CLUSTAL W (1.82) multiple sequence alignment


ENST00000255145         --MNYVGQLAETVFGTVKELYRGLNPATLSGGIDVLVVKQVDGSFRCSPFHVRFGKLGVL
ENSMUST00000040872      --MNYVGQLAETVFGTVKELYRGLNPATLSGGIDVLVVRQRDGSFRCSPFHVRFGKLGVL
ENSMUST00000048538      --MNYVGQLAGQVFVTVKELYKGLNPATLSGCIDIIVIRQPNGSLQCSPFHVRFGKMGVL
ENST00000256720         --MNYVGQLAGQVFVTVKELYKGLNPATLSGCIDIIVIRQPNGNLQCSPFHVRFGKMGVL
SINFRUP00000130208      QTMNYVGQLAGQVFVQVKELYRGLNPATLSGCIDVIVVKQPDGSLQCSPFHVRFGKMGVL
CG8709-RA               ------MNSLARVFSNFRDFYNDINAATLTGAIDVIVVEQRDGEFQCSPFHVRFGKLGVL
                          :  : :    **  .:::*..:*.***:* **::*:.* :*.::**********:***

ENST00000255145         RSREKVVDIELNGEPVDLHMKLGDSGEAFFVQELESDD-EHVPPGLCTSPIPWGGLSGFP
ENSMUST00000040872      RSREKVVDIEINGEPVDLHMKLGDSGEAFFVQELDSDE-EDVPPRLCTSPIPWGGLSGFP
ENSMUST00000048538      RSREKVVDIEINGESVDLHMKLGDNGEAFFVQETDNDQ-EIIPMYLATSPILSEGAARME
ENST00000256720         RSREKVVDIEINGESVDLHMKLGDNGEAFFVQETDNDQ-EVIPMHLATSPILSEGASRME
SINFRUP00000130208      RSREKVVDMEINGEPVDLHMKLGDNGEAFFVQETENDQ-EVVPSYLATSPILSDGVILKT
CG8709-RA               RSREKVVDIEINGVPVDIQMKLGDSGEAFFVEECLEDEDEELPANLATSPIPNSFLASRD
                        ********:*:** .**::*****.******:*  .*: * :*  *.****         

ENST00000255145         S--------------DSQLGTASEPEGLVMAGTASTGRRKRR------------------
ENSMUST00000040872      S--------------DSQIGTASEPEGLVIT-----GRRKRR------------------
ENSMUST00000048538      SQLKRNSVDRIRCLDPTTAAQGLPPSDTPSTGSLGKKRRKRR------------------
ENST00000256720         CQLKRGSVDRMRGLDPSTPAQVIAPSETPSSSSVVKKRRKRR------------------
SINFRUP00000130208      SSLIG------RKNSVGQTIQTLGSTGSTGEAGGAKKRRKRR------------------
CG8709-RA               KANDTMEDISGVVTDKNASEELLLPLPLPRRNSIDFSKEEPKEAVVEGSKFENQVSDYTQ
                                                .            :.: :                  

ENST00000255145         ---------------------------------------RRRKPKQKEDAVATDSSPEE-
ENSMUST00000040872      ---------------------------------------RRRKPRRREED-AVDSSSEE-
ENSMUST00000048538      ---------------------------------------RKAQLDNLKRDDNVNTSEDED
ENST00000256720         ---------------------------------------RKSQLDSLKRDDNMNTSEDED
SINFRUP00000130208      ---------------------------------------RKARADSLWREESGEYSEDDD
CG8709-RA               RRHTDNTLERRNLSEKLKEFTTQKIRQEWAEHEELFQGEKKPADSDSLDNQSKASNEAET
                                                               ::              .  : 

ENST00000255145         ---LEAGAESELSLPEKLRPEPPGSVQLEEKSSLQ---------PKDIYPYSDGEWPPQA
ENSMUST00000040872      ---LEAGAESELTLLEKPTPESP-SAQEAEEPSSQ---------PKDIHPYSDGECTPQA
ENSMUST00000048538      MFPIEMSSDEDTAPMDGSRTLPNDVPPFQDDIPKENFPSISTYPQSASYPSSDREWSPSP
ENST00000256720         MFPIEMSSDEAMELLESSRTLPNDIPPFQDDIPEENLSLAVIYPQSASYPNSDREWSPTP
SINFRUP00000130208      MFTIDISSDEGTE-MESSRGTSRDI--LRDEAASG------SFQQSRLHTRSDGEWSPLQ
CG8709-RA               EKAIPAVIEDTEKEKDQIKPDVNLTTVTTSEATKEVSKSKTKKRRKKSQMKKNAQRKNSS
                           :    :.     :             .. .            .     .: :     

ENST00000255145         S---------------------------------LSAGELTSPKSDSELEV-----RTPE
ENSMUST00000040872      N---------------------------------LSSGDLMSPKSDSELEL-----RSLE
ENSMUST00000048538      SSLVDCQRTPPHLAEGVLSSSCPLQSCHFHASESPSGSRPSTPKSDSELVS-----KSAD
ENST00000256720         S---------------------------------PSGSRPSTPKSDSELVS-----KSTE
SINFRUP00000130208      S---------------------------------PGNSRSTSPKSDSELMS-----KSSE
CG8709-RA               SSSLGSAGGGDLPSAETPSLGVSNIDEGDAPISSATNNNNTSSSNDEQLSAPLVTARTGD
                        .                                    .   :...*.:*       :: :

ENST00000255145         PSPLRAESHMQWAWGRLPKVS---------------------------------------
ENSMUST00000040872      PSPLRAESHMQWVWGRLPKVAKAERPEFSLILESMAEAICALPEEPSPSSSPSEAGVDTL
ENSMUST00000048538      RLTPKNNLEMLWLWGELPQAAKSSSP--------------HKMKESSPLGSRKTPDKMNF
ENST00000256720         RTGQKN-PEMLWLWGELPQAAKSSSP--------------HKMKESSPLSSRKICDKSHF
SINFRUP00000130208      --AESQNPTMHWAWGELPQAATVSKE--------------YTVDTSARQKQTCFLQSQRF
CG8709-RA               DSPLSEIPHTPTSNPRLDLDIHFFSD----------------TEITTPVGGGGAGSGRAA
                                       .*                                           

ENST00000255145         ------------------------------------------------------------
ENSMUST00000040872      SPPVLHPGVRADTFHPAVEAHCEETAVDSPLAAPESKETKTQNSRGAGHPPATKSWSWTT
ENSMUST00000048538      QAIHSESSDTFSDQSPTMARGLLIHQSKAQTEMQFVNEEDLESLGAAAPPSPVAEELKAP
ENST00000256720         QAIHSESSDTFSDQSPTLVGGALLDQNKPQTEMQFVNEEDLETLGAAAPLLPMIEELKPP
SINFRUP00000130208      SFLLFQPSFLKVRSEPPPVCPESIPVSES-THFRVITPEMPSERREACSEIPELRLTGDM
CG8709-RA               GGRPSTPIQSDSELETTMRDNRHVVTEESTASWKWGELPTPEQAKNEAMSAAQVQQSEHQ
                                                                                    

ENST00000255145         -----------------SPKRSQHLGPSDIYLDDLPSLDSENAALYFPQS-DSGLGARRW
ENSMUST00000040872      PESHTPSGHPQVSRGKGSLKRNQHLGPSDIYLDDLPSLDSENVALYFPKS-EYGMGARRW
ENSMUST00000048538      YPNTAQSSSKTDSPSRKKDKRSRHLGADGVYLDDLTDMDPEVAALYFPKNGDPGGLPKQA
ENST00000256720         SASVVQTANKTDSPSRKRDKRSRHLGADGVYLDDLTDMDPEVAALYFPKNGDPSGLAKHA
SINFRUP00000130208      EETVTLPPGKTDSPTKRKDKRSRHLGSDGIYLDDITELKPEVAALYFPKS-DAGAAVRSL
CG8709-RA               SMLSNMFSFMKRANRLRKEKGVGEVGDIYLSDLDAGSMDPEMAALYFPSPLSKAASPPEE
                                           *   .:*   :   *  .:..* .*****.  . .      

ENST00000255145         SEPSSQKSLRDP---------NPEHEPEPTLDT-------VDTIALSLCGGLADSRDISL
ENSMUST00000040872      SEPSNQKLLESP---------NPEHIAECTLDS-------VDKIELSLCGGLADNRDISL
ENSMUST00000048538      SDNGARSANQSPQSVGGSGIDSGVESTSDSLRD-------LPSIAISLCGGLSDHREITK
ENST00000256720         SDNGARSANQSPQSVGSSGVDSGVESTSDGLRD-------LPSIAISLCGGLSDHREITK
SINFRUP00000130208      SDPGLHGTSLSPQTVS-SGGDSGVDSYCDHMAD-------LPSITISLCGGLADNREITK
CG8709-RA               DGESGNGTSLPHSPSSLEEGQKSIDSDFDETKQQRDNNRYLDFVAMSMCGMSEQGAPPSD
                        .  . .               .  .               :  : :*:**   :    : 

ENST00000255145         EKFNQHSVSYQDLTKNPGLLDDPNLVVKINGKHYNWAVAAPMILSLQAFQKNLPKVMVR-
ENSMUST00000040872      EKFTQHMVSYEDLTKNPGLLDDPNLVVKINEKHYNWAVAAPMILSLQAFQKNLPESTVDK
ENSMUST00000048538      DAFLEQAVSYQQFADNPAIIDDPNLVVKVGNKYYNWTTAAPLLLAMQAFQKPLPKATVES
ENST00000256720         DAFLEQAVSYQQFVDNPAIIDDPNLVVKIGSKYYNWTTAAPLLLAMQAFQKPLPKATVES
SINFRUP00000130208      G-----------FIAS-------HLVFIFR--YYNWSTAAPLMLAMQAFQKPLPKATVEK
CG8709-RA               EEFDRHLVNYPDVCKSPSIFSSPNLVVRLNGKYYTWMAACPIVMTMITFQKPLTHDAIEQ
                          :    :    .  .  ::   :**. .   :*.* .*.*::::: :*** *..  :  

ENST00000255145         -EHHGQA-------------------GEGEDAPEGWA--MVVFLATQGLPGR-------G
ENSMUST00000040872      LEKEKMP-------------------RKGGRWWFSWR--RRDFPAEEHSSQREKAATRKQ
ENSMUST00000048538      IMRDKMP-------------------KKGGRWWFSWRG-RNATIKEESKPEQCLTGKGHN
ENST00000256720         IMRDKMP-------------------KKGGRWWFSWRG-RNTTIKEESKPEQCLAGKAHS
SINFRUP00000130208      IMKEKMP-------------------KKGGRWWFSWRG-RNSGNKSDSASDGGACGSAEQ
CG8709-RA               LMSQTVDGKCLPGDEKQEAVAQADNGGQTKRYWWSWRRSQDAAPNHLNNTHGMPLGKDEK
                           .                       :      .*             .          

ENST00000255145         GGEK------TEVLSS----DDDAPDSPVILEIPSLPPSTPPSTP-------------TY
ENSMUST00000040872      QGEK------TEVLSS----DDDVPDSPVILEVPPLPSSTPGYVP-------------TY
ENSMUST00000048538      TGEQPAQLGLATRIKH----ESSSSDEEHAAAKPSGSSHLSLLSN------------VSY
ENST00000256720         TGEQPPQLSLATRVKH----ESSSSDEERAAAKPSNAGHLPLLPN------------VSY
SINFRUP00000130208      AG------KMTNRHKE----ESSSSDEDLRAAKQSSSAIQTDLVLGSGG--------VSY
CG8709-RA               DGDQAAVATQTSRPTSPDITDPTLSKSDSLVNAENTSALVDNLEELTMASNKSDEPKERY
                         *        :   .     :   ...         .                      *

ENST00000255145         KKSLRLSSDQIRRLNLQEGANDVVFSVTTQYQGTCRCKATIYLWKWDDKVVISDIDGTIT
ENSMUST00000040872      KKSLRLSSDQIRCLNLNEGANDVVFSVTTQYQGTCRCKATIYLWNWDDKVVISDIDGTIT
ENSMUST00000048538      KKTLRLTSEQLKSLKLKNGPNDVVFSVTTQYQGTCRCEGTIYLWNWDDKVIISDIDGTIT
ENST00000256720         KKTLRLTSEQLKSLKLKNGPNDVVFSVTTQYQGTCRCEGTIYLWNWDDKVIISDIDGTIT
SINFRUP00000130208      KKTLRLTSEQLMSLQLQDGPNDVIFSVTTQYQGTCRCQGTIYLWNWDDKIIISDIDGTIT
CG8709-RA               KKSLRLSSAAIKKLNLKEGMNEIEFSVTTAYQGTTRCKCYLFRWKHNDKVVISDIDGTIT
                        **:***:*  :  *:*::* *:: ***** **** **:  :: *: :**::*********

ENST00000255145         KSDALGHILPQLGKDWTHQGITSLYHKIQLNGYKFLYCSARAIGMADLTKGYLQWVSEGG
ENSMUST00000040872      KSDALGHILPQLGKDWTHQGITSLYHKIHLNGYKFLYCSARAIGMADLTKGYLQWVSEHG
ENSMUST00000048538      RSDTLGHILPTLGKDWTHQGIAKLYHKVSQNGYKFLYCSARAIGMADMTRGYLHWVNERG
ENST00000256720         RSDTLGHILPTLGKDWTHQGIAKLYHKVSQNGYKFLYCSARAIGMADMTRGYLHWVNERG
SINFRUP00000130208      RSDTLGHILPTLGKDWTHQGIAQLYHKVSQNGYKFLYCSARAIGMADMTRGYLHWVNERG
CG8709-RA               KSDVLGHILPMVGKDWAQLGVAQLFSKIEQNGYKLLYLSARAIGQSRVTREYLRSIRQGN
                        :**.****** :****:: *::.*: *:  ****:** ****** : :*: **: : : .

ENST00000255145         CSLPKGPILLSPSSLFSALHREVIEKKPEVFKVACLSDIQQLFLPHGQPFYAAFGNRPND
ENSMUST00000040872      CGLPKGPILLSPSSLFSALHREVIEKKPEVFKVACLSDIQQLFLPQRQPFHAAFGNRPND
ENSMUST00000048538      TVLPQGPLLLSPSSLFSALHREVIEKKPEKFKVQCLTDIKNLFFPNTEPFYAAFGNRPAD
ENST00000256720         TVLPQGPLLLSPSSLFSALHREVIEKKPEKFKVQCLTDIKNLFFPNTEPFYAAFGNRPAD
SINFRUP00000130208      TMLPMGPVLLSPSSLFSALHREVIERKPEIFKVECLNDIRTLFSPNQQPFYAAFGNRPTD
CG8709-RA               VMLPDGPLLLNPTSLISAFHREVIEKKPEQFKIACLSDIRDLF-PDKEPFYAGYGNRIND
                          ** **:**.*:**:**:******:*** **: **.**: ** *. :**:*.:***  *

ENST00000255145         VFAYRQVGLPESRIFTVNPRGELIQELIKNHKST-YERLGEVVELLFPPVARGP------
ENSMUST00000040872      VFAYRQVGLPESRIFTVNPRGELIQELIKSHKST-YQRLGEVVELLFPPVVRGP------
ENSMUST00000048538      VYSYKQVGVSLNRIFTVNPKGELVQEHAKTNISS-YVRLCEVVDHVFPLLKRSH------
ENST00000256720         VYSYKQVGVSLNRIFTVNPKGELVQEHAKTNISS-YVRLCEVVDHVFPLLKRSH------
SINFRUP00000130208      VYSYKEAGVPLNRIFTVNPKGELVQEHAKTNVSS-YVRLSEVVDHVFPLKTRTS------
CG8709-RA               VWAYRAVGIPIMRIFTINTKGELKHELTQTFQSSGYINQSLEVDEYFPLLTNQDEFDYRT
                        *::*: .*:.  ****:*.:*** :*  :.  *: * .    *:  **   .        

ENST00000255145         -------------------------STDLAN-PEYSNFCYWREPLPAVDLDTLD------
ENSMUST00000040872      -------------------------STDLAS-PEYSNLSYWRKPLPYVDFEALA------
ENSMUST00000048538      -------------------------SCDFPCSDTFSNFTFWREPLPPFENQDMHSASA--
ENST00000256720         -------------------------SSDFPCSDTFSNFTFWREPLPPFENQDIHSASA--
SINFRUP00000130208      -------------------------SSDFPCSDTFSHFTYWRQQLPLVEDR---------
CG8709-RA               DIFDDEESEEELQFSDDYDVDVEHGSSEESSGDEDDDEALYNDDFANDDNGIQAVVASGD
                                                 * : .     ..   :.. :.  :           

ENST00000255145         --------------------------------
ENSMUST00000040872      --------------------------------
ENSMUST00000048538      --------------------------------
ENST00000256720         --------------------------------
SINFRUP00000130208      --------------------------------
CG8709-RA               ERTADVGLIMRVRRVSTKNEVIMASPPKWINS