CLUSTAL W (1.82) multiple sequence alignment


ENST00000218089         ------------MIAAPEIPTDFNLLQESETHFSS-----------DTDFEDIEGKNQKQ
SINFRUP00000160405      ------------------------------------------------------------
ci0100130900            ------------------------------------------------------------
CG3423-RA               MDDPPPDYEELHSDALNESTSDADSPTKRMTRLRARGGVRDKPPIIDDDEDDFFAPIARK
                        :         :                     :     :     ::      :       

ENST00000218089         GKGKTCKKGKKGPAEKGKGGNGGGKPPSGPNRMNGHHQQNGVENMMLFEVVKMGKSAMQS
SINFRUP00000160405      ---------------------------------------------------------FQS
ci0100130900            -------------------------------------------NATLYEIVRQGKMAMSS
CG3423-RA               RKTPATRKGPTERKERVERPRKEPVDKGHHERID-SEREITTDENSLYYIVRHSKNPIAS
                                                        :             :  ::      : *

ENST00000218089         VVDDWIESYKHDRDIALLDLINFFIQCSGCKGVVTAEMFRHMQN--SEIIRKMTEEFDED
SINFRUP00000160405      VIDDWIEAYKNDRDIALLDLINFFIQCSGCKGAVSAEMFRQMQN--SEIIRKMTEEFDED
ci0100130900            VVDDWIDAYKTDRNGALLDLIQFFIHASGCKGTVTPKMMQEVSEGFQDVIKQMTEQFDED
CG3423-RA               IVDQWIEQYKANRETALVALMQFFINASGCKGKISEDIQYPVDH--TSIIRRMTEEFDEE
                        ::*:**: ** :*: **: *::***:.***** :: .:   :..   .:*::***:***:

ENST00000218089         SGDYPLTMAGPQWKKFKSSFCEFIGVLVRQCQYSIIYDEYMMDTVISLLTGLSDSQVRAF
SINFRUP00000160405      SGDYPFTLSGPQWKKFRISFCDFIAVLVRHCQYSIIYDEYMMDTVISLLTGLSDSQVRAF
ci0100130900            SGDYPLIATGAHHRKFRSSFCDFVQALVRQCQYEIIYDQFMMDNILTLLTELSNSQVRAF
CG3423-RA               SGEYPLIMSGTQWRKFKNNFCDFVQTLVKQCQYSIIYDQFLMDNVISLLTGLSDSQVRAF
                        **:**:  :*.: :**: .**:*: .**::***.****:::**.:::*** **:******

ENST00000218089         RHTSTLAAMKLMTALVNVALNLSINMDNTQRQYEAERNKMIGKRANERLELLLQKRKELQ
SINFRUP00000160405      RHTSTLAAMKLMTALVNVALNLSINMDNTQRQYEAERNKVMAKRANDRLELLLQKRKELQ
ci0100130900            RHTSTLAAMKLMTGLVNVALQLSVSLDNTQRQYDAEHNKTISKRASEKLDILMQKRKELE
CG3423-RA               RHTATLAAMKLMTALVDVALLVSNNFDNAAKQFEAERVKSRDRRASDRLDSLMTKRSELE
                        ***:*********.**:*** :* .:**: :*::**: *   :**.::*: *: **.**:

ENST00000218089         ENQDEIENMMNAIFKGVFVHRYR-------------FNALSHLFFFFFL-----------
SINFRUP00000160405      ENQDEIENMMNAIFKGVFVHRYRDAIAEIRAVCIEEIGVWMKLYSDAFLNDSYLKYVGWT
ci0100130900            EQQSEIEGMLNGIFKGIFILRYRDFIAEIRALCMDEIGAWMRMFSKVFLTDSYLKYVGWT
CG3423-RA               ENMDEIKSMLTYMFKSVFVHRYRDSLPDIRAICMAEIGIWMENYPQNFLDDSYLKYIGWT
                        *: .**:.*:. :**.:*: ***  :  :  : :  :.   . :   **    :  :   

ENST00000218089         ----QGEVRLKCLTALQGLYYNKELNSKLELFTSRFKDRIVSMTLDKEYDVAVQAIKLLT
SINFRUP00000160405      LHDKQGEVRLKCLTSLQGLFYNRELGARLELFTSRFKDRIVSMTLDKEYDVAVQAIRLLT
ci0100130900            LHDKQKEVRTKCLNTLIGLYGDNDMTRDLKLFTSRFKDRIVSMTLDKEYDVAVLAIKLLY
CG3423-RA               LHDKIGEVRLRCLQSLLPLYEKDELKGKLELFTSKFKDRIVAMTLDKEFEVSVHAVKLVI
                        :     *** :** :*  *: . ::   *:****:******:******::*:* *::*: 

ENST00000218089         LVLQSS---EEVLTAEDCENVYHLVYSAHRPVAVAAGEFLYKKLFSRRDPEEDGMMKRRG
SINFRUP00000160405      LVLQSS---DEVLSAEDCESVYHLVYSAHRPIAVAAGEFLFKKLFSHRGLEEEGLP-RRG
ci0100130900            LILSNCGYDTPVLTSSDCESVYQLVFSCHRPVAVAAAEFLNKQLFMDKDVN-PGYTKRGK
CG3423-RA               SILKIH---PEILADKDCEIVYELVYSSHRGVAQAAAEFLNVRLFHLTADMEETKTKRGK
                         :*.       :*: .*** **.**:*.** :* **.***  :**            *  

ENST00000218089         RQGPNANLVKTLVFFFLESELHEHAAYLVDSMWDCATELLKDWECMNSLLLEEPLSGEEA
SINFRUP00000160405      RQSLNGSLIKTTVFFYLESELHEHGAYLVDSLWECGSELLKDWETMISLLLDEPAPGEEA
ci0100130900            RRGVNAPVITDLVLFYMESELHEHATYLVDSLWDVAGSMLKDWECMSDMLLEEPANDRDS
CG3423-RA               VRMPNTPLVRDLVQFFIESELHEHGAYLVDSFIDSN-DMVRDWECMTDLLLEEPGPNEEV
                         :  *  ::   * *::*******.:*****: :   .:::*** * .:**:**  ..: 

ENST00000218089         LTDRQESALIEIMLCTIRQAAECHPPVGRGTGKRV-LTAKEKKTQLDDRTKITELFAVAL
SINFRUP00000160405      LTDRQETALVELMLCAIRQACECHPPIGRGTGKRV-LTAKEKKTQLDDRTRITEMFAVAL
ci0100130900            LDQKQESALVDIMVCSVKQAAEGVPPTGRQGYSKK-SASRDRKIAIEDRLKLTEHFTVAL
CG3423-RA               LDNKQESTLIEIMVSSVKQSATGEVPVGRASNRKCTLSAKELKAIQDEKAKLTEHFIVTL
                        * ::**::*:::*:.:::*:.    * **    :   :::: *   ::: ::** * *:*

ENST00000218089         PQLLAKYSVDAEKVTNLLQLPQYFDLEIYTTGRLEKHLDALLRQIRNIVEKHTDTDVLEA
SINFRUP00000160405      PLLLAKYCVDIDKVTNLLQIPKYFDLDIYTTGRLEKHLDSLLRQIWEVQDKHTDTEVLEA
ci0100130900            PSLLKKFHVDREKVVGLLQIPRYFELECYTTSRREKHLDELLTQLSVVMDKHTEHDVLEE
CG3423-RA               PSLLEKYQADSEKLANLLAVPQYFDLNLYTTNRQEGNLQALLDRINQVMSMHTGREVLET
                        * ** *: .* :*:..** :*:**:*: ***.* * :*: ** ::  : . **  :*** 

ENST00000218089         CSKTYHALCNEEFTIFNRVDISRSQLIDELADKFNRLLEDFL---QEGEEPDEDDAYQVL
SINFRUP00000160405      CSTTYHYLCNEEFTIFNRVDIARSQFLDELVDKFNKLLEDFL---QEGEEPDEDDVYQVL
ci0100130900            VSRTFSHLCDDEFAIFSKVSIARRAVIDKWAENLRFSLAVFK---EAGDNVDDEEVYNVV
CG3423-RA               CAKTLECLCAEGSATYTRCNIARSNIIESAVNKYKDAIEEWRNLIQGEETPNEDDIYNIT
                         : *   ** :  : :.: .*:*  .::. .:: .  :  :  :::  :  :::: *:: 

ENST00000218089         STLKRITAFHKNAEL-----------------------------------------FIQY
SINFRUP00000160405      STLKKISAFHNAHDLSTWDLFTSNYRLLNTGLQ----NGDMPEQIVIHAMQCTHYIILWH
ci0100130900            QNLKRLTHLFMFNDITQWDFVIFTNNFHS-------------LQMLLEAVKFIYYHLVYS
CG3423-RA               ITLKVLSILYSSHNLNPWELFKSLFQDVEEAQSKENIDRCLPNEALVYCIEACYFSISWG
                         .** :: :.   ::    :.               :   :    ::  :      :   

ENST00000218089         FLKVN---------VNFFKEDLLRLKKQMRVFCQICQHYLTN-VNTTVKEQAFTILCDIL
SINFRUP00000160405      LAKVSD--------SNSLKGDMVTLRKQMRAFCLMCQHYLTN-MNTAVKEQAFTILCDLL
ci0100130900            LAGLKKSSTSSGVGSEDPRAAIGLLRKRTAEYLSSCEMLLAKSPYKKIQEESYMSICDLL
CG3423-RA               LQYVEN-----ECESVNVTEVVAELRNNLDTFMGACFELTRDGPTVQIQEAAYQSICDLL
                        :  :.                :  *::.   :   *     .     ::* ::  :**:*

ENST00000218089         MIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDDNNSADGQQEDEASKI
SINFRUP00000160405      LIFSHQMMSSGREHLEPLVFTPDVSLQAELLSFILDQVFVDQDDDSNSTDGQQDDEASKI
ci0100130900            VMFAPQLASSS-PNLKSLVQRASEPLQHSLVDFVREFVFTMPDEDEN------EDDTAKI
CG3423-RA               IIFSDKLARSEIEHIRGLEYKSRMDEHLILDNFVQHYVFSLKQDVAQ--------DETRI
                        ::*: ::  .    :. *   .    :  * .*: . **   ::  :        : ::*

ENST00000218089         EALHKRRNLLAAFCKLIVYTVVEMNTAADIFKQYMK--YYNDYGDIIKETMSKTRQIDKI
SINFRUP00000160405      EALHKRRNLLAAYCKLIIYNVVEMNTGADIFKQYMR--FYNDYGDIIKETMSKTRQIDKV
ci0100130900            DALHQRRSLLAAICKLFVYNMVDLRLAAVVFQQYIRYVFYSDYGDIIKETISKTRHVNKL
CG3423-RA               EELHKKRNFLACYCKLVVYNIIPTMRAASIFKYYVK--CYNDYGDIIKATLGKAREINKV
                        : **::*.:**. ***.:*.::    .* :*: *::   *.******* *:.*:*.::*:

ENST00000218089         QCAKTLILSLQQLFNEMIQE-NGYNFDRSSSTFSGIKELARRFALTFGLDQLKTREAIAM
SINFRUP00000160405      QYSKTLILSLQMLFNDMLSE-LGINIDRSSSAFCGIKELARRFSLTFGLDQMKTREAIAM
ci0100130900            GCAQTLALSLKSLFRETVRE-QGGVLDQSSQEYGHMKELARRFALTFGLDQVKTRDAVAE
CG3423-RA               NFAMTLLLSLITVFKSLQEQSEDGIVSKSSQEFVDLKELAKRFALTFGFDAIKNRESVAA
                          : ** ***  :*..   :  .  ..:**. :  :****:**:****:* :*.*:::* 

ENST00000218089         LHKDGIEFAFK-EPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYVYLEKFMTFQMS
SINFRUP00000160405      LHKDGIEFSFK-EPSPQGEGGPPLNLAFLDILSEFSSKLMRQDKKTVHMYLERFMTFQMA
ci0100130900            LHKEGILFALKRDDAAYNESVAPPNLSFLGILVEFSAKLMRQDKRTVVHYLDKHISPHLL
CG3423-RA               IHRGGIYFAAN--KEPDDPVRAPTRLLFLEVLNEFNYKLLKQDKKVIMSFLDKIIPPAMP
                        :*: ** *: :    . .   .* .* ** :* **. **::***:.:  :*:: :.  : 

ENST00000218089         LRREDVWLPLMSYRNSLLAG-GDDDTMSVISGISSRGSTVRSKKSKPSTGKRKVVEGMQL
SINFRUP00000160405      LQRDDCWLPLISYRNSLQVG-GDDDTMSVVSGISSRGS-SRSKKSKTATANKRKLPEVEE
ci0100130900            SNQDSSWIPLVTYRNSLLQGAGLDDDMAPQNSIGQPQLTSTVMRGKQ-------------
CG3423-RA               SSRAEEWQPLILYRNSLLHG----------------------------------------
                          : . * **: *****  *                                        

ENST00000218089         SLTEESSSSDSMWLSREQTLHTPVMMQTPQLTSTIMREPKRLRPEDSFMSVYPM------
SINFRUP00000160405      ---NSCSSSDSPWLNRDQNLQTPVMMQSPHPNANAVRDSKKMRPEDGYMMAYTMPAVQHP
ci0100130900            ---QMRMTDDQMEYRPSQTMINTSMPMTPQHSMPPPQ-------EYHHQMGYPMS-----
CG3423-RA               ------------------------------------------------------------
                                                                                    

ENST00000218089         ----------QTEHHQTPLDYNRRGTSLMEDDEEPIVEDVMMSSEGRIEDLNEGMDFDTM
SINFRUP00000160405      HQAVPLQQQQHHQHHQAAVDYNRRGSGLLEDDEEPIVEDVMMSSEDRLEDINEGMDFDTM
ci0100130900            ------------VPQQSPIQQIGTPQYMQPSTSSGIYQ---QGGSESYQGVVSPMTQPGM
CG3423-RA               ------------ETDQAPVASKRAYTRKRRDHDE-----------------EEEEEEDEE
                                      .*:.:           . ..                  .       

ENST00000218089         DIDLPPSKNRRERTELKPDFFDPASIMDESV
SINFRUP00000160405      DIDLPASKNRRERTELKPDYFDPSSIMDDS-
ci0100130900            QTQSPYYGN----------------------
CG3423-RA               EHNDPDYRG----------------------
                        : : *   .