CLUSTAL W (1.82) multiple sequence alignment


ENST00000261412         MEYEWKPDEQGLQQILQLLKESQSPDTTIQRTVQQK----------LEQLNQYPDFNNYL
ENSMUST00000040075      MEYEWKPDEQGLQQILQLLKESQSPDTTIQR---TK----------LEQLNQYPDFNNYL
SINFRUP00000155284      MECEWKPDEQGLQQILQLLKESQSPDTSTQRTVQQR----------LEQLNQYPDFNNYL
SINFRUP00000137496      ---EWQPDEQGLQQVLQLLKDSQSPDTATQRAVQEK----------LEQLNQFPDFNNYL
SINFRUP00000156613      --MEWQPDEQGLMQVLQLLKDSQSPNTVTQRAVQQVSLLGSLTVLKLEQLNQFPDFNNYL
ENST00000222183         --MDWQPDEQGLQQVLQLLKDSQSPNTATQRIVQDK----------LKQLNQFPDFNNYL
ENSMUST00000005288      --MDWQPYEQGLQQVLQLLKDSQSPNTATQRIVQDK----------LKQLNQFPDFNNYL
CG7398-RA               --MTWEPQGEGLQQIIAILKESQSPDTATQMAVQMK----------LEEFNRYPDFNNYL
                            *:*  :** *:: :**:****:*  *  :             *:::*::*******

ENST00000261412         IFVLTKLKSEDEPTRSLSGLILKNNVKAHFQNFPNGVTDFIKSECLNNIGDSSPLIRATV
ENSMUST00000040075      IFVLTKLKSEDEPTRSLSGLILKNNVKAHFQNFPNGVTDFIKSECLNNIGDSSPLIRATV
SINFRUP00000155284      IFVLTKLKSEDEPTRSLSGLILKNNVKAHYQNFPNGVSDFIKSECLQNIGDSSPLIRATV
SINFRUP00000137496      IFVLTSLKSEDEPTRSLSGLILKNNVKAHYQSFPPNVADFIKRECLNNIGDPSPLIRATI
SINFRUP00000156613      IFVLTRLKSEDEPTRSLSGLILKNNVKAHYQNFPSGVSDFIKHECLNNIGDASLLIRATI
ENST00000222183         IFVLTRLKSEDEPTRSLSGLILKNNVKAHYQSFPPPVADFIKQECLNNIGDASSLIRATI
ENSMUST00000005288      IFVLTRLKSEDEPTRSLSGLILKNNVKAHYQSFPPPVADFIKQECLNNIGDASSLIRATI
CG7398-RA               IYVLTKLKTEDEPTRSLSGLILKNNIRMHGTTLQPEIVEYIKHECLQAVGDASPLIRATV
                        *:*** **:****************:: *  .:   : ::** ***: :**.* *****:

ENST00000261412         GILITTIASKGELQNWPDLLPKLCSLLDSEDYNTCEGAFGALQKICEDSAEILDSDVLDR
ENSMUST00000040075      GILITTIASKGELQNWPDLLPKLCSLLDSEDYNTCEGAFGALQKICEDSAEILDSDVLDR
SINFRUP00000155284      GILITTIASKGELQNWPELLPKLCLLLDSEDYNTCEGAFGALQKICEDSAEILDSDILDR
SINFRUP00000137496      GILITTIASKGELQTWPELLPQLCNLLNSEDYNTCEGSFGALQKICEDSSELLDSEALNR
SINFRUP00000156613      GILITTIASKGELQTWPELLPQLCSLLDSEDYNTCEGSFGALQKICEDSSELLDSDALNQ
ENST00000222183         GILITTIASKGELQMWPELLPQLCNLLNSEDYNTCEGAFGALQKICEDSSELLDSDALNR
ENSMUST00000005288      GILITTIASKGELQMWPELLPQLCNLLNSEDYNTCEGAFGALQKICEDSSELLDSDALNR
CG7398-RA               GILITTIASNGGLHNWPQLLPSLCEMLDNQDYNVCEGAFSALQKICEDSAEILDSAALNR
                        *********:* *: **:***.** :*:.:***.***:*.*********:*:***  *::

ENST00000261412         PLNIMIPKFLQFFKHSSPKIRSHAVACVNQFIISRTQALMLHIDSFIEN---LFALAGDE
ENSMUST00000040075      PLNIMIPKFLQFFKHSSPKIRSHAVACVNQFIISRTQALMLHIDSFIEN---LFALAGDE
SINFRUP00000155284      PLNFMIPKFLQFFKHNSPKIRSHAIACVNQFIISRTQALMLHIDPFIEASLNLFALAEDE
SINFRUP00000137496      PLNIMIPKFLQFFKHCSPKIRSHAIACVNQFIIGRAQALMDNIDTFIES---LFALAGDE
SINFRUP00000156613      PLNIMIPKFLQFFKHRSPKIRSHAIACVNQFIICRAQALMDNIDTFIES---LFALAADE
ENST00000222183         PLNIMIPKFLQFFKHCSPKIRSHAIACVNQFIMDRAQALMDNIDTFIEH---LFALAVDD
ENSMUST00000005288      PLNIMIPKFLQFFKHCSPKIRSHAIACVNQFIMDRAQALMDNIDTFIEH---LFALAVDD
CG7398-RA               PLNIMIPKFLEYFKHSSPKIRSHAIACINQFIINRSQALMLNIDSFIEN---LFHLSSDE
                        ***:******::*** ********:**:****: *:**** :**.***    ** *: *:

ENST00000261412         EPEVRKNVCRALVMLLEVRMDRLLPHMHNIVEYMLQRTQDQDENVALEACEFWLTLAEQP
ENSMUST00000040075      EAEVRKNVCRALVMLLEVRMDRLLPHMHNIVEYMLQRTQDQDENVALEACEFWLTLAEQP
SINFRUP00000155284      EPEVRKNVCRALVMLLEVRLDRLLPHMHNIIEYMLQRTQDQDENVALEACEFWLTLAEQP
SINFRUP00000137496      DSEVRKNVCRALVMLLEVRIDRLIPHMHSIIQYMLQRTQDPDENVALEACEFWLTLAEQP
SINFRUP00000156613      DSEVRKNVCRALVMLLEVRIDRLIPHMHSIIQYMLQRTQDPDENVALEACEFWLTLAEQP
ENST00000222183         DPEVRKNVCRALVMLLEVRIDRLIPHMHSIIQYMLQRTQDHDENVALEACEFWLTLAEQP
ENSMUST00000005288      DPEVRKNVCRALVMLLEVRIDRLIPHMHSIIQYMLQRTQDHDENVALEACEFWLTLAEQP
CG7398-RA               DHEVRKNVCHGLVMLLEVRMDRLMPHMSQIIEYMLLRTQDTDEGVALEASEFWLSLAEQS
                        : *******:.********:***:*** .*::*** **** **.*****.****:****.

ENST00000261412         ICKDVLVRHLPKLIPVLVNGMKYSDIDIILLKGDVEEDETIPDSEQDIRPRFHRSR--TV
ENSMUST00000040075      ICKDVLVRHLPKLIPVLVNGMKYSDIDIILLKGDVEEDETIPDSEQDIRPRFHRSR--TV
SINFRUP00000155284      VCKEVLCGHLSKLTPVLVNGMKYSEIDIILLKGDIEEDEAIPDNEQDIRPRFHRSR--TV
SINFRUP00000137496      ICKEALSGHLVQLIPILVNGMKYSEIDIILLKGDVEEDEAIPDSEQDIKPRFHKSR--TV
SINFRUP00000156613      ICKEMLSGHLVQLVPILVNGMKYSEIDIILLKGDVEEDEAVPDSDQDIKPRFHKSR--TV
ENST00000222183         ICKEVLASHLVQLIPILVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIKPRFHKSR--TV
ENSMUST00000005288      ICKEVLASHLVQLIPILVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIKPRFHKSR--TV
CG7398-RA               ICKDVLAPYLAQLAPVLVRGMRYSEVDIILLKGNVEEDDMVPDREEDIRPRFHKSRAHTI
                        :**: *  :* :* *:**.**:**::*******::***: :** ::**:****:**  *:

ENST00000261412         AQQHDEDGIEEEDDDDDEIDDDD----TISDWNLRKCSAAALDVLANVYRDELLPHILPL
ENSMUST00000040075      AQQ-------------------------------RKCSAAALDVLANVYRDELLPHILPL
SINFRUP00000155284      AQQH---------------------------WNLRKCSAAALDVLANVFRDELLLHILPL
SINFRUP00000137496      TLQHEGGEGEEGEDINVTSEHNVNRKILMYSRPPGKCSAAALDVLANVFRDELLPHLLPL
SINFRUP00000156613      TLQHEGGGDEEDEDI-------------------GKCSAAALDVLANVFRDDLLPHLLPV
ENST00000222183         TLPHEAERPDGSEDAEDDDDDD-----ALSDWNLRKCSAAALDVLANVFREELLPHLLPL
ENSMUST00000005288      TLTHEAERPDSSEDAEDDDDDD-----ALSDWNLRKCSAAALDVLANVFREELLPHLLPL
CG7398-RA               RSTQEGGAGATGDDDDDEFEDGMDDDSSLSEWNLRKCSAAALDVLANVFREDCLPVVLPI
                                                    :      *************:*:: *  :**:

ENST00000261412         LKELLFHHEWVVKESGILVLGAIAEGCMQGMIPYLPELIPHLIQCLSDKKALVRSITCWT
ENSMUST00000040075      LKELLFHHEWVVKESGILVLGAIAEGCMQGMIPYLPELIPHLIQCLSDKKALVRSITCWT
SINFRUP00000155284      LKELLFHPDWVVKESGILVLGAIAEGCMQGMIPYLPELIPHLVQCLSDKKALVRSITCWT
SINFRUP00000137496      LKGLLFHHDWVIKESGILVLGAIAEGCMQGMVPYLPELIPHLIQCLCDKKALVRSIACWT
SINFRUP00000156613      LKDLLFHPDWVVKESGILVLGAIAEGCMQGMVPYLPELIPHLIQCLCDKKALVRSIACWT
ENST00000222183         LKGLLFHPEWVVKESGILVLGAIAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWT
ENSMUST00000005288      LKGLLFHPEWVVKESGILVLGAIAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWT
CG7398-RA               LKETLFHQEWVIKESGVLALGAIAEGCMQGMIQHLPELIPYLISCLSDKKALVRSITCWT
                        **  *** :**:****:*.************: :******:*:.**.*********:***

ENST00000261412         LSRYAHWVVSQPPDTYLKPLMTELLKRILDSNKRVQEAACSAFATLEEEACTELVPYLAY
ENSMUST00000040075      LSRYAHWVVSQPPDTYLKPLMTELLKRILDSNKRVQEAACSAFATLEEEACTELVPYLAY
SINFRUP00000155284      LSRYAHWVVSQPPDTYLKPLMTELLKRILDSNKRVQEAACSAFATLEEEACTELVPYLAF
SINFRUP00000137496      LSRYAHWVVSQPPDAHLKPLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSF
SINFRUP00000156613      LSRYAHWVVSQPPDSYLKPLMTELLKRILDSNKRVQEAACSAIATLEEEACTELVPYLSF
ENST00000222183         LSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSY
ENSMUST00000005288      LSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSY
CG7398-RA               LSRYANWVVNQPHDQYLKPLMEELLKRILDSNKRVQEAACSAFATLEEEACTELVPYLEY
                        *****:***.** * :***** ********.***********:*************** :

ENST00000261412         ILDTLVFAFSKYQHKNLLILYDAIGTLADSVGHHLNKPEYIQMLMPPLIQKWNMLKDEDK
ENSMUST00000040075      ILDTLVFAFSKYQHKNLLILYDAIGTLADSVGHHLNKPEYIQMLMPPLIQKWNMLKDEDK
SINFRUP00000155284      ILDTLVFAFSKYQHKNLLILYDAIGTLADSVGHHLNKPEYIQMLMPPLIQKWNQLKDEDK
SINFRUP00000137496      ILDTLVFAFGKYQHKNLLILYDAIGTLADSVGHHLNQPEYIQKLMPPLIAKWNELKDEDK
SINFRUP00000156613      ILDTLVFAFGKYQHKNLLILYDAIGTLADSVGHHLNQLDYIQKLMPPLIAKWNELKDEDK
ENST00000222183         ILDTLVFAFGKYQHKNLLILYDAIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDK
ENSMUST00000005288      ILDTLVFAFGKYQHKNLLILYDAIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDK
CG7398-RA               ILKTLVFAFSKYQHKNLLILYDAVGTLADSVGHHLNKPQYIDILMPPLIDKWNLLKDDDK
                        **.******.*************:************: :**: ****** *** ***:**

ENST00000261412         DLFPLLEC-LSSVATALQSGFLPYCEPVYQRCVNLVQKTLAQAMLNNAQPDQYEAPDKDF
ENSMUST00000040075      DLFPLLEC-LSSVATALQSGFLPYCEPVYQRCVNLVQKTLAQAMLNNAQPEQYEAPDKDF
SINFRUP00000155284      DLFPLLEAMLSSVATALQSGFLPYCEPVYQRCVNLVQKTLAQAMLYQSQPDQYESPDKDF
SINFRUP00000137496      DLFPLLEC-LSSVATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYSQQPDQYEAPDKDF
SINFRUP00000156613      DLFPLLEC-LSSVATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYNQHPDQYEAPDKDF
ENST00000222183         DLFPLLEC-LSSVATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDF
ENSMUST00000005288      DLFPLLEC-LSSVATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDF
CG7398-RA               DLFPLLEC-LSSIATALQSGFLPYCDPVYRRCISLIEQTINQEMLCKQN-QTYDHPDKER
                        *******. ***:************:***:**:.*:::*: * *:   : : *: ***: 

ENST00000261412         MIVALDLLSGLAEGLGGNIEQLVARSNILTLMYQCMQDKMPEVRQSSFALLGDLTKACFQ
ENSMUST00000040075      MIVALDLLSGLAEGLGGNIEQLVARSNILTLMYQCMQDKMPEVRQSSFALLGDLTKACFQ
SINFRUP00000155284      MIVALDLLSGLAEGLGGTIEQLVACSNILTLMYQCMQDKMPEVRQSSFALLGDLTKACFQ
SINFRUP00000137496      MIVALDLLSGLAEGLGGHVDTLVARSNIMTLLFQCMQDTMPEVRQSSFALLGDLTKACFL
SINFRUP00000156613      MIVALDLLSGLAEGLGGHVEQLVARSNIMTLLFQCMQDTMPEVRQSSFALLGDLTKACFP
ENST00000222183         MIVALDLLSGLAEGLGGHVEQLVARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFI
ENSMUST00000005288      MIVALDLLSGLAEGLGGHVEQLVARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFI
CG7398-RA               MIVALDLLSGLAEGLDRHIETLVANSNIMHLLYQCMQDVLPEVRQSSFALLGDLTKACFP
                        ***************.  :: *** ***: *::***** :******************* 

ENST00000261412         HVKPCIADFMPILGTNLNPEFISVCNNATWAIGEISIQMGIEMQPYIPMVLHQLVEIINR
ENSMUST00000040075      HVKPCIADFMPILGTNLNPEFISVCNNATWAIGEISIQMGIEMQPYIPMVLHQLVEIINR
SINFRUP00000155284      HVKPCIADFMPVLGTNLNPELISVCNNATWAIGEISIQMGPEMQPYVAMVLHQLVEIINR
SINFRUP00000137496      HVKPCIAEFMPILGTNLNPEFISVCNNATWAIGEICMQMGVEMQPYIAMVLNQLVEIINR
SINFRUP00000156613      HVKPCISEFMPILGLNLNPEFISVCNNATWAIGEISMQMGAEMQPYVGLVLPHLVEIINR
ENST00000222183         HVKPCIAEFMPILGTNLNPEFISVCNNATWAIGEICMQMGAEMQPYVQMVLNNLVEIINR
ENSMUST00000005288      HVKPCIAEFMPILGTNLNPEFISVCNNATWAIGEICMQMGAEMQPYVQMVLNNLVEIINR
CG7398-RA               HVHPFMADFFPILGQNLNPDFISVCNNATWAIGEICMKLGEETKQYIRLVLSDLFIIINR
                        **:* :::*:*:** ****::**************.:::* * : *: :** .*. ****

ENST00000261412         PNTPKTLLEN-----------TAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEE
ENSMUST00000040075      PNTPKTLLEN-----------TAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEE
SINFRUP00000155284      PNTPKTLLEN-----------TAITIGRLGYVCPQEVAPMLQQFIRPWCSSLRNIRDNEE
SINFRUP00000137496      PNTPKTLLEN-----------TAITIGRLGYVCPQEVAGMLPQFIRPWCTSLRNIRDNEE
SINFRUP00000156613      PSTPKTLLENTVDTNSLSSLRAAITIGRLGYVCPQEVAPQLQQFIRPWCSSLRNIRDNEE
ENST00000222183         PNTPKTLLEN-----------TAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEE
ENSMUST00000005288      PNTPKTLLEN-----------TAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEE
CG7398-RA               PNTPKTLLEN-----------TAITIGRLGYVCPVEVAPYLPEFVRQWCTSLRHIRDNDE
                        *.********           :************ ***  * :*:* **:***:****:*

ENST00000261412         KDSAFRGICTMISVNPSGVIQDFIFFCDAVASWINPKDDLRDMFCKILHGFKNQVGDENW
ENSMUST00000040075      KDSAFRGICTMISVNPSGVIQDFIFFCDAVASWINPKDDLRDMFCKILHGFKNQVGDENW
SINFRUP00000155284      KDSAFRGICTMITVNPGGVVQDFIFFCDAVASWVNPKDDLRDMFYKILHGFKNQVGDDNW
SINFRUP00000137496      KDSAFRGICMMIGVNPGGVVQDFIFFCDAVASWVNPKDDLRDMFYKILHGFKEQVGEENW
SINFRUP00000156613      KDSAFRGICVMIGVNPAGVVQDFIFFCDAVASWVNPKDDLRDMFYKILHGFKDQVGEENW
ENST00000222183         KDSAFRGICMMIGVNPGGVVQDFIFFCDAVASWVSPKDDLRDMFYKILHGFKDQVGEDNW
ENSMUST00000005288      KDSAFRGICMMIGVNPGGVVQDFIFFCDAVASWVSPKDDLRDMFYKILHGFKDQVGEENW
CG7398-RA               KDSAFRGMCHMITVNPAGVVADFIFFCDAIASWVNPPEDLHQMIQKILHGFKTQVGEENW
                        *******:* ** ***.**: ********:***:.* :**::*: ******* ***::**

ENST00000261412         RRFSDQFPLPLKERLAAFYGV
ENSMUST00000040075      RRFSDQFPLPLKERLAAFYGV
SINFRUP00000155284      RRFADQFPVPLKERLA-FYGV
SINFRUP00000137496      QQFSEQFPPLLKERL------
SINFRUP00000156613      QQFSEQFPPLLKERLSACYGV
ENST00000222183         QQFSEQFPPLLKERLAAFYGV
ENSMUST00000005288      QQFSEQFPPLLKERLAAFYGV
CG7398-RA               RRFVEQFPPTLAERLTTMYNI
                        ::* :***  * ***