CLUSTAL W (1.82) multiple sequence alignment


SINFRUP00000139269      MSTPDPPIGGTPRPGPSPGPGPSPGAMMGPSPGPSPGSSHSMMGPSPGPPSTGHPQPGPS
SINFRUP00000127987      ------------------------------------------------------------
ENST00000265773         ------------------------------------------------------------
CG5942-RC               MASPSPAN-----SPMPPPQAPSPMAPPSQSPAPSPHSPYPHQQPGPLQGPPPPGHPGAY
                        :                                                           

SINFRUP00000139269      GYGQENMHPLHKP---IESMHEKSMSEESRFSQLKGLTVRQAGHSGMGPPPSPLDQHSQG
SINFRUP00000127987      ------------------------------------------------------------
ENST00000265773         ---------MFQP---IDGIHDKGIVEDIHCGSMKGTGMRPP-HPGMGPPQSPMDQHSQG
CG5942-RC               GHPMQHGPPGQGPPGHHMPPHHQGMSPHMGMQMPPTGPNMSPYQTHGMPPNAPTQPCIVS
                                                :                                   

SINFRUP00000139269      KYGPS-----GDQHTLGPNSRPGPPVSAGPGPSPGPNLGPSLGSGLDPAGGTGPTPFNQN
SINFRUP00000127987      ---------------------SGPAASGGPGGVGG--------------GTGGPTPFNQN
ENST00000265773         YMSPHPSPLGAPEHVSSPMSGGGPTPPQMPPSQPGALIPGD--PQAMSQPNRGPSPFSPV
CG5942-RC               PGGPPGGP--PPPERSSQENLHALQRAIDSMEEKGLQEDPRYSQLLAMRATSKHQHLNGN
                                              .   .  .    *                     :.  

SINFRUP00000139269      QLHQLRAQIMAYKMLTRGQPLPDHLQMAVQ----------------------------GK
SINFRUP00000127987      QLHQLRAQIMAYKMLARSQALPEHLQMAVQ----------------------------GK
ENST00000265773         QLHQLRAQILAYKMLARGQPLPETLQLAVQ----------------------------GK
CG5942-RC               QVNLLRTQITAYRLLARNKPISMQMQQALQAAQQQPPPGPPIGPPGAPGGPPPGSQHAGQ
                        *:: **:** **::*:*.:.:.  :* *:*                            *:

SINFRUP00000139269      RPMPGMQQQPIPSLGPGAGGGPVGGVLGPGLGPIGSG--------YSRAHGMMGPNMPPP
SINFRUP00000127987      RPMPGMQQQQMPNMPPITG---PGGGPGAGAGPAQGN--------YNRPHGMVGASVVPP
ENST00000265773         RTLPGLQQQQQQQQ-----------------QQQQQQ--------QQQQQQQQQPQQQPP
CG5942-RC               PPVPPQQQQQPPPSAGTPPQCSTPPASNPYGPPVPGQKMQVAPPPPHMQQGQPLPPQPPQ
                         .:*  ***                                        :    .   * 

SINFRUP00000139269      GPSGAPVGIQGQNQNGPPKSWPEGPMVNAAAPSNTPQKLIPPQPTGRPSPAPPSVPPAAS
SINFRUP00000127987      GAAGVPSAMPGQAINGPPKSWSDGPVVNAATPSNPPQKLIPTQPTGRPSPAPPSVPPAAS
ENST00000265773         ----QPQTQQQQQPALVNYNRPSGPGPELSGPS-TPQKLPVPAPGGRPSPAPPAAAQPPA
CG5942-RC               VGGPPPIQQQQPPQQQQQQSQPPPPEPHQHQLPNGGKPLSMGPSGGQPLIPSSPMQPQVR
                             *             . .  *  .    .   : *    . *:*  ....      

SINFRUP00000139269      PVMP--PQTQSPGQPV-----QPTPMMPYHTKQNRITPIQKPCGLDPVEILQEREYRLQA
SINFRUP00000127987      PVMP--PQTHSPGQPA-----LPPPMM-LHPKQNRITPIQKPRGLDPVEILQEREYRLQA
ENST00000265773         AAVP--GPSVPQPAPG-----QPSPVLQLQQKQSRISPIQKPQGLDPVEILQEREYRLQA
CG5942-RC               GTLPGMPPGSQVPQPGGGPQRQVPPAGMPMPKPNRITTVAKPVGLDPITLLQERENRIAA
                         .:*          *        .*      * .**:.: ** ****: :***** *: *

SINFRUP00000139269      RITHRIAELENLPGSLAGDLRTKATIELKALRLLNFQRQLRQEVVVCMRRDTALETALDA
SINFRUP00000127987      RIAHRIQELENLPGSLPGDLRTKATIELKALRLLNFQRQLRQEVVVCMRRDTALETALNA
ENST00000265773         RIAHRIQELENLPGSLPPDLRTKATVELKALRLLNFQRQLRQEVVACMRRDTTLETALNS
CG5942-RC               RISLRMQELQRLPATMSEDLRLQAAIELRALRVLNFQRQLRMEFVQCTRRDTTLETALNI
                        **: *: **:.**.::. *** :*::**:***:******** *.* * ****:*****: 

SINFRUP00000139269      KAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFKEYHRSITGK
SINFRUP00000127987      KAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFKEYHRSITAK
ENST00000265773         KAYKRSKRQTLREARMTEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFKEYHRSVAGK
CG5942-RC               KLYKRTKRQGLREARATEKLEKQQKLEAERKRRQKHLEFLAAVLQHGKDLREFHRNNKAQ
                        * ***:*** ***** *********:* ******** *:* ::***.**::*:**.  .:

SINFRUP00000139269      MQKLTKAVATYHANTEREQKKENERIEKERMRRLMAEDEEGYRKLIDQKKDKRLAYLLQQ
SINFRUP00000127987      IQKATKAVATYHANTEREQKKENERIEKERMRRLMAEDEEGYRKLIDQKKDKRLAYLLQQ
ENST00000265773         IQKLSKAVATWHANTEREQKKETERIEKERMRRLMAEDEEGYRKLIDQKKDRRLAYLLQQ
CG5942-RC               LARMNKAVMNHHANAEREQKKEQERIEKERMRRLMAEDEEGYRKLIDQKKDKRLAFLLSQ
                        : : .*** . ***:******* ****************************:***:**.*

SINFRUP00000139269      TDEYVANLTELVRAHKAAQAGITPKLTDVRLSLQLEVAEGQAPAMGPDGEPLDETSQMSD
SINFRUP00000127987      TDEYVANLTELVRAHKAAQALKEKKKKKKKK--VIICSSGATALLGPDGEPLDETSQMSD
ENST00000265773         TDEYVANLTNLVWEHKQAQAAKEKKKRRRRKKKAEENAEGGESALGPDGEPIDESSQMSD
CG5942-RC               TDEYISNLTQMVKQHKDDQMKKKEEEGKRLIQFKKELLMSG-EYIG-----IDEGSIVAD
                        ****::***::*  **  *     :              .    :*     :** * ::*

SINFRUP00000139269      LPVKVIHVDSGNILTGVDAPKAGQLDTWLEMNPGYEVAPRSDSEDS---EEEEEEEEEEE
SINFRUP00000127987      LPVKVIHVDSGKILTGIEAPKAGQLEAWLEMNPGYEVAPRSDSEDSGSEEEEEEEDEEED
ENST00000265773         LPVKVTHTETGKVLFGPEAPKASQLDAWLEMNPGYEVAPRSDSEES---DSDYEEEDEEE
CG5942-RC               MRVHVVEQCTGKKLTGDDAPMLKHLHRWLNMHPGWDWID--DEEDSCGSNDDHKPKVEEQ
                        : *:* .  :*: * * :**   :*. **:*:**::     *.*:*   :.: : . **:

SINFRUP00000139269      EPQPSSASMEDKKKITDPDSEDVSEVDVRHIIENAKQDVDDEYSGAAFARGLQSYYAVAH
SINFRUP00000127987      QPQPSSAMTEEKKKIPDPDSEDVSEVDVQHIIEHAKQDVDDEYSNASFNKCLNSYYAVAH
ENST00000265773         E---SSRQETEEKILLDPNSEEVSEKDAKQIIETAKQDVDDEYSMQYSARGSQSYYTVAH
CG5942-RC               P--------TATEDATDKAQATGNDEDAKDLITKAKVE-DDEYR-----TEEQTYYSIAH
                                    :   *  .   .: *.:.:*  ** ::****         ::**::**

SINFRUP00000139269      AVTEKVEKQSTLLVNGQLKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYL
SINFRUP00000127987      AVTEKVEKQSTLLVNGQLKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYL
ENST00000265773         AISERVEKQSALLINGTLKHYQLQGLEWMVSLYNNNLNGILADEMGLGKTIQTIALITYL
CG5942-RC               TIHEKVVEQASIMVNGTLKEYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTISLVTYL
                        :: *:* :*:::::** **.**::****:*************************:*:***

SINFRUP00000139269      MEHKRLNGPYLIIVPLSTLSNWVYEFDKWAPTVVKVSYKGSPAARRAFVPQLRSGKFNVL
SINFRUP00000127987      MEYKRLNGPFLIIVPLSTLSNWVYEFDKWAPSVVKVSYKGSPAARRAFVPILRSGKFNVL
ENST00000265773         MEHKRLNGPYLIIVPLSTLSNWTYEFDKWAPSVVKISYKGTPAMRRSLVPQLRSGKFNVL
CG5942-RC               MDRKKVMGPYLIIVPLSTLPNWVLEFEKWAPAVGVVSYKGSPQGRRLLQNQMRATKFNVL
                        *: *:: **:*********.**. **:****:*  :****:*  ** :   :*: *****

SINFRUP00000139269      LTTYEYIIKDKQVLAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYLAPRRVLLTGTPLQN
SINFRUP00000127987      LTTYEYIIKDKQVLAKLRWKYMIVDEGHRMKNHHCKLTQVLNTHYLAPRRVLLTGTPLQN
ENST00000265773         LTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRILLTGTPLQN
CG5942-RC               LTTYEYVIKDKAVLAKIQWKYMIIDEGHRMKNHHCKLTQVLNTHYIAPYRLLLTGTPLQN
                        ******:**** :***::*****:*********************:** *:*********

SINFRUP00000139269      KLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEETILIIRRLHKVLRPFL
SINFRUP00000127987      KLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEETILIIRRLHKVLRPFL
ENST00000265773         KLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGERVDLNEEETILIIRRLHKVLRPFL
CG5942-RC               KLPELWALLNFLLPSIFKSCSTFEQWFNAPFATTGEKVELNEEETILIIRRLHKVLRPFL
                        **************:***************** ***:*:*********************

SINFRUP00000139269      LRRLKKEVEAQLPEKVEYVINCDMSALQRVLYRHMQAKGVLLD-GSEKDKKGKGGTKTLM
SINFRUP00000127987      LRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTDGSEKDKKGKGGTKTLM
ENST00000265773         LRRLKKEVESQLPEKVEYVIKCDMSALQKILYRHMQAKGILLTDGSEKDKKGKGGAKTLM
CG5942-RC               LRRLKKEVEHQLPDKVEYIIKCDMSALQRVLYKHMQSKGVLLTDGSEKGKHGKGGAKALM
                        ********* ***:****:*:*******::**:***:**:**  ****.*:****:*:**

SINFRUP00000139269      NTIMQLRKICNHPYMFQQIEESFSEHLGFSGGIVQGPDLYRASGKFEVLDRILPKLRATN
SINFRUP00000127987      NTIMQLRKICNHPYMFQHIEVTN--------KLTHYPDLYRSSGKFELLDRILPKLRATN
ENST00000265773         NTIMQLRKICNHPYMFQHIEESFAEHLGYSNGVINGAELYRASGKFELLDRILPKLRATN
CG5942-RC               NTIVQLRKLCNHPFMFQHIEEKYCDHTG-GHGVVSGPDLYRVSGKFELLDRILPKLKATN
                        ***:****:****:***:** .          :   .:*** *****:********:***

SINFRUP00000139269      HKVLLFCQMTSLMTIMEDYFAYRSFKYLRLDGTTKAEDRGMLLKTFNDPESEYFIFLLST
SINFRUP00000127987      HKVLLFCQMTTLMTIMEDYFAYRNFKYLRLDGTTKAEDRGMLLKTFNDPASDYFVFLLST
ENST00000265773         HRVLLFCQMTSLMTIMEDYFAFRNFLYLRLDGTTKSEDRAALLKKFNEPGSQYFIFLLST
CG5942-RC               HRVLLFCQMTQCMTIIEDYLGWRQFGYLRLDGTTKAEDRGELLRKFNAKGSDVFVFLLST
                        *:********  ***:***:.:*.* *********:***. **:.**   *: *:*****

SINFRUP00000139269      RAGGLGLNLQSADTVVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVSSVEEKILA
SINFRUP00000127987      RAGGLGLNLQSADTVVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILA
ENST00000265773         RAGGLGLNLQAADTVVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILA
CG5942-RC               RAGGLGLNLQTADTVVIFDSDWNPHQDLQAQDRAHRIGQRNEVRVLRLMTVNSVEERILA
                        **********:****************************:******** **.****:***

SINFRUP00000139269      AAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDEVWAPATHN--QKMCFLMR
SINFRUP00000127987      AAKYKLNVDQKVIQAGMFDQKSSGYERRAFLQAILEHEEQDEVGKLFVVLGTKDMFHIYK
ENST00000265773         AAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEEN-------------------
CG5942-RC               AARYKLNMDEKVIQAGMFDQKSTGSERQQFLQTILHQDDNEE------------------
                        **:****:*:************:. **: ***:**.::::: :           :  :  

SINFRUP00000139269      CLP--------MCVCCIQEEDEVPDDETVNQMIARSEEEFDQFMRMDLDRRREEARNPRR
SINFRUP00000127987      NISNFIVNGCLLSGIIQQEEDEVPDDETVNQMIARSEEEFEQFMRMDLDRRREEARNPKR
ENST00000265773         -----------------EEEDEVPDDETLNQMIARREEEFDLFMRMDMDRRREDARNPKR
CG5942-RC               -----------------EEENEVPDDEMINMMIARSEEEIEIFKRMDAERKKEDEEIHPG
                         :         :     :**:****** :* **** ***:: * *** :*::*: .    

SINFRUP00000139269      KPRLMEEDELPTWIMKDDAEVERLTCEEEEEKMFGRGSRQRKEVDYSDSLTEKQWLKAIE
SINFRUP00000127987      KPRLMEEDDLPSWILKDDAEVERLTCEEEEEKMFGRGSRQRKEVDYSDSLTEKQWLKAIE
ENST00000265773         KPRLMEEDELPSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDALTEKQWLRAIE
CG5942-RC               RERLIDESELPDWLTKDDDEVERFHYQYDEDTILGRGSRQRKEVDYTDSLTEKEWLKAID
                        : **::*.:** *: *** ****:  : :*:.::*******::***:*:****:**:**:

SINFRUP00000139269      EGTLEEVEEEVRHKKTTRKRRRDRDLDLPGPSSSLGGRGRGDRDDDGKRQRKRGRPPVEK
SINFRUP00000127987      EGNLEDIEEEVRHKKTSRKRKRDRDHDGGPATPSSSSSRVREKDEEGKKTKKRGRPPAEK
ENST00000265773         DGNLEEMEEEVRLKKRKRRRNVDKDP---------------AKEDVEKAKKRRGRPPAEK
CG5942-RC               DGAEFDEEEEEDDSKRKRRKRKNRKE---------------ESDDDSLILKRRRRQNLDK
                        :*   : ***   .* .*::. ::.                  ::     ::* *   :*

SINFRUP00000139269      LSPNPPSLTKKMKKIVDAVIKYKDS-----------------ASGRQLSEVFIQLPSRKE
SINFRUP00000127987      LSPNPLSLTKKMKKIIDAVIKYKD------------------GNGRQLSEVFIQLPSRKE
ENST00000265773         LSPNPPKLTKQMNAIIDTVINYKDRCNVEKVPSNSQLEIEGNSSGRQLSEVFIQLPSRKE
CG5942-RC               RS------KKQMHKIMSAVIKHNQ-------------------DGRTLSEPFMKLPSRQR
                         *     :.*:*: *:.:**::::                   .** *** *::****:.

SINFRUP00000139269      LPEYYELIRKPVDFRKIKERIRGHRYRSLGDLERDVMLLFQNAQTFNLEGSLIYEDSIVL
SINFRUP00000127987      LPEYYELIRKPVDFRKIKERIRSHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVL
ENST00000265773         LPEYYELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCHNAQTFNLEGSQIYEDSIVL
CG5942-RC               LPDYYEIIKRPVDIKKILQRIEDCKYADLNELEKDFMQLCQNAQIYNEEASLIYLDSIAL
                        **:***:*::***::** :**.. :* .*.:**:*.* * :*** :* *.* ** ***.*

SINFRUP00000139269      QSVFTSLRQKID---------------------------SDDISIVMLRSSFDSAP---A
SINFRUP00000127987      QSVFTSVRQKIEENE------------------------SEGDESEEEEEDVDEGSESES
ENST00000265773         QSVFKSARQKIAKEEE-----------------------SEDESNEEEEEEDEEESESEA
CG5942-RC               QKVFVGARQRITAAADAAAVAAGDNTGEAHGNGGSDNSDNDDDDGGDDGSDDEEIATTSA
                        *.** . **:*                            .:. .     .. :. .   :

SINFRUP00000139269      RSVKVKIRLGRKD-KGSDRGKARSRRTGRSRAKPVVSDDDSEDEQEE------------
SINFRUP00000127987      RSVKVKIKLSRKE-KGERGSKVHRRRGRGARAKPVVSDDDTEEDQEEVR----------
ENST00000265773         KSVKVKIKLNKKDDKGRDKGKGK-KRPNRGKAKPVVSDFDSDEEQDEREQSEGSGTDDE
CG5942-RC               AAVKMKLKLNKSLASAPATPTQSSSNVSSGAATTSKKQTRRKRSQKKYTISDDDDDDMD
                         :**:*::*.:.  ..    .    .   . *..  .:   . .*.: