CLUSTAL W (1.82) multiple sequence alignment


ENST00000263078         -----------------------------------------MESALTARDRVGVQDFVLL
ENSMUST00000057572      PGRRDRTGVADSGGGHAVQSSPRPITRRTKPALGSDGVRVTMESALTARDRVGVQDFVLL
SINFRUP00000160392      -----------------------------------------MESALTARDRVGVQDFLLL
SINFRUP00000145776      -----------------------------------------MESSLNARDRVGIQDFVLL
ci0100140769            -----------------------------------------MEGALTARDRVGVQDLVLL
CG9155-RC               -----------------------------------------METGLHERDRAGVQDFVLL
                                                                 ** .*  ***.*:**::**

ENST00000263078         ENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRGVSFYEVPP
ENSMUST00000057572      ENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRGVSFYEVPP
SINFRUP00000160392      ENHNSEAAFIENLRRRLRENLIYTYIGSVLVSVNPYKELEIYSKQQMERYRGISFYEISP
SINFRUP00000145776      DAHTSESAFLDNLRKRFHENLIYTYIGTLLVSVNPYKELDIYSKKQMDTYMGVNFFELPP
ci0100140769            EDYQSETAFLHNIKKRFKEKLIYTYIGSVLISVNPYQQLGFYSPYHMEKYQGVNFYEMPP
CG9155-RC               ENYQSEEAFIGNLKKRFQEDLIYTYIGQVLISVNPYKQLPIYTDDHVKAYRNKHFYEMPP
                        : . ** **: *:::*::*.******* :*:*****::* :*:  ::. * .  *:*:.*

ENST00000263078         HLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPERGGAVRDRL
ENSMUST00000057572      HLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPERGGAVRDRL
SINFRUP00000160392      HIYALSDNTYRAMRTERKDQCILISGESGAGKTEASKKILLYYSVTCPTNDRMASLGECL
SINFRUP00000145776      HIYALADNVFRTMQSEYNNHFILISGESGAGKTEASKKILQFYAVSCPSTRLLNNIRDRL
ci0100140769            HVYAIGDNTYRSMRNEASDQCILISGESGSGKTEASKYILQYLSVCSASNDNVEHIKGRL
CG9155-RC               HIFAVTDNAFRSLIEENRGQCVLISGESGSGKTEASKKVLQFIAACSGNQTTVEGVKDKL
                        *::*: *..:*::  *  .: ::******:*****:* :* : :  .        :   *

ENST00000263078         LQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSRVVHQNHGE
ENSMUST00000057572      LQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSRVVHQNHGE
SINFRUP00000160392      LQSIPVLEAFGNAKTLRNDNSSRFGKYMDIQFDFRGAPVGGHILNYLLEKSRVVHQNHGE
SINFRUP00000145776      LLSNPVLEAFGNAKTLKNDNSSRFGKYMDIQFDHQGGAVGGHILSYLLEKSRVVHQNHGE
ci0100140769            LQSNPILEAFGNAKTHRNDNSSRFGKYMDIEFDHKGAPVGGHILNYLLEKSRVVHQASGE
CG9155-RC               LKSNPVLEAFGNAKTNRNDNSSRFGKYMDIQFDFKGAPIGGNILNYLLEKSRVVAQMGGE
                        * * *:********* :************::**.:*..:**:**.********* *  **

ENST00000263078         RNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWKVVRKALTVI
ENSMUST00000057572      RNFHVFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWKVMRKALSVI
SINFRUP00000160392      RNFHIFYQLLDGADNNLLNQLDLERNPQKYQYLVKGNCPRISSVSDKNNWKAVMKALSVI
SINFRUP00000145776      RNFHIFYQLVEGGEEDLLRWLGLERNCKHYSYLVQGDCAKVSSINDKSDWKIVRKALSVI
ci0100140769            RNFHIFYQLLEGADEELLSRLMLQKTPDKYFYTSQGKCAKVSSINDRRDFLAVQKALKVL
CG9155-RC               RNFHIFYQLLAGADEALLQELRLERALDTYSYLTDGLNGTVTRINDADSFKQVQQALTVI
                        ****:****: *.::  *  * *::  . * *  .*    :: :.*  .:  : :**.*:

ENST00000263078         DFTEDEVEDLLSIVASVLHLGNIHFAANEESNAQVT--TENQLKYLTRLLSVEGSTLREA
ENSMUST00000057572      DFTEDEVEDLLSIVASVLHLGNIHFAADEDSNAQVT--TENQLKYLTRLLGVEGTTLREA
SINFRUP00000160392      GFTEEEVQNLLRIVGSILHLGNAQFGEGEGGETYIT--TEPEISTLAKLLAVDGSALGEA
SINFRUP00000145776      EFSESDIEDLFGIIASVLHLGNIKFDVDSEGYASLNNSSNNEMHWVSKLLGIPTEVLHRG
ci0100140769            EFSPKNIDELLSIVASVLHLGNVSFSANEEGHATVD--REHEIQKIANLLGCQFEQLLQA
CG9155-RC               DFTKEEQREIFGIVASILHLGNVGFT-EVEGNAKVN--SRDLVVTAARLLGVNASELEAA
                         *: .:  ::: *:.*:*****  *     . : :    .  :   :.**.     *  .

ENST00000263078         LTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSLASKDVESPSWR
ENSMUST00000057572      LTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVRKINRSLASKDAESPSWR
SINFRUP00000160392      LTHKKLKAKGEEVISPLSFEQALSARDALAKTVYRRTFNWLVEKINQSLAPKDELHRSSK
SINFRUP00000145776      LTHRKIEAKTEEVFSPFSEDHAVYARDALAKAVYGRTFNWLVNKINESLANKD----SSR
ci0100140769            LTHRTIEANKEKMESPLTVEQALYARDALSKAIYGRMFNWLVLKLNGSLTSKD-----RM
CG9155-RC               LTHRTIDARGDVVTSPLNQELAIYARDALAKAVYDRLFSWLVQRLNISLQAKET---RAS
                        ***:.: *. : : **:. : *  *****:*::* * *.*** ::* **  *:       

ENST00000263078         STTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYEAEGIAWEPVQ
ENSMUST00000057572      STTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYEAEGIAWEPVQ
SINFRUP00000160392      SSTLIGLLDIYGFEVLQCNSFEQFCINYCNEKLQQLFIELTLKSEQEEYETEGIAWETVK
SINFRUP00000145776      -KTVIGLLDIYGFEVFNVNSFEQFCINYCNEKLQQLFIQLTLKSEQEEYEMEGIEWEPVP
ci0100140769            RKNVIGLLDIYGFEIFKSNSFEQFCINFCNEKLQQLFIELTLKQEQEEYRAEGIEWEPVE
CG9155-RC               RNNVMGILDIYGFEIFQKNSFEQFCINFCNEKLQQLFIELTLKSEQDEYRREGIEWIPVE
                         ..::*:*******::: *********:**********:****.**:**. *** * .* 

ENST00000263078         YFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTVKHHPHFLTHKLADQR
ENSMUST00000057572      YFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTVKPHPHFLTHKLADQK
SINFRUP00000160392      YFDNKIICDLVEEKHKGIISILNEECLRPGETCDMSFLEKLEDTLGNHPH-ITHKLANGK
SINFRUP00000145776      YFNNKIICELVEAKHRGIISLLDEECLLPGEASDLTFLAKMEEKIGSHPHFVTHKLADQK
ci0100140769            YFNNKIICDLVEERHQGIIDILDEECLRPGEATDNTFLSKLEETVGKHPHFITHALGDSK
CG9155-RC               YFDNKVICNLIEEKHKGIISILDEECLRPGEPTDKTFLEKLTQKLAQHHHYVCHEKAPAH
                        **:**:**:*:* :.:***.:*:**** ***. * :** *: :.:  * * : *  .  :

ENST00000263078         TRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKNPIMSQCFDRSELS
ENSMUST00000057572      TRKSLDRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSMNPIMAQCFDKSELS
SINFRUP00000160392      TRRVMSREEFRLLHYAGEVNYNVNGFLDKNNNFLNRNLKEVMCKSDNQILRACFHREEAM
SINFRUP00000145776      TRKTLERGEFRLLHYAGEVSYSVVGFLDKNNDLLYRSGKEVMRQSKNAIIKLCFPSTESD
ci0100140769            MRKTIGYEEFRLVHYAGEVTYSVKGFLDKNNDLLYRDLKVTMSVSKNEIVKEAFPATELT
CG9155-RC               IKKIMLRDEFRLVHYAGEVTYSVNGFLDKNNDLLFRDLKETLSKAGNGIVRNCFPEKELR
                         :: :   ****:******.*.* *******::* *. * .:  : * *:  .*   *  

ENST00000263078         DKKRPE--TVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPGRFDEVLIRHQVKYLG
ENSMUST00000057572      DKKRPE--TVATQFKMSLLQLVEILRSKEPAYIRCIKPNDAKQPGRFDEVLIRHQVKYLG
SINFRUP00000160392      DQKRQEMVTAATNFKNSLMKLMEILMSKEPSYVRCIKPNDAKQPGKFDDVLVRHQVKYLG
SINFRUP00000145776      SKKRPE--TVVTQFKNSLTGLTEILLSKEPWYVRCIKPNEAKQPGRFDDVLVRHQVKYLG
ci0100140769            KLKRPE--TVGSQFRTSLNRLMDILMSKEPSYVRCIKPNDAKMADRFDETLVRHQVKYLG
CG9155-RC               SLKRPE--TAITQFRASLNNLMDILMCKEPSYIRCIKPNDLQTANVFNDELVLHQVKYLG
                        . ** *::*. ::*: **  * :** .*** *:******: : .. *:: *: *******

ENST00000263078         LLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGR--PQDGVAVLVRHLGYKPEEY
ENSMUST00000057572      LMENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPMWAGR--PQDGVAVLVRHLGYKPEEY
SINFRUP00000160392      LMENLRVRRAGFAYRRRFEAFLQRFKPLCPETWPNWHGR--LEDGVSTLVNHLGYKEEEY
SINFRUP00000145776      LMEHLRVRRAGFAYRRKYEVFLQRYKPLCPDTWPNWKGT--AAEGVKRLIVHLGYKRDEY
ci0100140769            LMENLRVRRAGFAYRRTHDIFLNRYKSLCPETWPHYDGP--SRKGVDVLCKYLDYKEGEY
CG9155-RC               LMENLRVRRAGFAYRRTYELFLERYKSLSKSTWPNYKGPGGPKAGVQQLVKDLGWDEEKY
                        *:*:************ .: **:*:*.*. .*** : *      **  *   *.:.  :*

ENST00000263078         KMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGFHWRQKFLRVKRSAICIQSWW
ENSMUST00000057572      KMGRTKIFIRFPKTLFATEDSLEVRRQSLATKIQAAWRGFHWRQKFLRVKRSAICIQSWW
SINFRUP00000160392      QLGRTKIFIRFPKTLFRTEDALQAKKPDIALILQTSWRGYRERSKYQRIRHAVIVIQSAW
SINFRUP00000145776      KMGRTKIFIRHPRTLFATEDAFQVCKHKLATRIQAKYKGYRMKGDYQRQREAATRIENCW
ci0100140769            RLGKTKVFIRFPRTLFATEDAFQIRKHELATTIQSVFRGWRQKKKFTTMRNAVTLLSSQW
CG9155-RC               RVGETKLFIRWPRTLFDTEDAYQEKKHEIAAIIQAHWKGLMQRRKYLKLRAQVIIMQSYC
                        ::*.**:*** *:*** ***: :  : .:*  :*: ::*   : .:   :  .  :..  

ENST00000263078         RGTLGRRKAAKRKWAAQTIRRLIRGFVLRHAPRCPENAFFLDHVRTSFLLNLRRQLPQNV
ENSMUST00000057572      RGTLGRRKAAKRKWAAQTIRRLIRGFILRHSPRCPENAFFLDHVRASFLLNLRRQLPRNV
SINFRUP00000160392      RGMKARRRAKTRRQAAELIRRFIKGFIYRHEEYCPENDYFLDHVRCSFLKKLRQNLPKSV
SINFRUP00000145776      RGLMARKEREKRAWAVKVIKRFIKGFITRNQPLCTDNSEYLAYVRYSYLTRLRENLPKTV
ci0100140769            KKILAQRLKAKRKKATLDIRKFILGFMTRLKPRCPENADFLDYVRYSYLMRAKESLPASV
CG9155-RC               RRKLAQQAAKKRREAADKIRAFIKGFITRNDAPNGFNEEFIANAKRMWLLRLAKELPTKV
                        :   .::   .*  *.  *: :* **: *       *  ::  .:  :* .  ..** .*

ENST00000263078         LDT-SWPTPPPALREASELLRELCIKNMVWKYCRSISPEWKQQLQQKAVASEIFKGKKDN
ENSMUST00000057572      LDT-SWPTPPPALREASELLRELCMKNMVWKYCRSISPEWKQQLQQKAVASEIFKGKKDN
SINFRUP00000160392      LDK-SWPTPPPSLVEASENLRNLHMRNMVIKYCKRVQPEWKKQMKQKVIASEIFKDQKDG
SINFRUP00000145776      LEKDSWLTPPPIMQEASQLLKKLYIRHMVRKYVGEVTPQRKAQLQLKLQTSSMFKGKKEN
ci0100140769            LDK-SWIHSPAALEETGKLLQQLNMKNLMLKYVKGVSPQRKAMMEEKVLASAIFRQKKKG
CG9155-RC               LDK-SWPHAPGHCEEASGILHRLHRLHLARIYRLKLTPQQKRQFELKVLAEKVFKGKKNN
                        *:. **  .*    *:.  *:.*   ::   *   : *: *  :: *  :. :*: :*..

ENST00000263078         YPQSVPRLFISTRLGTDEISPR---VLQALGS-EPIQYAVPVVKYDRKGYKPRSRQLLLT
ENSMUST00000057572      YPQSVPRLFISTRLGTEEISPR---VLQSLGS-EPIQYAVPVVKYDRKGYKPRPRQLLLT
SINFRUP00000160392      YPQTVGRLFLDTRLEPEQISLK---VLQTLGN-DKVQYGVPVTKYDRRGFKPRPRQLLLT
SINFRUP00000145776      YPFSVCRPFVDTRIGVEDINIK---VLQMIQH-EHIKYSVPVVKYDRNRFRPRLRQLVFT
ci0100140769            YDESVANPFQD-KPRVEQLKPK---MLATIDSGEQALYCCSVTKYDRHGYHPRARTLIIT
CG9155-RC               YASSVSTWFQEDRIPKEHIQRVNDFVASTFGS-EQLKYQSFCTKFDRHGYKSRDRFILLS
                        *  :*   * . :   :.:.     :   :   :   *    .*:**. ::.* * ::::

ENST00000263078         PNAVVIVE--DAKVKQRIDYANLTGISVSSLSDSLFVLHVQRADNKQKGDVVLQSDHVIE
ENSMUST00000057572      PSAVVIVE--DAKVKQRIDYANLTGISVSSLSDSLFVLHVQREDNKQKGDVVLQSDHVIE
SINFRUP00000160392      NTFAVLVD--RTKIKQRLDYSALRGISVSSLSDGVFVLHMPNEDSKQKGDVVLQCNYVIE
SINFRUP00000145776      QEAAYLVE--EAKIKQRISHSSLKGVSVSNLSDNFLILHVTCDDIKQKGDLVLQCDYLFE
ci0100140769            SGATYLFDSKDGKLKQKISHNELRGISTSSLGDNVFVLHAP-SDNKEKGDAIVQSTFVIE
CG9155-RC               NKAIYVLDGKTYKQKHRLPLDKID-FTLTNHNDDLMVIRIPLDLKKDKGDLILIIPRIIE
                             :.:    * *:::    :  .: :. .*..::::      *:*** ::    ::*

ENST00000263078         TLTKTALSANRVNSININ-QGSITFAGGPGRDGTIDFTPGSELLITKAKNGHLAVVAPRL
ENSMUST00000057572      TLTKTALSADRVNNININ-QGSITFAGGPGRDGIIDFTSGSELLITKAKNGHLAVVAPRL
SINFRUP00000160392      VVTKLGLMACKVNYVNVS-PGSVRFAVARGKEGIIDFVRGSELKVAKGKRGHLLV-----
SINFRUP00000145776      ALTKLSVIANKQKSIHVV-QGSARFDIHPGREGFVDFKSGQESTVYRAKNGHLMV-----
ci0100140769            TITKLARIAKKDQDVKIVDNSSILHDMTGGKQGRIDYVVGNEVSVTKTKTGLVVVAPAR-
CG9155-RC               FSTYIIDTVGTASIVSIVDRNSLEHNVVKGKGGVIDIQTGAEPGVVRDK-GHLVIIGTQ-
                          *     .   . : :   .*  .    *: * :*   * *  : : * * : :     

ENST00000263078         NSR
ENSMUST00000057572      NSR
SINFRUP00000160392      ---
SINFRUP00000145776      ---
ci0100140769            ---
CG9155-RC               ---