CLUSTAL W (1.82) multiple sequence alignment


ENSMUST00000025729      ----------------------EAVEPSARELFEACRNGDVERVKRLVTPEKVNSRDTAG
ENST00000265985         MSGRRCAGGGAACASAA----AEAVEPAARELFEACRNGDVERVKRLVTPEKVNSRDTAG
SINFRUP00000138445      ------SGGGNPCS--------GAANGAFRELFEACRNGDVSRVKKLVDAVNVNAKDMAG
ci0100148048            MSGRRNTVSGAAYSLPTRSDRATNSHSTARDLFDACRNGDLNKVKKLVTTQNVNARDLEG
CG4719-RA               -----MANSSRSRAILSVNLDAVMANDPLRELFEACKTGEIAKVKKLITPQTVNARDTAG
                        :                        . . *:**:**:.*:: :**:*: . .**::*  *

ENSMUST00000025729      RKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLQHGAD
ENST00000265985         RKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGAD
SINFRUP00000138445      RKSTPLHFAAGFGRKDVVDHLLRTGANVHARDDGGLIPLHNACSFGHSEVVSLLLCQGAD
ci0100148048            RKSTPLHFAAGFGRKDVVEHLLQCGANVHAQDDGGLIPLHNACSFGHAEVVQLLLTRGAD
CG4719-RA               RKSTPLHFAAGYGRREVVEFLLNSGASIQACDEGGLHPLHNCCSFGHAEVVRLLLKAGAS
                        ***********:**::**:.**. **.::* *:*** ****.*****:*** ***  **.

ENSMUST00000025729      PNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGDY
ENST00000265985         PNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAKAVLTGEY
SINFRUP00000138445      PNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLAEPSAKAVLTVVE
ci0100148048            PNSRDNWNYTPLHEAAIKGKLDVCVVLLQSGGDPHIKNADNKTALDLAEPSAKVVLSGEF
CG4719-RA               PNTTDNWNYTPLHEAASKGKVDVCLALLQHGANHTIRNSEQKTPLELADEATRPVLTGEY
                        **: ************ ***:***:.*** *.:  *:*:: ::.*:**: ::: **:   

ENSMUST00000025729      KKDELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLHHGAD
ENST00000265985         KKDELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGAD
SINFRUP00000138445      RCNMCLCSCRSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGAD
ci0100148048            KKDELLEAARGGNEEQLMDLLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVNLLLKQGAD
CG4719-RA               RKDELLEAARSGAEDRLLALLTPLNVNCHASDGRRSTPLHLAAGYNRIGIVEILLANGAD
                        : :  * :.*.* *:::: ***************:************: **::** :***

ENSMUST00000025729      VHAKDKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRIEVCSLL
ENST00000265985         VHAKDKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLL
SINFRUP00000138445      VHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLL
ci0100148048            VHAKDKGGLVPLHNACSYGHFEVTELLIKHGANVNAMDLWQFTPLHEAASKNRVEVCSLL
CG4719-RA               VHAKDKGGLVPLHNACSYGHFDVTKLLIQAGANVNANDLWAFTPLHEAASKSRVEVCSLL
                        *******.************::**:**:: ** *** *** **********.*:******

ENSMUST00000025729      LSYGADPTLLNCHNKSAIDLAPTAQLKERLSYEFKGHSLLQAAREADVTRIKKHLSLEMV
ENST00000265985         LSYGADPTLLNCHNKSAIDLAPTPQLKERLAYEFKGHSLLQAAREADVTRIKKHLSLEMV
SINFRUP00000138445      LSHGADPTLLNCHSKSSVDMAPTPELKERLTYEFKGHSLLQAAREADVAKAKKSLVLEII
ci0100148048            LAHGGDPTTVNCHSKTAVDVAPNRQLQEKLVYEFKGHSLLDAARQADLTRVKKHLTSDSI
CG4719-RA               LSRGADPTLLNCHSKSAIDAAPTRELRERIAFEYKGHCLLDACRKCDVSRAKKLVCAEIV
                        *: *.*** :***.*:::* **. :*:*:: :*:***.**:*.*:.*::: ** :  : :

ENSMUST00000025729      NFKHPQTHETALHCAAASPYPKRKQICELLLRKGANTNEKTKEFLTPLHVASENAHNDVV
ENST00000265985         NFKHPQTHETALHCAAASPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVV
SINFRUP00000138445      NFKHPHTHETALHCAVASPHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVM
ci0100148048            LFCHPHTHDSPLHCAVGSPYPKRRQVTELLIRKGASLNDKNKEFLAPLHIAADKAHIDVL
CG4719-RA               NFVHPYTGDTPLHLAVVSPDGKRKQLMELLTRKGSLLNEKNKAFLTPLHLAAELLHYDAM
                         * ** * ::.** *. **  **:*: *** ***:  *:*.* *::***:*::  * *.:

ENSMUST00000025729      EVVVKHEAKVNALDSLGQTSLHRAAHCGHLQTCRLLLSYGCDPNIISLQGFTALQMGNEN
ENST00000265985         EVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFTALQMGNEN
SINFRUP00000138445      EVLQKHGAKVNALDTLGQTALHRAALAGHLQTCRLLLGYGADASLVSLQGFTAAQMGNEA
ci0100148048            EVLLKNGAKVNILDCLGQTALHRAAQLGLSQVCIVLLNHGVDPTIMSLQGFTAAQMATET
CG4719-RA               EVLLKQGAKVNALDSLGQTPLHRCARD--EQAVRLLLSYAADTNIVSLEGLTAAQLASDS
                        **: *: **** ** ****.***.*     *.  :**.:. *..::**:*:** *:..: 

ENSMUST00000025729      VQQLLQ---EGASLGHSEADRQLLEAAKAGDVETVKKLCT--VQSVNCRDIEGRQSTPLH
ENST00000265985         VQQLLQ---EGISLGNSEADRQLLEAAKAGDVETVKKLCT--VQSVNCRDIEGRQSTPLH
SINFRUP00000138445      VQQILSGVILSVSLLLLRLNRTCCLRGSS-NPPCLQSLCT--AQNVNCRDLEGRHSTPLH
ci0100148048            IQQLLQ----------------LLDAAKAGDLEVVKKLCS--VHNVNCRDMEGRLSTPIH
CG4719-RA               VLKLLK--------NPPDSETHLLEAAKAGDLDTVRRIVLNNPISVNCRDLDGRHSTPLH
                        : ::*.                    ..: :   :: :      .*****::** ***:*

ENSMUST00000025729      FAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLW
ENST00000265985         FAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLW
SINFRUP00000138445      FAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLW
ci0100148048            FAAGYNRVAVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLVKHGASVNVADLW
CG4719-RA               FAAGFNRVPVVQFLLEHGAEVYAADKGGLVPLHNACSYGHYEVTELLVKHGANVNVSDLW
                        ****:***.**::**.***:*:* *******************:****:*** ***:***

ENSMUST00000025729      KFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDLVKDGDTDIQDLLRGDAALLD
ENST00000265985         KFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDLVKDGDTDIQDLLRGDAALLD
SINFRUP00000138445      KFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKDGDTDIQDLLRGDAALLD
ci0100148048            KFTPLHEAAAKGKYEICKLLLKHGADPHKKNRDGNTPLDLVKEGDLDIQDLLRGDVALLD
CG4719-RA               KFTPLHEAAAKGKYDICKLLLKHGADPMKKNRDGATPADLVKESDHDVAELLRGPSALLD
                        **************:******:***** ****** ** ****:.* *: :****  ****

ENSMUST00000025729      AAKKGCLARVKKLSSPDNVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKG
ENST00000265985         AAKKGCLARVKKLSSPDNVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKG
SINFRUP00000138445      AAKKGCLARVQKLCSPDNINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKG
ci0100148048            AAKKGCLARVQKLCTPSNINCRDQQGRNSTPLHLAAGYNNAEVAEYLIEHGADVNAQDKG
CG4719-RA               AAKKGNLARVQRLVTPESINCRDAQGRNSTPLHLAAGYNNFECAEYLLENGADVNAQDKG
                        ***** ****::* :*..:**** ***:************ * ****:::**********

ENSMUST00000025729      GLIPLHNAASYGHVDVAALLIKYNACVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADP
ENST00000265985         GLIPLHNAASYGHVDVAALLIKYNACVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADP
SINFRUP00000138445      GLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADP
ci0100148048            GLIPLHNASSYGHVEIAALLIKSNASVNATDRWAFTPLHEAAQKGRTQLCTLLLAHGADP
CG4719-RA               GLIPLHNASSYGHLDIAALLIKHKTVVNATDKWGFTPLHEAAQKGRTQLCSLLLAHGADA
                        ********:****:::****** :: *****:*.****************:********.

ENSMUST00000025729      TLKNQEGQTPLDLVSADDVSALLTAAMPPSALPTCYKPQ---VLSGVRGPGATADALSSG
ENST00000265985         TLKNQEGQTPLDLVSADDVSALLTAAMPPSALPSCYKPQ---VLNGVRSPGATADALSSG
SINFRUP00000138445      TMKNQEGQTPLDLATADDIRALLIDAMPPDALPSCLKPQATVVSASVVSTGAAGGVVISP
ci0100148048            TMKNQEGQTPLDLATQEDVRCLLIDAAP-----------------------QTATVSSTS
CG4719-RA               YMKNQEGQTPIELATADDVKCLLQDAMATSLSQQALSASTQSLTSSSPAPDATAAAAPGT
                         :********::*.: :*: .**  * .                        :. .    

ENSMUST00000025729      PSSPSSLSAASSLD--------NLSGSFSELSAVVSSSAAEGATGLQRKEDSG-------
ENST00000265985         PSSPSSLSAASSLD--------NLSGSFSELSSVVSSSGTEGASSLEKKEVPG-------
SINFRUP00000138445      SPSPSCLSAASSID--------NLTTPLGELAVGGAAGSVDVTSVSDRKEGEGTDVR---
ci0100148048            KQATQSSSNSNAVD--------DEDG---------EATAASHSIALDPNASTG-------
CG4719-RA               SSSSSSAILSPTTETVLLPTGASMILSVPVPLPLSSSTRISPAQGAEANGAEGSSSDDLL
                          :...   : : :        .             :   . :   : :   *       

ENSMUST00000025729      ----IDFSITQFIRNLGLEHLMDIFEREQITLDVLVEMGHKELKEIGINAYGHRHKLIKG
ENST00000265985         ----VDFSITQFVRNLGLEHLMDIFEREQITLDVLVEMGHKELKEIGINAYGHRHKLIKG
SINFRUP00000138445      --SLLDMTINQFLKSLGLEHLRDIFQREQISLDVLADMGHEELKEIGINAYGHRHKLIKG
ci0100148048            -----EVAVLQLLDRLSLCQYHEMFDKEKITPDVLADMGHTELKDIGITAFGHRHKIIKA
CG4719-RA               PDADTITNVSGFLSSQQLHHLIELFEREQITLDILAEMGHDDLKQVGVSAYGFRHKILKG
                                :  ::    * :  ::*::*:*: *:*.:*** :**::*:.*:*.***::*.

ENSMUST00000025729      VERLIS----GQQG--LNPYLTLN------NSGSGTILIDLSPDDKEFQSVEEEMQSTVR
ENST00000265985         VERLIS----GQQG--LNPYLTLN------TSGSGTILIDLSPDDKEFQSVEEEMQSTVR
SINFRUP00000138445      IERLLG----GQQG--GNPYLTFH------CSSQGTVLIDLATDDKEFQSVEEELQSTIR
ci0100148048            AERLAL----AAADGAVDPMSDINSIAFSRPTQQGSIIIDLKPEDKEFQSVSEEMQTTIR
CG4719-RA               IAQLRSTTGIGNNVN------------------LCTLLVDLLPDDKEFVAVEEEMQATIR
                          :*      .           :  : :       ::::** .:**** :*.**:*:*:*

ENSMUST00000025729      EHRDGGHAGGVFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVN
ENST00000265985         EHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVN
SINFRUP00000138445      EHRDGGNAGGVFSRYNIIKIQKVVNKKLRERYAHRQKEIADENHNHHNERMLFHGSPFIN
ci0100148048            EHKDGGVAGGVYKSYNIIKVQKVQNKRLRERWNHRRIEVGEENHNHSNDRMLFHGSSFIN
CG4719-RA               EHRDNGQAGGYFTRYNIIRVQKVQNRKLWERYAHRRQEIAEENFLQSNERMLFHGSPFIN
                        **:*.* *** :. ***:::*** *::* **: **: *:.:**. : *:*******.*:*

ENSMUST00000025729      AIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPIHKDRSCYICHRQLL
ENST00000265985         AIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLL
SINFRUP00000138445      AIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPTHKDRSCYVCHRQML
ci0100148048            AIVQKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGINGGTGCPMHKDRSCYICHRQMI
CG4719-RA               AIVQRGFDERHAYIGGMFGAGIYFAEHSSKSNQYVYGIGGGIGCPSHKDKSCYVCPRQLL
                        **:::*********************:***********.** *** ***:***:* **::

ENSMUST00000025729      FCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQI
ENST00000265985         FCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQI
SINFRUP00000138445      FCRVTLGKSFLQFSAMKMAHAPPGHHSVIGRPSVNGLAYAEYVIYRGEQAYPEYLITYQI
ci0100148048            FCRVTLGKSFLQFSAMKMAHAPPGHHSVIGRPSVGGLSHAEYVIYRGEQAYPEYLITYQI
CG4719-RA               LCRVALGKSFLQYSAMKMAHAPPGHHSVVGRPSAGGLHFAEYVVYRGEQSYPEYLITYQI
                        :***:*******:*******:******* ****..**  ****:*****:**********

ENSMUST00000025729      VRPEGMVDG-----
ENST00000265985         MRPEGMVDG-----
SINFRUP00000138445      VKPE----------
ci0100148048            VKPPDETSTSQA--
CG4719-RA               VKPDDSSSGTEDTR
                        ::*