CLUSTAL W (1.82) multiple sequence alignment


SINFRUP00000131848      ------------------------------------------------------------
ENST00000264608         ------------------------------------------------------------
SINFRUP00000141941      ------------------------------------------------------------
ENSMUST00000018429      ------------------------------------------------------------
CG12110-RA              MADAGTVGGALPPYALTNSDEEHGSGEEDASEENSNNEEGEGVFRDCTDEAVVEHHNRCL
                                                                                    

SINFRUP00000131848      ------------------------MADLVESLDTRELDIGDGEDLDYDAN----SLGDCR
ENST00000264608         ----MSLKNEPRVNTSALQKIAADMSNIIENLDTRELHFE-GEEVDYDVSPSDPKIQEVY
SINFRUP00000141941      ------------------------------------------------------------
ENSMUST00000018429      -----------------MTVTQKNLFPYGDYLNSSQLHMEPDEVDTLREGE---DPADRM
CG12110-RA              PEFQFSLVDSEYDETLAFPDSVTILSNVGDKPVLVERKETDDDEEEFDDEENNSVVLRHE
                                         :      :                                   

SINFRUP00000131848      IQFSAVYA-TVGFKEASAKVYLPTVPITARILEMERFTTAQ-----DLFKIELKHGEFTW
ENST00000264608         IPFSAIYN-TQGFKEPNIQTYLSGCPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKW
SINFRUP00000141941      ----------------------------------------------TLYTVRLTHGPFHW
ENSMUST00000018429      HPYLAIYD-LQPLK-AHPLVFAPGVPVIAQVVGTERYTSGSKVGTCTLYSVRLTHGDFTW
CG12110-RA              IPFTSIYGPSVKFNSFQRKVFIPGREIHVRIVDTERSVTTHLLNP-NLYTIELTHGPFKW
                             :      :             :   ::          :    *:.:.*.** * *

SINFRUP00000131848      LIKRKEKHFMELHRELRTYKTFIRIPLPSRRLASVSRLCHMTGTSVSLT-----------
ENST00000264608         QVKRKFKHFQEFHRELLKYKAFIRIPIPTRRHT--FRRQNVREEPREMP-----------
SINFRUP00000141941      TVKRKYKHFQELHRDLYKHKMMIHLLPLSRFTK---DRQQLRAMSEEMP-----------
ENSMUST00000018429      TTKKKFRHFQELHRDLQRHKVLMSLLPLARFAVT--HSPAREAAAEDIP-----------
CG12110-RA              TIKRRYKHFNSLHQQLSFFRTSLNIPFPSRSHKE--KRTTLKATAREMADESTLKDLPSH
                          *:: :** .:*::*  .:  : :   :*              . .:.           

SINFRUP00000131848      ---------------------------------------------------------SVA
ENST00000264608         ---------------------------------------------------------SLP
SINFRUP00000141941      ---------------------------------------------------------SLQ
ENSMUST00000018429      ---------------------------------------------------------SLP
CG12110-RA              TKVKQTSTPLRAEGRSSKIAGSNANNAMAMISPNHSSILAGLTPRRIQKKRKKKKKRKLP
                                                                                 .: 

SINFRUP00000131848      H---QTQHAKSLCVFM-----LTWFWTADSNIPCLH-FLSAMEFIDVSQLSFIHDLGPKG
ENST00000264608         R---SSENMIREEQFLGRRKQLEDYLTKILKMPMYRNYHATTEFLDISQLSFIHDLGPKG
SINFRUP00000141941      G---TERTRRTSSKMK----YLEEYLNGLLENVFCRNDHSMLEFLSVGALSFVTDLGPKG
ENSMUST00000018429      RG-GSEGSARHTASKQ---KYLENYLNRLLTMSFYRNYHAMTEFLEVSQLSFIPDLGSKG
CG12110-RA              RFPNRPESLVTVENLSVRIKQLEDYLYNLLNISLYRSHHETLNFVEVSNVSFVPGMGIKG
                                             *  :          :      :*:.:. :**: .:* **

SINFRUP00000131848      LEGLIYKRSGGHR--IPGMNCCGQNQ--------------VCYRWSKRWLVVKDSCLIYM
ENST00000264608         IEGMIMKRSGGHR--IPGLNCCGQGR--------------ACYRWSKRWLIVKDSFLLYM
SINFRUP00000141941      LEGPIFKRSGGHR--IQGLNCFGHHQ--------------FCFRWSRRWLVVKDSFLMYM
ENSMUST00000018429      LEGVIRKRSGGHR--VPGFTFCGRDQ--------------VCYRWSKRWLVVKDSFLLYM
CG12110-RA              KEGVILKRTGSTRPGQAGCNFFGCFQKNCCVRCNYFCSDVVCGTWRNRWFFVKETCFGYI
                         ** * **:*. *    * .  *  :               *  * .**:.**:: : *:

SINFRUP00000131848      KPDSGAISFVLLLDKEFTIKMDSKDTETKHGVRIDSLSRTLVFKCSSYRHARWWGQSIES
ENST00000264608         KPDSGAIAFVLLVDKEFKIKVGKKETETKYGIRIDNLSRTLILKCNSYRHARWWGGAIEE
SINFRUP00000141941      NRDYGRINFVLLFDKEFKVKVGRAYTDTKYGVCFENFTRSLVIKCSSYRQAHWWSHEINQ
ENSMUST00000018429      RPETGAISFVQLFDPGFEVQVGKRSTETRYGVRIDTSHRSLILKCSSYRQARWWGQEITE
CG12110-RA              RPTDGSIRAVILFDQGFDVSTGIYQTGMRKGLQVLTNNRHIVLKCWTRRKCKEWMQYLKN
                        .   * *  * *.*  * :. .   *  : *: . .  * :::** : *:.: *   : .

SINFRUP00000131848      FVRSHGKAFLRDHRFGSFAQEQENIPAKWYVNGKTYMEDVANALEEAKEEIFITDWWLSP
ENST00000264608         FIQKHGTNFLKDHRFGSYAAIQENALAKWYVNAKGYFEDVANAMEEANEEIFITDWWLSP
SINFRUP00000141941      LAETC--DFLKEHRFDGFAPPRENMLTKWYVNGRDYFADLADALDQAKEEIYITDWWLSP
ENSMUST00000018429      LAQGSGRDFLQLHQHDSYAPPRPGTLARWFVNGAGYFAAVADAILRAQEEIFITDWWLSP
CG12110-RA              TANSYARDFTLPNPHMSFAPMRANTHATWYVDGAQYMSAVADGLEAALEEIYIADWWLSP
                          .     *   : . .:*  : .  : *:*:.  *:  :*:.:  * ***:*:******

SINFRUP00000131848      EIFLKRPVVEGNRWRLDCILKRKAQQGVRIFVMLYKEVELALGINSGYSKRTLLHLHPNI
ENST00000264608         EIFLKRPVVEGNRWRLDCILKRKAQQGVRIFIMLYKEVELALGINSEYTKRTLMRLHPNI
SINFRUP00000141941      EVFLKRPATD-NYWRLDTILKRKAEQGIKVCILLYKEVELALGINSEHSKRTLMNMHPNI
ENSMUST00000018429      EIYLKRPAHS-DDWRLDIMLKRKAEEGVRVSILLFKEVELALGINSGYSKRTLMLLHPNI
CG12110-RA              EIYMKRPALDGDYWRLDKILLRKAEQGVRVFVLLYKEVEMALGINSYYSKSTLAK-HENI
                        *:::***. . : **** :* ***::*::: ::*:****:****** ::* **  :* **

SINFRUP00000131848      KVMRHPDHVSSSVYLWAHHEKIVVVDQSVAFVGGIDLAYGRWDDREHRLTDVGSAGRANA
ENST00000264608         KVMRHPDHVSSTVYLWAHHEKLVIIDQSVAFVGGIDLAYGRWDDNEHRLTDVGSVKRVTS
SINFRUP00000141941      KVMRHPDHVSSVVFLWAHHEKMVAIDQTVAFVGGIDLAFGRWDDFEYRLTDLG-------
ENSMUST00000018429      KVMRHPDLVT----LWAHHEKLLVVDQVVAFLGGLDLAFGRWDDVQYRLTDLGD------
CG12110-RA              KVMRHPDHARGGILLWAHHEKIVVIDQTYAFMGGIDLCYGRWDDHHHRLTDLGSISTSSF
                        ******* .     *******:: :**  **:**:**.:***** .:****:*       

SINFRUP00000131848      LPGKGAPPSGGVSESN-----GRGTPPSDLAELP-------------------KLKGIGR
ENST00000264608         GPSLGSLPPAAMESMESLRLKDKNEPVQNLPIQKSIDDVDS------------KLKGIGK
SINFRUP00000141941      ------LPPEGVTKEE--------------------------------------------
ENSMUST00000018429      -------PSEPVHLQT--------------------------------------------
CG12110-RA              SGSTRRTPSLYFTKDDTDSAFGSRKSSRNAHYDTSAKERPPSPPPDEPNTSIELKTLKPG
                               *.  .                                                

SINFRUP00000131848      NRR-TRFSLYRHLQKHAMQHSDSVDSVDSTGS----------------------------
ENST00000264608         PRKFSKFSLYKQLHRHHLHDADSISSIDSTSSYFNHYRSHHNLIHGLKPHFKLFHPSSES
SINFRUP00000141941      ------------------PEGDTVD-----------------------------------
ENSMUST00000018429      ----------------PTLGSDP-------------------------------------
CG12110-RA              DRLLIPSTLVSSPGETPAESGIALEGMKLNTPEMERKNVLDRLKNNAMKGARMGKDFMHR
                                            . .                                     

SINFRUP00000131848      -----------GSVRSLKTDVGELQGNTRFWHG-----KDYCNFVYKDWIQLEKPFDDFI
ENST00000264608         EQGLTRPHADTGSIRSLQTGVGELHGETRFWHG-----KDYCNFVFKDWVQLDKPFADFI
SINFRUP00000141941      -----------------KEDPLDLIGNSKLWLG-----KDYSNFIRKDWVQLDRPFEDNI
ENSMUST00000018429      ------------------AATPDLSHNQFFWLG-----KDYSNLITKDWVQLDRPFEDFI
CG12110-RA              LTATETEEKSAEVYTIESEEATDHEVNLNMASGGQEVAITTSSTQILNWMNLNSPFVDII
                                              :   :  :  *        ..    :*::*: ** * *

SINFRUP00000131848      DRYTTPRMPWHDIASAVHGRAARDVARHFIQRWNFTKIMKPKYRSLSYPFLLPKSHSTAN
ENST00000264608         DRYSTPRMPWHDIASAVHGKAARDVARHFIQRWNFTKIMKSKYRSLSYPFLLPKSQTTAH
SINFRUP00000141941      DRAEVPRMPWRDLSAAVHGKAARDVARHFIQRWNFTKVRR-RFKKQIFLHLFS-------
ENSMUST00000018429      DRETTPRMPWRDVGVVVHGVAARDLARHFIQRWNFTKTTKARYKTPLYPYLLPKSTSTAN
CG12110-RA              DRTTTPRMPWHDVGLCVVGTSARDVARHFIQRWNAMKLEKLRDNTR-FPYLMPKSYHQVR
                        **  .*****:*:.  * * :***:*********  *  : : ..  : .*:.       

SINFRUP00000131848      ELRYQIPDCV-TAKVQVLRSAADWSAGIKY---HEESIHNAYVQVIAKSKHYIYIENQFF
ENST00000264608         ELRYQVPGSV-HANVQLLRSAADWSAGIKY---HEESIHAAYVHVIENSRHYIYIENQFF
SINFRUP00000141941      ----SYFECQ-CRVCPVLRSADHWSTGT-----CENSILKAYIHTIENSEHFIYIENQFF
ENSMUST00000018429      NLPFMIPGGQ-CATVQVLRSVDRWSAGT-----LENSILNAYLHTIRESQHFLYIENQFF
CG12110-RA              LNPNIQQNRQQRVTCQLLRSVSAWSCGFIEADLVEQSIHDAYIQTITKAQHYVYIENQFF
                                        :***.  ** *       *:**  **::.* ::.*::*******

SINFRUP00000131848      ISCAESR-------LVYNKIGDAIIERIIRAHKEGRKYRVYVVTPLLPGFEGDITTGGGN
ENST00000264608         ISCADDK-------VVFNKIGDAIAQRILKAHRENQKYRVYVVIPLLPGFEGDISTGGGN
SINFRUP00000141941      ISCADEK-------TVYNEIGDAIVNRILRAHREQKKYRVFVVIPLLPGFEGDISEGGGN
ENSMUST00000018429      ISCSDGR-------TVLNKVGDEIVDRILKAHEQGQCFRVYLLLPLLPGFEGDISTGGGN
CG12110-RA              ITMQLGMGVPGAYNNVRNQIGETLFKRIVRAHKERKPFRVYVIMPLLPGFEGDVGGSTGI
                        *:             * *::*: : .**::**.: : :**::: *********:  . * 

SINFRUP00000131848      AIQAVMHFNYRTMIRGEHSIISQLKKEMDDQWMNYISFAGLRTHTELEGRLVTELIYVHS
ENST00000264608         ALQAIMHFNYRTMCRGENSILGQLKAELGNQWINYISFCGLRTHAELEGNLVTELIYVHS
SINFRUP00000141941      AIKAILHFTYR-------------------------------------------------
ENSMUST00000018429      SIQAILHFTYRTLCRGEHSILHRLKAAMGTAWRDYMSICGLRTHGELGGHPISELIYIHS
CG12110-RA              AVRAITHWNYASISRGRTSILTRLQEAGIANPENYISFHSLRNHSFLNNTPITELIYVHS
                        :::*: *:.*  :      ::  :           : :  :     :    :  :: :  

SINFRUP00000131848      KMLIADDNTVIIGSANINDRSMLGKRDSEVAVIVEDSEKVAAVMDGREYEAGPYALQLRL
ENST00000264608         KLLIADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVPSVMDGKEYQAGRFARGLRL
SINFRUP00000141941      ------------------------------------------------------------
ENSMUST00000018429      KMLIADDRTVIIGSANINDRSLLGKRDSELAILIKDTEMEPSLMDGVEYQAGRFALSLRK
CG12110-RA              KLLIADDRVVICGSANINDRSMIGKRDSEIAAILMDEEFEDGRMNGKKYPSGVFAGRLRK
                         :::     ::     :    ::      :  ::         :             :  

SINFRUP00000131848      ECFRTILGGH-----SDTSIDLSDPVSDRFYKEVWMTTAGRNATIYEKVFRCLPSSLVRN
ENST00000264608         QCFRVVLGYL-----DDPSEDIQDPVSDKFFKEVWVSTAARNATIYDKVFRCLPNDEVHN
SINFRUP00000141941      ------------------------------------------------------------
ENSMUST00000018429      HCFSVILGAN-----TWPDLDLRDPVCDDFF-QLWQETAENNATIYEQIFRCLPSNATRS
CG12110-RA              YLFKEHLGLLESEGSSRSDLDINDPVCEKFWHGTWRRISMQNTEIYDEVFKCIPTDFVKT
                          :   :              :   :   :              :   ::  :       

SINFRUP00000131848      MSELEQYQSILGLAQTDQARAQEELRKIHGFLVQFPLDFLSEQNLMPSVGTKEAMVPTEI
ENST00000264608         LIQLRDFINKPVLAKEDPIRAEEELKKIRGFLVQFPFYFLSEESLLPSVGTKEAIVPMEV
SINFRUP00000141941      ------------------------------------------------------------
ENSMUST00000018429      LRALREYVAVESLATVSPSLAQSELAHIQGHLVHFPLKFLEDESLLPPLGSKEGMIPLEV
CG12110-RA              FASLRKYQEEPPLAKTAPDLAANRANDIQGYLVDLPLEFLNKEVLTPPGTSKEGLIPTSV
                        :  :        :              :   :: : : ::    :         ::   :

SINFRUP00000131848      WT
ENST00000264608         WT
SINFRUP00000141941      --
ENSMUST00000018429      WT
CG12110-RA              WT