CLUSTAL W (1.82) multiple sequence alignment


ENSMUST00000021614      ------------------------------------------------------------
SINFRUP00000145013      ------------------------------------------------------------
ENST00000269848         ------------------------------------------------------------
ENSMUST00000020522      ------------------------------------------------------------
SINFRUP00000145340      ------------------------------------------------------------
SINFRUP00000162598      ------------------------------------------------------------
ci0100149716            ------------------------------------------------------------
CG4001-RA               MHSIKFRVFTKLKPIFLEINGRIPICRHFHGPTTFRLEISNKTPPIRQKLTFPNIGIQCT
                                                                                    

ENSMUST00000021614      ------------------------------------------------------------
SINFRUP00000145013      ------------------------------------------------------------
ENST00000269848         ------------------------------------------------------------
ENSMUST00000020522      ------------------------------------------------------------
SINFRUP00000145340      ------------------------------------------------------------
SINFRUP00000162598      ------------------------------------------------------------
ci0100149716            ------------------------------------------------------------
CG4001-RA               RSHHLCCPRDISGNTLLSVKFNCKRHCIKLRSDSGDQKNDSPGEKNIQKDKSAQRCGKPI
                                                                                    

ENSMUST00000021614      ------------------------------------MSDLDSSSSSAYPKYLEHLSGDGK
SINFRUP00000145013      -------------------------------------------ASS--------------
ENST00000269848         --------------------------------------------MRSMCNQGR---GRES
ENSMUST00000020522      --------------------------------------------MATVDLEKLRMSGAGK
SINFRUP00000145340      ------------------------------------------------------------
SINFRUP00000162598      ------------------------------------------------------------
ci0100149716            ------------------------------------MDHFNQMKRKLRKSVSSPLIGSGR
CG4001-RA               NNLHNGFLNAVNYSEKNAVKKKKSAPKRKCGKSVDELRKCLRTMQDVIDFVHPVKPFKDK
                                                            :                       

ENSMUST00000021614      AIGVLTSGGDAQGMNAAVRAVVRMG-IYTGAKVYFIY-EGYQGLVD--------------
SINFRUP00000145013      --------------------------------------QGYQGMVD--------------
ENST00000269848         SRGGLHVQGSCRGLSRSPQQETGFAKAPAGTDCFFHCSPGSRGQGDRKEEVTSEPGGTSI
ENSMUST00000020522      AIGVLTSGGDAQGMNAAVRAVTRMG-IYVGAKVFLIY-EGYEGLVE--------------
SINFRUP00000145340      ------------GMNAAVRAVTRMG-IYVGAKVYLIY-EGYQGLVD--------------
SINFRUP00000162598      --------------------------------------QGYQGLVD--------------
ci0100149716            CIAVFTSGGDSQGMNAAVRAIVRMG-ITCGAKVYLIH-EGYQGMVD--------------
CG4001-RA               GLAVFTSGGDSQGMNAAVRACVRMA-IYLGCKVYFIR-EGYQGMVD--------------
                            :        :         :          :    * .*  :              

ENSMUST00000021614      ----GGSNIVEAKWDCVSSILQVGGTIIGSARCKAFRSREGRLKAACNLARLGITNLCVI
SINFRUP00000145013      ----GGNNIKEATWESVSSMLQVGGTVIGSARCKEFRSREGRLKAAHNLVKRSINNLCVI
ENST00000269848         MSRLGGAVCRLPSLLKFLVSSVQGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVI
ENSMUST00000020522      ----GGENIKPANWLSVSNIIQLGGTIIGSARCKAFTTREGRLAAAYNLLQHGITNLCVI
SINFRUP00000145340      ----GGDNIKLAHWHSVTNIIQQGGTMIGSARCKAFTTREGRIAAAFNLVKKGITNLCVC
SINFRUP00000162598      ----GGDHIRPATWESVSMMLQLGGTVIGSARCQDFRTKEGRTKAALNLVKLGITNLCVV
ci0100149716            ----GGENIVEAAWDDVSGILQMGGTVIGSARCKDFREREGRLKAAFNLVTLGITNICAI
CG4001-RA               ----GGDCIQEANWASVSSIIHRGGTIIGSARCQDFRERQGRLKAANNLIQRGITNLVVI
                            **     .    .      ***:******: *  ::**  ** **   .*.*: . 

ENSMUST00000021614      GGDGSLTGANLFRKEWSGLLEELARNGDIDNDTVQKYSYLNVVGMVGSIDNDFCGTDMTI
SINFRUP00000145013      GGDGSLTGANLFREEWSGLLDELLKKGLIDEEEAQRNSELHIVGMVGSIDNDFCGTDMTI
ENST00000269848         GGDGSLTGANIFRSEWGSLLEELVAEGKISETTARTYSHLNIAGLVGSIDNDFCGTDMTI
ENSMUST00000020522      GGDGSLTGANIFRNEWGSLLEELVKEGKISESTAQNYAHLTIAGLVGSIDNDFCGTDMTI
SINFRUP00000145340      GGDGSLTGANIFRSEWSGLLAELVEKGRITDTLAKQHGHLNIVGLVGSIDNDFCGTDMTI
SINFRUP00000162598      GGDGSLTGANQFRTEWRDLLADLVKAGKVTSAEAKNSAHLNIVGMVGSIDNDFCGTDMTI
ci0100149716            GGDGSLTGANLFREEWSSLLQELVETGKINQEQATIHSHLNIVGLVGSIDNDFCGTDMTI
CG4001-RA               GGDGSLTGANLFRQEWSSLLDELVKNKTITTEQQEKFNVLHIVGLVGSIDNDFCGTDMTI
                        ********** ** ** .** :*     :          * :.*:***************

ENSMUST00000021614      GTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALTCGADWVFLPESPPE
SINFRUP00000145013      GTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFIPEMPPN
ENST00000269848         GTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPE
ENSMUST00000020522      GTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPE
SINFRUP00000145340      GADSALHRIMEIIDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPK
SINFRUP00000162598      GTDSALHRIIEIVDAITTTAQSHQRTFILEVMGRHCGYLALVTALACGADWVFIPEMPPE
ci0100149716            GADSALHRIVECVDAITTTAVSHQRAFVLEVMGRHCGYLALVTGLACGADWIFIPEHPPA
CG4001-RA               GTDTALHRIIEAIDAISSTAYSHQRTFIMEVMGRHCGYLALVGGLACEADFIFIPEMPPK
                        *:*:*****:* :*** :** ****:*::************* .*:. **::*:** ** 

ENSMUST00000021614      EDWEENMCLKLSENRARKKRLNIIIVSEGAIDMQNKPITSEKIKELVVKNLGFDTRVTIL
SINFRUP00000145013      DGWQDSMCQKLSGNRADKKRLNIIIVAEGAIDCHNKAITPDYIKDLVVSRLGFDTRVTIL
ENST00000269848         DGWENFMCERLGETRSRGSRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVL
ENSMUST00000020522      DGWENFMCERLGETRSRGSRLNIIIIAEGAIDRHGKPISSSYVKDLVVQRLGFDTRVTVL
SINFRUP00000145340      EGWEDRMCNRLEASRTTGSRLNIIIIAEGAIDMNGKPITSTYVKDLVVKRLGYDTRLTVL
SINFRUP00000162598      ENWEEHLCRRLTEQRGRGSRLNIIIVAEGAMDRHGTPITCEQVKQLVSKKLGFDTRTTIL
ci0100149716            DGWEEKMCGKLNNARSWGNRLNVVIVSEGAIDCHGNAITSQQVKEVICKRLDLDTRITVL
CG4001-RA               VDWPDRLCSQLAQERSAGQRLNIVIVAEGAMDREGHPITAEDVKKVIDERLKHDARITVL
                         .* : :* :*   *   .***::*::***:* .. .*:   :*.:: ..*  *:* *:*

ENSMUST00000021614      GHVQRGGTPSAFDRILA-SRMGVEAVIALLEATPETPACVVSLRGNQAVRLPLMECVQMT
SINFRUP00000145013      GHVQRGGTPSAFDRILA-SRMGVEAVLALLEASATTPACVVSLVGNQAVRLPLMECVQMT
ENST00000269848         GHVQRGGTPSAFDRILS-SKMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMT
ENSMUST00000020522      GHVQRGGTPSAFDRILS-SKMGMEAVMALLEATPDTPACVVSLSGNQSVRLPLMECVQVV
SINFRUP00000145340      GHVQRGGTPSAFDRTLS-SRLGVEAVIALMEATPDTPACVIGLSGNQAVRLPLMECVEMT
SINFRUP00000162598      GHVQRGGTPSAFDRILVKLKMGVEAVMALLEATPETPACVVSLSGNMAVRLPLMECVQVT
ci0100149716            GHVQRGGSPSAFDRLLG-TRMGAEAVLALLEATPETPAYVVSLDGNQAVRVPLMECVEKT
CG4001-RA               GHVQRGGNPSAFDRILA-CRMGAEATLALMEATKDSVPVVISLDGNQAVRVPLMECVERT
                        *******.****** *   ::* **.:**:**:  : . *: * ** :**:******: .

ENSMUST00000021614      QDVQKAMDERRFKEAVKLRGRRFEGNLNTYKRLAIKLPDEK------IVKSNCNVAVINV
SINFRUP00000145013      QEVQKAMDEKKFEEAVRLRGRSFENNLITYRLLSFRKTDSE------LPSSSFNVAVLNV
ENST00000269848         KEVQKAMDDKRFDEATQLRGGSFENNWNIYKLLAHQKPPKE--------KSNFSLAILNV
ENSMUST00000020522      KGWRRAGNG-----TVFFLSRSFENNWKIYKLLAHQKVSKE--------KSNFSLAILNV
SINFRUP00000145340      KLVQKCMNERRFDEAVKLRGGSFENNWNIYKLLAFQKPVKNEGKT--QVQTNFTLAILNV
SINFRUP00000162598      KDVTTAMAEGKFDEAIKLRGKSFENNWNTYRMLAHVHLPDT--------KSNINIALLNV
ci0100149716            KEVTKALAEKDFDRAASLRGRTFQGNLEIYKKLGAMSKAKEEATK--ILEKPYNVAIMNV
CG4001-RA               QAVAKAMAEKRWADAVKLRGRSFERNLETYKMLTRLKPPKENFDADGKGIEGYRLAVMHI
                        :    .        :  : .  *: *   *: *      .              :*::::

ENSMUST00000021614      GAPAAGMNAAVRSAVRVGIADGHKMFAIYDGFEGFANGQIKEIGWADVGGWTGQGGSILG
SINFRUP00000145013      GAPAAGMNAAVRSAVRVGIAEGHRMFAVNDGFEGLSKGQIKEIKWGDVGGWTGQGGSLLG
ENST00000269848         GAPAAGMNAAVRSAVRTGISHGHTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLG
ENSMUST00000020522      GAPAAGMNAAVRSAVRTGISEGHTVYLVHDGFEGLAPGQVGVVVMYVVSGLVGRGGSFPG
SINFRUP00000145340      GAPAAGMNSAVRSAVRLALIHGHKVYGVHDGFQGLAKGELFKMNWGNVAGWTGQGGSLLG
SINFRUP00000162598      GAPCAGMNAVVRSAVRIGILQGHQMLAVHDGFDGLAQGMIEPIGWSGVAGWTGKGGSFLG
ci0100149716            GAPAAGMNAAVRSAVRTCLYNGYKALVVHNGYEGLANDMVETYTWKCVANFVAAGGSKLG
CG4001-RA               GAPACGMNAAVRSFVRNAIYRGDVVYGINDGVEGLIAGNVRELGWSDVSGWVGQGGAYLG
                        ***..***:.*** **  :  *     : :* :*:  . :       *..  . **:  *

ENSMUST00000021614      TKRTLPGKY-LEKIAEQMHSHSINALLIIGGFEAYLGLLELAAAREKHEAFCVPMVMVPA
SINFRUP00000145013      TKRTLPAKH-LEEIANQFRIHNINALLVIGGFEAYMGLLELSSARD-YDEFCVPMVMVPA
ENST00000269848         TKRTLPKGQ-LESIVENIRIYGIHALLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPA
ENSMUST00000020522      TKRTLPKPH-LEAIVENLRTYNIHALLVIGGFEAYEGVLQLVEARGRYEELCIVMCVIPA
SINFRUP00000145340      TKRTLPEEH-MENVVETIRKYKISALLVIGGFEGYEGVLQLFEARTHYEELCIPMCVVPA
SINFRUP00000162598      TKRSLPQEV-MEEISLNIAKFNIHAMVIIGGFEAFVGGLQMVQAREKYEELCIPIVVVPA
ci0100149716            TKRTLPSQCGFDKISEIINKRNIHGIICIGGFEAVQGAMEFEEGRKNYPELQIPLVCIPC
CG4001-RA               TKRTLPEGK-FKEIAARLKEFKIQGLLIIGGFESYHAAGQIADQRDNYPQFCIPIVVIPS
                        ***:**    :. :   :    * .:: :****.  .  ::   *  :  : : :  :*.

ENSMUST00000021614      TVSNNVPGSDFSIGADTALNTITDTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGALA
SINFRUP00000145013      TVSNNVPGSDLSIGSDTALNAITDTCDRIKQSASGTKRRVFIIETMGGYCGYLATVGGLA
ENST00000269848         TISNNVPGTDFSLGSDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIA
ENSMUST00000020522      TISNNVPGTDFSLGSDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIA
SINFRUP00000145340      TISNNVPGTDFSLGADTAVNSVMDCCDKIKQSASGTKSRVFVVETMGGYSGYLATTAGIA
SINFRUP00000162598      TVSNNIPGSDFSVGADTALNTITMTCDRIKQSAAGTKRRVFIVETMGGHCGYLATMAGLA
ci0100149716            TVSNNIPGSDLSIGTDTALNMIVETCDRIKMSASGTKRRTFVLETMGGYCGYLATMSGLA
CG4001-RA               TISNNVPGTEFSLGCDTGLNEITEICDRIRQSAQGTKRRVFVIETMGGYCGYLATLAGLA
                        *:***:**:::*:* **.:*     **:*: ** *** *.*::*****:.****.  .:*

ENSMUST00000021614      AGADAAYIFEEPFDIGDLQSNVVHLTEKMKTSIQRGLVLRNESCSVNYTTDFIYQLYSEE
SINFRUP00000145013      AGADTVYIHEEPFDIRDLQANVEHLTEKMKTSIQRGLVLRNENCNKNFTTDFIYQLYSEE
ENST00000269848         VGADAAYVFEDPFNIHDLKVNVEHMTEKMKTDIQRGLVLRNEKCHDYYTTEFLYNLYSSE
ENSMUST00000020522      VGADAAYVFEDPFNIHDLKANVEHMTEKMKTDIQRGLVLRNEKCHEHYTTEFLYNLYSSE
SINFRUP00000145340      TGADAVYIYEDPFNIHDLTTNVEHLTEKMKKDVQRGLVLRNEKCHEFYTTDFIHKLYSAE
SINFRUP00000162598      SGADAAYIYEEPFKIRDLEMNVEHLVEKMKTTVKRGLILRNERCNANYTTDFIYNLYAEE
ci0100149716            AGADAAYIFEEEFTIKDLQKNIYHLRNKMKGKIQRGLILRNEKANDNFSTDFVHRLYAEE
CG4001-RA               GGADAAYIYEEKFSIKDLQQDVYHMASKMAEGVSRGLILRNEKASENYSTDFIYRLYSEE
                         ***:.*:.*: * * **  :: *: .**   :.***:**** .   ::*:*::.**: *

ENSMUST00000021614      GKGVFDCRKNVLGHMQQGGAPSPFDRNFGTKISAKAMEWISAKLKGSQGT-GKKFVSD-D
SINFRUP00000145013      GRGVFDCRKNILGHMQQGGAPSPFDRNFSTKIAAKAIQWISQKLTDCYKG-GKRSRR---
ENST00000269848         GKGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKAMLWLSEKLREVYRK-GRVFANAPD
ENSMUST00000020522      GRGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKAMLWVSEKLRDVYRK-GRVFANAPD
SINFRUP00000145340      GKGIFDCRFNVLGHLQQGGAPSPFDRNFGTKLGVRAIQWLSQKLSENFRQ-DHVFANSSD
SINFRUP00000162598      GKGVFDCRKNVLGHMQQGGTPSPFDRNFGTKMGMKSVLWLTDKLKECYRH-GRIFANSPD
ci0100149716            GKNVFDCRVNVLGHMQQGGVPSPFDRNYATKSAAKAAFWILDKIENNLVD-GKVVCNSQD
CG4001-RA               GKGLFTCRMNILGHMQQGGSPTPFDRNMGTKMAAKCVDWLAAQIKANIDANGVVNCKSPD
                        *:.:* ** *:***:**** *:***** .** . :.  *:  ::       .        

ENSMUST00000021614      SICVLGICKRDLLFQPVAELKKVTDFEHRIPKEQWWLKLRPIMKILAKYEASYDMSDSGK
SINFRUP00000145013      ------------LLGRAAGLLTDAGFVHRVPRDQWWLKLRPVMKILAKYKTSYDVSDAGQ
ENST00000269848         SACVIGLKKKAVAFSPVTELKKDTDFEHRMPREQWWLSLRLMLKMLAQYRISMAAYVSGE
ENSMUST00000020522      SACVIGLRKKVVAFSPVTELKKETDFEHRMPREQWWLNLRLMLKMLAHYRISMADYVSGE
SINFRUP00000145340      TACVLGFSRKVISFIPVTELKAMTDFEHRMPKEQWWLKFRPILKMLAKYQISFCEYVPGE
SINFRUP00000162598      SACVLGMKKRALVFTSLAELKDQTDFEHRIPKTQWWIKLRPILKILAKYKINLDMTEKTT
ci0100149716            SVVLLGMRRRQMLFQPVEDLKADTDFKHRIPNQQWWMQIRPLLRIMAHYQDETAVYESDV
CG4001-RA               TATLLGIVSRQYRFSPLVDLIAETNFDQRIPKKQWWLRLRPLLRILAKHDSAYEEEGMYI
                           :: :      :     *   :.* :*:*. ***: :* :::::*::           

ENSMUST00000021614      LESLQHHEEL-----
SINFRUP00000145013      LEHV-----------
ENST00000269848         LEHVTRRTLSMDKGF
ENSMUST00000020522      LEHVTRRTLSIDKGF
SINFRUP00000145340      IEHVTRRSISIDSVF
SINFRUP00000162598      MEHVIKKR-------
ci0100149716            ---------------
CG4001-RA               TVEEECDTDAVA---