CLUSTAL W (1.82) multiple sequence alignment


ENST00000257142         MEETQPPPQPKLPLCDSLMIWLQTFNTASPCQDVKQLTSGVAMAQVLHQIDAAWFNESWL
ENSMUST00000030306      MEDPQPLPQSELPLCDSLIIWLQTFKTASPCQDVKQLTNGVTMAQVLHQIDVAWFSESWL
SINFRUP00000138525      ----------------TFFLQLQTFSLSAPCSSAEELTTGAAISQALHQIDPAWFSESWL
ENST00000307602         --MFSVESLERAELCESLLTWIQTFNVDAPCQTVEDLTNGVVMAQVLQKIDPAYFDENWL
ENSMUST00000037154      --MFNVESVERVELCESLLTWIQTFNVDAPCQTAEDLTNGVVMSQVLQKIDPVYFDDNWL
SINFRUP00000138959      ------------------------------------------------------------
ENST00000264827         ------MSVDKAELCGSLLTWLQTFHVPSPCASPQDLSSGLAVAYVLNQIDPSWFNEAWL
ENSMUST00000005275      ------MSVDKAELCGSLLTWLQTFQVSPPCASPQDLSSGLAIAHVLNQIDPSWFNNEWL
CG10653-RA              ------MSAPKNEMYYSLLEWFKTLNLNAPHADAESLADGVALAQALNQFAPESFTDAWL
                                         ::  :  :           :     :   :  :    :    :

ENST00000257142         SRIKE-DVGDNWRIKASNVKKVLQGIMSYYHEFLGQQISEALIPDLNQITECSDPVELGR
ENSMUST00000030306      SRIKD-DVGDNWRIKASNLKKVLHGITSYYHEFLGQQISEELIPDLNQITECADPVELGR
SINFRUP00000138525      SRIKT-DVEENWRLKMNNLKKILQQVLDYYNEVLVQDISHLPLPDVALVAEHAEPTELGR
ENST00000307602         NRIKT-EVGDNWRLKISNLKKILKGILDYNHEILGQQINDFTLPDVNLIGEHSDAAELGR
ENSMUST00000037154      NRIKT-EVGDNWRLKECDYNLLVS------IQILGQQINDFTLPDVNLIGEHSDAAELGR
SINFRUP00000138959      ------------------------------------------------------------
ENST00000264827         QGISE-DPGPNWKLKVSNLKMVLRSLVEYSQDVLAHPVSEEHLPDVSLIGEFSDPAELGK
ENSMUST00000005275      QGISE-DSSPSWRLKVRKLEKILQSLVEYSKNVLGHPVSDQHLPDVSLIGEFSNPAELGK
CG10653-RA              SKIKASAVGSNWRLRMSNLKKVTQSVYDYYSDVLNYSLSDFSKPDLQRIAEKCDLGELER
                          :          :       :   :      .:   :       :  :        :  

ENST00000257142         LLQLILGCAINCEKKQEHIQNIMTLEESVQHVVMTAIQELMSKEILSSPPNDAVGELEQQ
ENSMUST00000030306      LLQLILGCAVNCEKKQEHIKNIMTLEESVQHVVMTAIQELMSKEIVISPASDTVGELEQQ
SINFRUP00000138525      LLQLVLGCAVNCERKQEYIQIIMTLEEAVQHVVMTAIQELMSKESVAQSGAEPSGDLEHQ
ENST00000307602         MLQLILGCAVNCEQKQEYIQAIMMMEESVQHVVMTAIQELMSKESPVSAGNDAYVDLDRQ
ENSMUST00000037154      MLQLILGCAVNCEQKQEYIQAIMMMEESVQHVVMTAIQELMSKESPVSAGHDAYVDLDRQ
SINFRUP00000138959      ------------------------------------------------------------
ENST00000264827         LLQLVLGCAISCEKKQDHIQRIMTLEESVQHVVMEAIQELMTKDTPDSLSPETYGNFDSQ
ENSMUST00000005275      LLQLVLGCAISCEKKQEYIQRIMTLEESVQHVVMEAIQELMTKDTPDSLSPENYGNFDTQ
CG10653-RA              LLQLVLGCAVNCAEKQSYITEIMCLEEELQANIMRALQELEATRQASTPEGGVASSLSRG
                        :: :::   :        :  :: :   :   ::  :  :                :   

ENST00000257142         LKRALEELQEALAEKEELRQRCEELDMQVTTLQDEKNSLVSENEMMNEKLDQLDG-----
ENSMUST00000030306      LKRALEELQEAIAEKEELKQRCQELDMQVTTLQDEKNSLVSENEMMNEKLDQLDG-----
SINFRUP00000138525      LKKALEDLAELLAEKEEFSQRCQELDRQVALLHEERNSLLAENDVLTDRANQLD------
ENST00000307602         LKKTTEELNEALSAKEEIAQRCHELDMQVAALQEEKSSLLAENQVLMERLNQSD------
ENSMUST00000037154      LKKTTEELNEALSAKEEIAQRCHELDMQVAALQEEKSSLLAENQILMERLNQSD------
SINFRUP00000138959      ----------------------------VAALQEEKSSLLAENQVLMERLNQSD------
ENST00000264827         SRR-YYFLSEEAEEGDELQQRCLDLERQLMLLSEEKQSLAQENAGLRERMGRPE------
ENSMUST00000005275      SRR-YYFLSEEVEEGDHLQQHYLDLERQLLLLSEEKQNLAQENAALRERVGRSE------
CG10653-RA              SRTGLLDSKAVQEDRDALAQKCFETEKKMLLLIDEKTNLQQELHKLQQEFARLEQHSTVI
                                         :          :  * :*: .*  *   : :.  : :      

ENST00000257142         ----SFDDPNTVVAKKYFHAQLQLEQLQEENFRLEAAKDDYRVHCEELEKQLIEFQHRND
ENSMUST00000030306      ----SFDDPNTMVAKKYFHVQLQLEQLQEENYRLEAAKDDYRVHCEELEKQLIEFQHRND
SINFRUP00000138525      ----TFEDPSTPSGRKHSHLQQQVESLQEETFRLEAAKDDYRIHCEDLEKQLIEVQHRND
ENST00000307602         ----SIEDPNSPAGRRHLQLQTQLEQLQEETFRLEAAKDDYRIRCEELEKEISELRQQND
ENSMUST00000037154      ----SIEDPNSPAGRRHLQLQTQLEQLQEETFRLEAAKDDYRIRCEELEKEISELRQQND
SINFRUP00000138959      ----SIEDINSPAGRRHLQLQTQLEQLQEETFRLEASKDDYRIRCEELEKELLDVKSQNE
ENST00000264827         -----GEGTPGLTAKKLLLLQSQLEQLQEENFRLESGREDERLRCAELEREVAELQHRNQ
ENSMUST00000005275      -----VESAPGLTAKKLLLLQSQLEQLQEENFRLESSREDDRLRCLELEREVAELQQRNQ
CG10653-RA              GDDGVSLGPVQTGSVRYNELRRQLDLLKEELLQSEGAREDLKIKAQQQDTDLLHMQMRIE
                               .     . :    : *:: *:**  : *..::* :::. : : :: ..: : :

ENST00000257142         ELTSLAEETRALKDEIDVLRATSDKANKLESTVEIYRQKLQDLNDLRKQVKTLQETNMMY
ENSMUST00000030306      ELTSLAEETRALKDEIDVLRATSDKANKLESTVEVYRQKLQDLNDLRKQVKSLQETNMMY
SINFRUP00000138525      ELTSLAEESRALKDELDVLRFV--------------------ILNINGDIHFEQAAIMKI
ENST00000307602         ELTTLADEAQSLKDEIDVLRHSSDKVSKLEGQVESYKKKLEDLGDLRRQVKLLEEKNTMY
ENSMUST00000037154      ELTTLADEAQSLKDEIDVLRHSSDKVSKLEGQVESYKKKLEDLGDLRRQVKLLEEKNTMY
SINFRUP00000138959      ELTTLADEAQSLKDEMDVLRHSSDKVTKLEGTVEHYKKKLEDMGLLRRQNKLMEEKNTVL
ENST00000264827         ALTSLAQEAQALKDEMDELRQSSERAGQLEATLTSCRRRLGELRELRRQVRQLEERNAGH
ENSMUST00000005275      ALTSLSQEAQALKDEMDELRQSSERARQLEATLNSCRRRLGELQELRRQVRQLEERNAGH
CG10653-RA              ELMKSSAEVTTLKDEVDVLRESNDKLKICEAQLDTYKKKLEDYNDLKKQVKILEERSADY
                         * . : *  :****:* **                         :. : :  :      

ENST00000257142         MHNTVSLEEELKKANAARTQLETYKRQVQDLHVKLSSESKRADTLAFEMKRLEEKHEALL
ENSMUST00000030306      MHNTVSLEEELKKANAARAQLETYKRQVQDLHTKLSSESKRADTLAFEMKRLEEKHETLL
SINFRUP00000138525      VNFSV--------------------CQVQELHKKMTEETRRADNLAFEMKKLEEKHETVL
ENST00000307602         MQNTVSLEEELRKANAARSQLETYKRQVVELQNRLSEESKKADKLDFEYKRLKEKVDSLQ
ENSMUST00000037154      MQNTVSLEEELRKANAARGQLETYKRQVVELQNRLSDESKKADKLDFEYKRLKEKVDGLQ
SINFRUP00000138959      MQTNVSLEEELRKANAAKGQLETYKRQVVELQNKLSEESKKADKMEFEYKRLKEKVDSLQ
ENST00000264827         AERTRQLEDELRRAGSLRAQLEAQRRQVQELQGQRQEEAMKAEKWLFECRNLEEKYESVT
ENSMUST00000005275      AERTRQLEEELRRAGSLRAQLEAQRRQVQELQGQWQEEAMKAEKWLFECRNLEEKCDLVT
CG10653-RA              VQQNAQFEEDAKRYANTKGQVELFKKEIQDLHAKLDAESSKNVKLEFDNKNLESKNLALQ
                         . .                      :: :*: :   *: :  .  *: :.*:.*   : 

ENST00000257142         KEKERLIEQRDTLKETNEELRCSQVQQDHLNQTDASAT---KSYENLAAEIMPVEYREVF
ENSMUST00000030306      KEKERLIEQRDTLKETNEELRCSKAQQDHLNQADASAT---KSYENLAAEIMPVEYREVF
SINFRUP00000138525      KEKERIIMERESLKEINEELRCSQAQQHQLSQAASSP-----SHDNLAAELIPIEYREKF
ENST00000307602         KEKDRLRTERDSLKETIEELRCVQAQEGQLTTQGLMPLGSQESSDSLAAEIVTPEIREKL
ENSMUST00000037154      KEKDRLRTERDSLKETIEELRCVQAQEGQLTTQGLMPLGSQESSDSLAAEIVTPEIREKL
SINFRUP00000138959      KEKDRMRTERDSLKETIEELHCVQAQEGQLTS-GLLPLTSSGASDSLAAEITTPEMREHL
ENST00000264827         KEKERLLAERDSLREANEELRCAQLQPRGLTQADPSLDPTSTPVDNLAAEILPAELRETL
ENSMUST00000005275      KEKERLLTERDSLREANEELRCAQLQPRGLAQADLSLDPTPSGLENLAAEILPAELRETL
CG10653-RA              RAKDSLLKERDNLREAVDELKCGQLSSN-----------TALTGTTVSRELQPSATVEKL
                        : *: :  :*:.*:*  :**:* : .   :               .:: *: .    * :

ENST00000257142         IRLQHENKMLRLQQEGSENERIEELQEQLEQKHRKMNELETEQRLSKERIRELQQQIEDL
ENSMUST00000030306      IRLQHENKMLRLQQEGTENERIEQLQEQLEQKHRKMNELETEQRLSKERIGELQQQIEDL
SINFRUP00000138525      LRLQHENKMLRVQQEECEREKIAALEAQLEEAHKAQSELDTENRLKQERVGELQRQVEDL
ENST00000307602         IRLQHENKMLKLNQEGSDNEKIALLQSLLDDANLRKNELETENRLVNQRLLEVQSQVEEL
ENSMUST00000037154      IRLQHENKMLKLNQEDSDNEKIALLQSLLDDANLRKNELETENRLVNQRLLEVQSQVEEL
SINFRUP00000138959      IRLQHENKMLKLSQEGSDNEKIALLQSLMEDASRRTSELETENRLINQRLMEEQSQVEEL
ENST00000264827         LRLQLENKRL-CRQEAADRERQEELQRHLEDANRARHGLETQHRLNQQQLSELRAQVEDL
ENSMUST00000005275      VRLQLENKRL-CQQEAADRERQEELQRHLEEANRARHGLEAQQRLNQQQLSELRAQVEEL
CG10653-RA              QRLEAENKALREGQGG-----QTALAQLLDDANKRCENLREQLKTANERILSLSHASQSD
                         **: *** *   *          *   :::       *  : :  :::: .     :. 

ENST00000257142         QKSLQEQGSKSEGESSSKLKQKLEAHMEKLTEVHEELQKKQELIEDLQPDINQ-NVQKIN
ENSMUST00000030306      QKSLQEQGSKSEGESSSKLKQKLEAHMEKLTEVHEELQKKQELIEDLQPDISQ-NAQKIS
SINFRUP00000138525      QKALQSQAVKPD---ESNLKKKLDAHKFQLNEAQDEIMKKKELLEDLQHDS----SLKVD
ENST00000307602         QKSLQDQGSKAE--DSVLLKKKLEEHLEKLHEANNELQKKRAIIEDLEPRFNN-SSLKIE
ENSMUST00000037154      QKSLQDQGSKAE--DSVLLKKKLEEHLEKLHEANNELQKKRAIIEDLEPRFNN-SSLRIE
SINFRUP00000138959      QKSLQEQGSTAE--DSSLLKKKYEENLAKVRELSNEVSKKTSFIDEMELKYSS-STQRVD
ENST00000264827         QKALQEQGGKTE--DSILLKRKLEEHLQKLHEADLELQRKREYIEELEPPTDSSTARRIE
ENSMUST00000005275      QKALQEQGGKTE--DPTLLKRKLEDHLQKLHEADLELQRKREYIEELEPPTDSSTARRIE
CG10653-RA              DPILK------------------ESEFGKQIKQLMELNEQKTLQLEEAVTQSTSLQCKVT
                        :  *:             :    : .  :  :   *: .:     :           :: 

ENST00000257142         ELEAALQKKDEDMKAMEERYKMYLEKARNVIKTLDPKLNP---ASAEIMLLRKQLAEKER
ENSMUST00000030306      ELEAALQKKDEDMKAMEERYKMYLEKARNVIKTLDPKLNP---ASAEIMLLRKQLAEKER
SINFRUP00000138525      ELMAALKKKDDDMRAMEERYKMYLEKARNVIRALDPKLNP---ATAEIQALRNQLGEREK
ENST00000307602         ELQEALRKKEEEMKQMEERYKKYLEKAKSVIRTLDPKQNQG--AAPEIQALKNQLQERDR
ENSMUST00000037154      ELQEALRKKEEEMKQMEERYKKYLEKAKSVIRTLDPKQNQG--AAPEIQALKNQLQERDR
SINFRUP00000138959      ELEEALKKKDEDMKQMEERYKKYLEKAKSVIRTLDPKQNQG--SGPEVQALKNQLQEKER
ENST00000264827         ELQHNLQKKDADLRAMEERYRRYVDKARMVMQTMEPKQRPAAGAPPELHSLRTQLRERDV
ENSMUST00000005275      ELQDSLQKKDADLRAMEERYRRYVDKARTVIQTLEPKQRPPTVVSPEFHTLSPTQP---L
CG10653-RA              QLETNLSAREQEILVYDAKYRKCVEKAKEVIKSIDP-------------RIASALDASVL
                        :*   *  :: ::   : :*:  ::**: *:::::*           .  :         

ENST00000257142         RIEILESECKVAK-FRDYEEKLIVSAWYNKSLAFQKLGMESRLVSGGGACSDTGACTPAR
ENSMUST00000030306      RIEILESECKVAK-LRDYEEKLIVSAWYNKSLAFQKLGMESRLVSGASACKDSVAAAPAR
SINFRUP00000138525      QNATLERQCEQAR-VREYEEKMIVTAWYNKSLNFQKLAMESRLGG-------CPPAGPTQ
ENST00000307602         LFHSLEKEYEKTKSQREMEEKYIVSAWYNMGMTLHKKAAEDRLAS----------TGSGQ
ENSMUST00000037154      LFHSLEKEYEKTKSQRDMEEKYIVSAWYNMGMTLHKKAAEDRLAS----------TGSGQ
SINFRUP00000138959      MLHSLEKEMDKAKGQRDYEEKMIVSAWYNMGISLQKMAAEDRLAN----------TGSGQ
ENST00000264827         RIRHLEMDFEKSRSQREQEEKLLISAWYNMGMALQQRAGEERAPA------------HAQ
ENSMUST00000005275      TLVSWQMDYEKSRRRQEQEEKLLISAWYSMGMALEHRAGEEHAPA------------HAQ
CG10653-RA              EKSADLVEEEPKPKMSVMEEQLMTSAFYRLGVNAQRDAIDSKLAILMG---------SGQ
                               : .        **: : :*:*  .:  .: . :.:                 :

ENST00000257142         SFLAQQRHITNT-RRNLSVKVPATTSD-----
ENSMUST00000030306      SFLAQQRHITNT-RRNLSVKVPAAASD-----
SINFRUP00000138525      SFLSQQRQVANTPRRGLSVNTSATTS------
ENST00000307602         SFLARQRQATSS-RRSYPGHVQPATAR-----
ENSMUST00000037154      SFLARQRQATST-RRSYPGHVQPATAR-----
SINFRUP00000138959      SFLARQRQATSA-RRTYPGHVQPASAR-----
ENST00000264827         SFLAQQRLATNS-RRGPLGRLASLNLRPTDKH
ENSMUST00000005275      SFLAQQRLATNA-RRGPLGRQA-LSLRPTDKH
CG10653-RA              TFLARQRQSAPR--KSLSAMKSK---------
                        :**::**  :    :