CLUSTAL W (1.82) multiple sequence alignment


SINFRUP00000136522      ------------------------------------------------------------
ENST00000311785         -MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKS
SINFRUP00000142454      -MRLKEIQRTAHQAWSPAGHHPMYLALGTAAQQLDASFNTTAALEIFEMDFSQPSLDMQL
ENST00000189226         -MKLKELERPAVQAWSPASQYPLYLATGTSAQQLDSSFSTNGTLEIFEVDFRDPSLDLKH
ci0100143441            MVKIKQVNVGANYAWSPAENHPVYIAAGTAAQQLDATFSSNAKLELYAVDMTDDNYNIKC
CG8266-RA               -MKIKELQKTVNIAWSPAQQQQILLAAGTAAQQFDS--NANSTLELYSPNFSDATYDLEL
                                                                                    

SINFRUP00000136522      ---------YHKLVWGPHGMDDSGHPSGVLIAGSENGDVILYDPAKIMAGESDVIIAESD
ENST00000311785         CATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQND
SINFRUP00000142454      KGSLRTPNRLHSIVWVNFGMGADG-SGGRLIGGSENGILTVYNPDIIMSSGADAVVGQSD
ENST00000189226         RGVLSALSRFHKLVWGSFGSGLLE-SSGVIVGGGDNGMLILYNVTHILSSGKEPVIAQKQ
ci0100143441            AGSIETENRFQKVVWG-SGYAENPTTSGLIVCGTDKGGIEIYNPEKILENEVDCILSNS-
CG8266-RA               RASVSSQYKFQKLIWSPVGPHPSG----LIVGGCEAGQINIYSADKLLAGKEEPLLKRQD
                                  :.::*              :: * : * : :*.   :: .  : :: .. 

SINFRUP00000136522      RHTGPVRALDINPFQTNLVASGGNESEIYIWDLNNFGSPMTPGPKTQ-------------
ENST00000311785         KHTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPED-ISCIAWNR
SINFRUP00000142454      KHTGPIRALDFNPFQSNLLASGANDSEIYIWDLNNFSSPMTPGAKT-QPVEDISVVSWNR
ENST00000189226         KHTGAVRALDLNPFQGNLLASGASDSEIFIWDLNNLNVPMTLGSKSQQPPEDIKALSWNR
ci0100143441            KHTGPVRSLDFNNFQKNLFASGANDSEIYIWDLKNPSNPMTPGTKTQPTSA-VGALAWNK
CG8266-RA               KHTGAVSGLDFNPFQNNLLASCASESEILIWDLNNPETSMSPGTKTQPLED-VKNVAWNR
                        :***.: .**.* ** **.** ..:*** ****:*   .*: *.*:              

SINFRUP00000136522      --------------------------------------MHCSGLAWNPEVATQLILASED
ENST00000311785         QVQHILASASPSGR---ATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASED
SINFRUP00000142454      QVQHILASANPSGK---AVVWDLRKNEPIIKISDHSNRMHCSGMLWHPDVATQLVLASED
ENST00000189226         QAQHILSSAHPSGK---AVVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDIATQLVLCSED
ci0100143441            QVQHILASTSSLTSGPCCVVWDLRKNEPIIKVQDPSGRMQCSDVSWHPDVATQLVLSSED
CG8266-RA               QVQHILASVFSTR----CVIWDLRKSQQIIKLSDSQSRVRWHAIEWHPEAATQVWLASED
                                                              ::   : *:*: ***: *.***

SINFRUP00000136522      DRMPVIQMWDLRFATSPLKILENHTRGVLSIAWSMADPELLLSCGKDSRILCWNPNTA--
ENST00000311785         DRLPVIQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTG--
SINFRUP00000142454      DRLPVIQMWDLRFATSPLKVLENHTRGILSISWSQADSELLLSSAKDNRILCWNPNTG--
ENST00000189226         DRLPVIQLWDLRFASSPLKVLESHSRGILSVSWSQADAELLLTSAKDSQILCRNLGSS--
ci0100143441            DHLPVVQLWDLRFATSPMKVLEKHSKGVLSVSWCKQDSDLLLTCGKDNHIYCWNPNGSPP
CG8266-RA               DQAPVVQLWDLRYATAPAKTYQIHERGVLGMSWCLQDNDLMVSCGKDNRIYCWNPNTKIP
                        *: **:*:****:*::* :  : * :*:*.::*.  * :*:::..** :* * * .    

SINFRUP00000136522      --EVLYELPTSSQWCFDIQWCPRNPAVLSAAGFDGHIDIFSIMGGS---SQAQSQRHADQ
ENST00000311785         --EVLYELPTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGS---TDGLRQKQVDK
SINFRUP00000142454      --EVVYELATTNQWCFDVQWCPRNPALLSTASFDGKITVYSVMGGS---LKAQQQSTADQ
ENST00000189226         --EVVYKLPTQSSWCFDVQWCPRDPSVFSAASFNGWISLYSVMGRS---WEVQHMRQADK
ci0100143441            --EILCELETGAQWCFDVQWCPRNPNILSTGSFDGCISIHSIMGGSPVQSNDQNQAQRNK
CG8266-RA               EGEILSEVATTASWYSDVQFCPRNPALIASASLEGAVSIYSLHGGT-----HHLVQTANK
                          *:: :: *  .*  *:*:***:* ::::..::* : :.*: * :            ::

SINFRUP00000136522      ISTSFGNMDPFGTGQTLPPLQLPQAAAPSATITQMKKPPKWIRRPVAASFGFGGKLVSLE
ENST00000311785         LSSSFGNLDPFGTGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFE
SINFRUP00000142454      ISSSFDTMDPFGTGQVLPPLQVPHPTVQDTIVPPLKKPPKWMRRPVGASFGFGGKLISFE
ENST00000189226         ISSSFS------KGQPLPPLQVPEQVAQAPLIPPLKKPPKWIRRPTGVSFAFGGKLVTFG
ci0100143441            IADAFG-------SDAFAGDAPQQQHTQPKKTIPLKKPPKWMRRPCAASFSFGGKLVSFE
CG8266-RA               IADSFP-------GMDQFAQEPIPQQATQVVYHDLAHAPKWMKRPCGVAFGFGGKLVSFN
                        :: :*  :  :  .            .       : :.***::** ..:*.*****::: 

SINFRUP00000136522      NPKPNPQQ--PQQHGPHVVHISQVVTETDFLKRSDQLQATLNTG-TFVDFCQGKIGAAVN
ENST00000311785         NVRMPSHQGAEQQQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQ-GFINYCQKKIDASQT
SINFRUP00000142454      NPKVPPMQ--SPQPIPRQVFLSQVTTETEFLQRSKELQAALQSG-SFNSYCQTKIQNARS
ENST00000189226         LPSTPAHL--VPQPCPRLVFISQVTTESEFLMRSAELQEALGSG-NLLNYCQNKSQQALL
ci0100143441            NNQTTENQ--HQTSSHRTVKISQVVTEVELLERSADLRKALTDDTQCTAYCHRKLEKAQS
CG8266-RA               G-------------TSKTVKVQQLTTESALVDRANALERSLVDA-NYSDYCRQRADETPD
                                        : * :.*:.**  :: *:  *. ::        :*: :   :  

SINFRUP00000136522      EFEKTLWSFLKANFESDVRRKYLELLGYNKEELALKSDGEATEVEEPEVA----ADFQDD
ENST00000311785         EFEKNVWSFLKVNFEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVA----LKDSDQ
SINFRUP00000142454      DAEQDIWKFLLVNFEDEARVKFLKLLGFSKDDIEKKVFCVLCS-----------------
ENST00000189226         QSEKMLWQFLKVTLEQDSRMKFLKLLGYSKDELQKKVATWLKSDVGLGES----PQPKGN
ci0100143441            EFEENFWSFLKVNFEPEPRKEFLQLLGYNPVELTAKFSKVLGTTTNGISSGIDSLSISAK
CG8266-RA               QHGRYIWYFIKANFELNPKEEMLNLLGYNKDDIDSKFNKFIKETDGNSHS---------D
                        :  . .* *: ..:* : : : *:***:   ::  *                        

SINFRUP00000136522      ASDEPKEME--ELEEEEIP----LEEVSFIFFLTMFGSVIQFRLGH-NVDGLITQALLTG
ENST00000311785         VAQSDGEES--PAAEEQLLGEHIKEEKEESEFLPSSGGTFNISVSG-DIDGLITQALLTG
SINFRUP00000142454      ------------------------ISVCFPHIYHIKSLVFLSPWDQ-DTDGLISQALLVG
ENST00000189226         DLNSDRQQAFCSQASKHTTKEASASSAFFDELVPQNMTPWEIPITK-DIDGLLSQALLLG
ci0100143441            SESGDDNVSNGASSSNGLDAFEQIAVAQETKKQEEEIKPMVIPVADGDIDSLISQALLIG
CG8266-RA               VDTLTTRISTLTHTQDNKFDGNAIDSQNHNDFATPPRPQFKVPSGD-HSDSLIAEAILTG
                                                                       . *.*:::*:* *

SINFRUP00000136522      NFEGAVELCLHDNRMADSIILAIAGGPELLEKTQKKYFTKTHSKITKVITCILFYGINAS
ENST00000311785         NFESAVDLCLHDNRMADAIILAIAGGQELLARTQKKYFAKSQSKIT--------------
SINFRUP00000142454      NFEGAVDLCLNDGRYPEAILLSISGGEELLKKTQQKYLLKQKNSIS--------------
ENST00000189226         ELGPAVELCLKEERFADAIILAQAGGTDLLKQTQERYLAKKKTKIS--------------
ci0100143441            DYEAAVDLCLHSNRMADAIVVAMAGGSKLLEKTQKRYFDASESKIS--------------
CG8266-RA               NVDAAVELCLEAQRIPEALIIASTAGIETLNRTQTRYLLQQKNELS--------------
                        :   **:***.  * .:::::: :.* . * :** :*:   ...:: ::  :::  :   

SINFRUP00000136522      LLILFFFFRLISAVVMKDWHDILQTCELQNWKEALAAVMTYARPEEFSSLCG----RLKV
ENST00000311785         --------RLITAVVMKNWKEIVESCDLKNWREALAAVLTYAKPDEFSALCDLLGTRLEN
SINFRUP00000142454      --------MLISSVVTQNWRDIVQSCDLDNWKEALAALLTYAHPEDFACLCDILGGRLEN
ENST00000189226         --------SLLACVVQKNWKDVVCTCSLKNWREALALLLTYSGTEKFPELCDMLGTRMEQ
ci0100143441            --------RLLSAVVTKNWADVVKSCDLENWKEALASLLTYASPQDLISLCDELGERLEA
CG8266-RA               --------HVISALVSRDWLDFVNRCTVDSWKEALVAALKHSE-RKVVDICERLGDRLLS
                        :::::::: :::.:* ::* :.:  * :..*:***.  :.::   ..  :*     *:  

SINFRUP00000136522      IGR--------------CSHYVLKSTLIHERVWR--------------LCDLVEKVVVLQ
ENST00000311785         EGDS--LLQTQACLCYICAGNVEKLVACWTKAQDG--------SHPLSLQDLIEKVVILR
SINFRUP00000142454      EKTE--KCCLQACLCYICSGNIERLVECWTSHRDS--------SSPLGLEDLVEKVMMLR
ENST00000189226         EGSR--ALTSEARLCYVCSGSVERLVECWAKCHQA--------LSPMALQDLMEKVMVLN
ci0100143441            NPEL--K--SHACLCYICSGNIERLVRCWSSVNSQD-------NNGNDIQDLIEKMMVLH
CG8266-RA               ECASSAEFTRNAMLCYICAGSIDKLVTAWYQLKRLEQQNPGYKPNTTELQDLAEMVMLMC
                                         *:  : : .                      : ** * :::: 

SINFRUP00000136522      QAVEV-TQKSGPAAIGILLAEKMSQYANLLASQGSLSTAIKYLPDN------TNQ-----
ENST00000311785         KAVQL-TQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDN------TNQPNIMQ
SINFRUP00000142454      KSIER-LRNCEVAVQSPILAEKLTCYAGILAAEGSLTTAMTYLPEN------SDQ-----
ENST00000189226         RSLEQ-LRGPHGVSPGPATTYRVTQYANLLAAQGSLATAMSFLPRD------CAQPPVQQ
ci0100143441            RVAEQRSQGGSAASMGEASSEKLSEYAHMLASQGQLGAAMEMLPAH------SDKISIQI
CG8266-RA               KSLEQ---QGISVDLAGRFAGFLTEYGGLLASQGALTAALQYITTLGGGAAASESDVLQS
                        :  :           .   :  :: *. :**::* : :*:  :.          .     

SINFRUP00000136522      ------------------------------------------------------------
ENST00000311785         LRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPPP
SINFRUP00000142454      ------------------------------------------------------------
ENST00000189226         LRDRLFHAQGSAVLGQQSPPFPFPRIVVGATLHSKETSSYRLGSQPSHQVP--TPSPRPR
ci0100143441            LRDRLYHSQGDTVVGYQPPVFPFSR------------DGSRVGHRPEAQVQPRRQMGAKG
CG8266-RA               LRDRINNAVNLDYTQPQAAVAAAPHGYQPTRGRGSFSQPQPSAPMPYGQPPNQYAQPSWP
                                                                                    

SINFRUP00000136522      ------------------------------------------------------------
ENST00000311785         GFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGG-----SAMYRPQ
SINFRUP00000142454      ------------------------------------------------------------
ENST00000189226         VFTPQSSPAMPLAPSHPSPYQGPRTQNISDYRAPGPQAIQPLPLSPGVRPASSQPQLLGG
ci0100143441            MYQQQQHLQHAHQPTSTSRPLQPQISIPNYQPPSVPSPHRPQVNNPYARPMQQPSYSGPQ
CG8266-RA               AQVPPLQTSYPGAQQPQAPPQIFNPQPVKPEPLAQPPRPLSNASSSGGPPPAGGASSSGG
                                                                                    

SINFRUP00000136522      ------------------------------------------------------------
ENST00000311785         QPVAPPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHG
SINFRUP00000142454      ------------------------------------------------------------
ENST00000189226         QRVQVPNPVGFPGTWPLPGSPLPMACPGIMRPGSTSLPETPRLFPLLPLRPLGPGRMVSH
ci0100143441            APSNIFTPPSVAPTSQVTGMMPVQAPSAPYQPYMAPTPQTMSQSMGNPPQP--PSNMYAP
CG8266-RA               SGLSGRSKYVLDPSVAAPTSSYGMPYNPVPAPVPSAVPFGGGGVPGPAPQPASVPTYNSN
                                                                                    

SINFRUP00000136522      ------------------------------------------------------------
ENST00000311785         GPGAPPSSSAYALPPGTTGTL-----------------PAASELP--ASQRTGPQNGWND
SINFRUP00000142454      ------------------------------------------------------------
ENST00000189226         TPAPPASFPVPYLPGDPGAPC-----------------SSVLPTTGILTPHPGPQDSWKE
ci0100143441            DMEKKHNSGGWNDPPALDPNR-----------------VPKKKKPTTVQSPPVANFLVPS
CG8266-RA               AFNTNPIAAAQPYNPSPLMPAQQNQFVPGVNPIETMPPPAVPPVIQNVQRNPTPPPGWND
                                                                                    

SINFRUP00000136522      ------------------------------------------------------------
ENST00000311785         PPALNRVPKKKKMPENFMPPVPITSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHL
SINFRUP00000142454      ------------------------------------------------------------
ENST00000189226         APAPRGNLQRNKLPETFMPPAPITAPVMSLTPELQGILPSQPPVS---------------
ci0100143441            QPAIPHDVYKQPTPKPIDPAQLNLMTPAAPVHNPMGNMMRPGVSPMMGG-----------
CG8266-RA               PPALKSS--RAPKPKPVVEPSAAIFHPLFPVDPNQNQNGYVDPSQYQHAAPLGGVPNTYY
                                                                                    

SINFRUP00000136522      ------------------------------------------------------------
ENST00000311785         PGGQPFHGVQQPLGQTGMPPSFSKPNIEGAPGAPIG----------NTFQHVQSLPTKKI
SINFRUP00000142454      ------------------------------------------------------------
ENST00000189226         -------------------------SVSHAPPGVPG----------ELSLQLQHLPPEKM
ci0100143441            ----------------------VQPSNNMMQNVPSS----------APAPSVPTGALKDT
CG8266-RA               NPAAFNNNPQQQQQHQQSYLQPQQPAPGIQQPNWQGQQQTIGYTEQPAPIQQQRQPAPPK
                                                                                    

SINFRUP00000136522      ------------------------------------------------------------
ENST00000311785         TKKPIPDEHLILKTTFEDLIQRCLSSATDPQTKRKLDDASKRLEFLYDKLREQTLSPTIT
SINFRUP00000142454      ------------------------------------------------------------
ENST00000189226         ERKELPPEHQSLKSSFEALLQRCSLSATDLKTKRKLEEAAQRLEYLYEKLCEGTLSPHVV
ci0100143441            PKSPIPAEHQILQVQFDQLIKKALNQNPNQQIKRKLDDCSRRLEFLYDKLRANSLSPNII
CG8266-RA               EKPPLPEEYIYLQTVLEELKNRCLGATNDPRTKRKFVDVVKRLENLYDCLRDGKLTPTTV
                                                                                    

SINFRUP00000136522      --------------------------------------------------------
ENST00000311785         SGLHNIARSIETRNYSEGLTMHTHIVSTSNFSETSAFMPVLKVVLTQANKLGV---
SINFRUP00000142454      --------------------------------------------------------
ENST00000189226         AGLHEVARCVDAGSFEQGLAVHAQVAGCSSFSEVSSFMPILKAVLIIAHKLLV---
ci0100143441            GGLHQVAQSMESRDYANGLRHHTRIVTQSNFSEISAFMPGLKSLLQIAGQLRI---
CG8266-RA               QYLNQIVQYIQISDYANAMEIHTQIAFGTDFAQCAGFMQGLKVLLQSASELQLVLR