAVMKIVGIVIWYAPIGIIFLIAGEIMKMEDPAKVLEQLGLYMATVIAGLAIHGI
ENSMUST00000025875      FNALSDATMKIVQIIMCYMPIGILFLIAGKIIEVEDWEIFR-KLGLYMATVLSGLAIHSL
ENST00000262352         FNALSDATMKIVQIIMCYMPLGILFLIAGKIIEVEDWEIFR-KLGLYMATVLTGLAIHSI
SINFRUP00000139924      FDALNEATMRLIQIIMCYMPVGILFLIAAKIVEVEDWEIFK-KMGLYMVTVLSGLAIHAT
ENST00000221742         FDSLNEAIMRLVGIIIWYAPVGILFLIAGKILEMEDMAVLGGQLGMYTLTVIVGLFLHAG
ENSMUST00000005490      FDSLNEAIMRLVGIIIWYAPVGILFLIAGKILEMEDMAVLGGQLGMYTLTVIVGLFLHAG
SINFRUP00000151810      FDCLYEAIMRMVAVIIWYTPVGILFLIAGRILEMKNWAEMGSQLGMYTLSVMVGLIIHSL
ENSMUST00000009076      CQCLNESVMKIVAVAGWYFPFGIVFLIAGKILEMDDPKAVGKKLGFYAVTVVCGLVVHGL
CG3747-RB               FTTLSEAMMTITSWVIWISPLGVAFLIAAKIIEMESIAATIQSLGWYFITVMIGLFLHGF
                           : :  * :        *.*:  **...*: :..      .:* *  :*: ** :*. 

ENST00000278379         IFLPLIYFVVTRKNPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFV
ENSMUST00000005220      IFLPLIYFVVTRKNPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEDNLGIDKRVTRFV
ci0100139512            LVLPLIYFIVVRKNPFAYLSGVLQALLTAVATSSSSATLPVTVNCLEQNNKLDKRVTRFV
ENSMUST00000025875      IVLPLLYFIVVRKNPFRFALGMAQALLTALMISSSSATLPVTFRCAEEKNQVDKRITRFV
ENST00000262352         VILPLIYFIVVRKNPFRFAMGMAQALLTALMISSSSATLPVTFRCAEENNQVDKRITRFV
SINFRUP00000139924      ICLPLLFFLVVRKNPYTFTLGMAQALVTALMISSSSATLPVTFRCAEENNRIDKRITRFV
ENST00000221742         IVLPLIYFLVTHRNPFPFIGGMLQALITAMGTSSSSATLPITFRCLEEGLGVDRRITRFV
ENSMUST00000005490      GVLPLIYFLVTHRNPFPFIGGMLQALITAMGTSSSSATLPITFRCLEEGLGVDRRITRFV
SINFRUP00000151810      VVLPLLFFMVTKKNPYNFIGGLLQALITALGTSSSSSTLPITFRCLEENIGVDKQVTRFV
ENSMUST00000009076      LILPLLYFLITKKNPIVFIRGVLQALLIALATSSSSATLPITFKCLLENNHIDRRIARFV
CG3747-RB               GTIAVIFFLGTRRLPYRYIAKLSQVLATAFGTGSSSATMPLTIKCLD-NMGIDPRVTRFV
                          :.:::*: .:: *  :   : *.   *.  .**:.*:*:*..*      :* :::***

ENST00000278379         LPVGATINMDGTALYEAVAAIFIAQMNGVVLDGGQIVTVSLTATLASVGAASIPSAGLVT
ENSMUST00000005220      LPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQIVTVSLTATLASIGAASIPSAGLVT
ci0100139512            LPIGATINMDGTALYEAVAAIFIAQANGIVLNFGQIVTVSVTATFASIGAAGVPQAGLVT
ENSMUST00000025875      LPVGATINMDGTALYEAVAAVFIAQLNGLDLSIGQIVTISITATAASIGAAGVPQAGLVT
ENST00000262352         LPVGATINMDGTALYEAVAAVFIAQLNDLDLGIGQIITISITATSASIGAAGVPQAGLVT
SINFRUP00000139924      LPVGATINMDGTALYEAVAAIFIAQMNDYSLDMGQIVTISITATVASIGAAGVPNAGLVT
ENST00000221742         LPVGATVNMDGTALYEALAAIFIAQVNNYELNLGQITTISITATAASVGAAGIPQAGLVT
ENSMUST00000005490      LPVGATVNMDGTALYEALAAIFIAQVNNYELNLGQITTISITATAASVGAAGIPQAGLVT
SINFRUP00000151810      LPVGATVNMAGTALYEVVAAIFIAQVNDMELNFGHILTISITATAASIGAAGIPQAGLVT
ENSMUST00000009076      LPVGATINMDGTALYEAVAAIFIAQVNNYELDFGQIITISITATAASIGAAGIPQAGLVT
CG3747-RB               IPVGATINMDGTALYEAVAALFIAQYREMSYSFGTIVAVSITATAASIGAAGIPQAGLVT
                        :*:***:** ******.:**:**** .    . * * ::*:*** **:***.:*.*****

ENST00000278379         MLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHLSKSELDTID-SQH
ENSMUST00000005220      MLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHLSKSELDTID-SQH
ci0100139512            LIIVLTAVGLPTEDITLILAIDWLLDRLRTTVNVLGDSIGAGVVAHLSRKDLHLDS-DPD
ENSMUST00000025875      MVIVLSAVGLPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEKLSKKELEQMD-VSS
ENST00000262352         MVIVLSAVGLPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEKLSKKELEQMD-VSS
SINFRUP00000139924      MVIVLTAVGLPANDVTLIMAVDWLLDRFRTMINVLGDAYGAGIIQKLSKRELKRMD-LTS
ENST00000221742         MVIVLTSVGLPTEDITLIIAVDWFLDRLRTMTNVLGDSIGAAVIEHLSQRELELQE-AEL
ENSMUST00000005490      MVIVLTSVGLPTEDITLIIAVDWFLDRLRTMTNVLGDSIGAAVIEHLSQRELELQE-AEL
SINFRUP00000151810      MVIVLASVGLPVEDIGLIIGVDWLLDRLRTATNVLGDSIGAGIVGHLSRQELQTQE-CDP
ENSMUST00000009076      MVIVLTSVGLPTDDINLIIAVDWALDRFRTMINVLGDALAAGIMAHICRKDFAQDMGTEK
CG3747-RB               MVMVLDTVGLEPKDVSLIIAVDWLLDRFRTTINVMCDALGTILVNHLSKNDLASVDRLNA
                        ::::* :***  .*: *::.:** ***:**  **: *: .: :: ::.: ::        

ENST00000278379         RVHEDIEMTKTQSIYDDMKNHRESNSNQCVYAAHNSVIVDECKVTLAANGKSADCSVEEE
ENSMUST00000005220      RMQEDIEMTKTQSIYDD-KNHRESNSNQCVYAAHNSVVIDECKVTLAANGKSADCSVEEE
ci0100139512            DATTDVTVDKRPPSYTS-----DVFENDAMNESK-----DQFSFTKM-------------
ENSMUST00000025875      EVNIVNPFALEPTTLDNEDSDTKKSYVNGGFAVDKS---DTISFTQTSQF----------
ENST00000262352         EVNIVNPFALESTILDNEDSDTKKSYVNGGFAVDKS---DTISFTQTSQF----------
SINFRUP00000139924      DADATDPFALEATS-DDEECE-KKSYVNGGFTVDKS---DAISFTETSQF----------
ENST00000221742         TLPSLGKPYKS-LMAQEKGASRGRGGNESAM-----------------------------
ENSMUST00000005490      TLPSLGKPYKS-LMAQEKGASRGRGGNESVM-----------------------------
SINFRUP00000151810      ESSVIEEEEKSYHLIHLENDEVSYQSSETTM-----------------------------
ENSMUST00000009076      LLPCETKPVTLQEIVAAQQNGCVKSVAEASELTLGPTCPHHIPVQVEQDEDPAAASLDHC
CG3747-RB               EPHELLELGPNGHEMKE-------------------------------------------
                                                                   .            :   

ENST00000278379         PWKREK-----
ENSMUST00000005220      PWKREK-----
ci0100139512            -----------
ENSMUST00000025875      -----------
ENST00000262352         -----------
SINFRUP00000139924      -----------
ENST00000221742         -----------
ENSMUST00000005490      -----------
SINFRUP00000151810      -----------
ENSMUST00000009076      TIEISELETNV
CG3747-RB               -----------