CLUSTAL W (1.82) multiple sequence alignment


ENST00000303641         MARGSALPRRPLLCIPAVWAAAALLLSVSRTSGEVEVLDPNDPLGPLDGQDGPIPTLKGY
ENSMUST00000021918      MARGWVRPSRVPLCARAVWTAAALLLWTPWTAGEVEDSEAIDTLGQPDGPDSPLPTLKGY
SINFRUP00000131718      ----------------------------------------------------------GY
SINFRUP00000134550      ------------------------------------------------------------
CG4926-RA               ------------------------------------------------------MNKYSA
ci0100146108            ---------------------------------------------MTFIDQLFVVLDPDM
                                                                                    

ENST00000303641         FLNFLEPVNNITIVQGQTAILHCKVAGNPPPNVRWLKN-DAPVVQEPRRIIIRKTEYGSR
ENSMUST00000021918      FLNFLEPVNNITIVQGQTAILHCKVAGNPPPNVRWLKN-DAPVVQEPRRVIIRKTEYGSR
SINFRUP00000131718      FLEFQEPVNNITHFQGQTATLHCKVTGNPRPTIRWLKN-DAPLVQEQGRITIRKTEAGSK
SINFRUP00000134550      FIRLEAPMNNITTSLGHTAELFCRVSGNPPPAVRWLKN-DAPVVQEPRRISYRSTLYGSR
CG4926-RA               FIVCISLVLLFTKKDVGSHNVDSRIYGFQQSSGICHIY-NGTICR--DVLSNAHVFVSPN
ci0100146108            ELNLMEDMVNQTLQSGGKAIFRCKVEGTPTDAVIFTWYKDGTELVDDPRFNIRTKSWGSL
                         :     :   *     .  . .:: *            :..       .       .. 

ENST00000303641         LRIQDLDTTDTGYYQCVATNGMKTITATGVLFVRLGPTHSPNHNFQDDYHEDGFCQPYRG
ENSMUST00000021918      LRIQDLDTTDTGYYQCVATNGLKTITATGVLYVRLGPTHSPNHNFQDDDQEDGFCQPYRG
SINFRUP00000131718      LRIQDLDTTDTGYYQCVASNTLRVISATGVLYVKMG--QMPTHGPDRPSPDKGFCQPYRG
SINFRUP00000134550      LRIRNLDTTDTGYFQCVATNSQGTVSTTGVLFVKFG------------------------
CG4926-RA               LTMNDLEERLKAAYGVIKESKDMNANCRMYALPSLCFSSMP---------------ICRT
ci0100146108            LKISDVYTADSGQYRCEASNTYRRVATSAYLTVSFEAPPDSGISHVDPEYVKGRCEQYTG
                        * : ::    .. :     .              :                         

ENST00000303641         IACARFIGNRTIYVDSLQMQGEIENRITAAFTMIGTSTHLSDQCSQFAIPSFCHFVFPLC
ENSMUST00000021918      IACARFIGNRTIYVDSLQMQGEIENRITAAFTMIGTSTQLSDQCSQFAIPSFCHFVFPLC
SINFRUP00000131718      IACARFIGNQSIYVESPQMQGESENRITAAFTMIGTSAQMSDQCSKFAVRSLCFYVFPLC
SINFRUP00000134550      -KCLCFIG----QIVALHLFPQLSLATASAFTMIGTSNHLSDRCSQFAIPSLCHFAFPTC
CG4926-RA               PERTNLLYFANVATNAKQLKNVSIRRKRTKSKDIKNISIFKKKSTIYED-VFSTDISSKY
ci0100146108            FACSRFLQGQYVYLEFFQKQENVEQVVSTALQFLANLKDVSPSCSTYAPAAFCYYFFSPC
                             ::          :          :    : .   ..  .: :    :.    .  

ENST00000303641         DARSR------TPKPRELCRDECEVLESDLCRQEYTIARSNPLILMRLQLPKCEALPMPE
ENSMUST00000021918      DARSR------APKPRELCRDECEVLENDLCRQEYTIARSNPLILMRLQLPKCEALPMPE
SINFRUP00000131718      DEGSR------VPRQRQLCRDECEALEHDLCSLEYTVARSNPMILMQLQLPRCHLLPQPG
SINFRUP00000134550      DRSSG------TDKPRDLCRDECEILENDLCKTEYIIARSNPIILKRLKLPNCEDLAASD
CG4926-RA               PPTRE------SENLKRICREECELLENELCQKEYAIAKRHPVIGMVG-VEDCQKLP---
ci0100146108            KKNDLGDVIMADPQPLRLCQEDCDLLKHKTCKNEFFNQNADKFSPRVFETSDCSSLPR-T
                                     .   :*:::*: *: . *  *:   . . .         *  *.   

ENST00000303641         SPDAANCMRIGIPAER-LGRYHQCYNGSGMDYRGTASTTKSGHQCQPWALQHPHSHHLSS
ENSMUST00000021918      SPDAANCMRIGIPAER-LGRYHQCYNGSGADYRGMASTTKSGHQCQPWALQHPHSHRLSS
SINFRUP00000131718      TPDAASCMRIGIPPEN-LSPYESCYSGSGAGYRGTLSVTRSGYQCQPWSAQYPHSHHLS-
SINFRUP00000134550      SPAAANCLRIGIPMADPINKNHKCYNSSGADYRGTVSVTKSGRQCQPWNSQYPHSHTYLA
CG4926-RA               --QHKDCLSLGITIEV--DKTENCYWEDGSTYRGVANVSASGKPCLRWSWLMK-----EI
ci0100146108            TPTNDHCTTIGLPSVV--NRQHMCYNGTGAKYRGTLSVASTGETCKNWPADML-------
                              *  :*:.    :.  . **   *  ***  ..: :*  *  *            

ENST00000303641         TDFPELGGGHAYCRNPGGQMEGPWCFTQN-KNVRMELCDVPSCSPRD-------SSKMGI
ENSMUST00000021918      TEFPELGGGHAYCRNPGGQMEGPWCFTQN-KNVRVELCDVPPCSPRD-------GSKMGI
SINFRUP00000131718      QEYPELWHSHNFCRNPGDQMMAPWCFTLD-PQVRFDLCDLQPCTPPE-------NMRKDI
SINFRUP00000134550      VRYPELNGGHSYCRNPGNKHEAPWCFTLD-EGVRMELCDIPICDHKDKP----GGSNMEI
CG4926-RA               SDFPELIG-QNYCRNPGSVENSPWCFVDSSRERIIELCDIPKCADKIWIAIVGTTAAIIL
ci0100146108            FEYSYLAGGHNFCRNPGASLPSPWCYVDT-ALTKKEVCQVPKCNFEKGG---ADGGNGDL
                          :. *   : :*****    .***:.        ::*::  *                :

ENST00000303641         LYILVPSIAIPLVIACLFFLVCMCRNKQKASASTPQR------------RQLMASPSQDM
ENSMUST00000021918      LYILVPSIAIPLVIACLFFLVCMCRNKQKASASTPQR------------RQLMASPSQDM
SINFRUP00000131718      LFILVPAVSIPLVVACLFFLVCSCRHKKQPSSDSPAH------------CQLSSSPHQDV
SINFRUP00000134550      LYILIPSVAIPLAIALLFFFICVCRNNQK-SSRPPVP------------RQPKPVRGQNV
CG4926-RA               IFIIIFAIILFKRRTIMHYGMRNIHNINTPSADKNIYGNSQLNNAQDAGRGNLGNLSDHV
ci0100146108            VMILIPAVSIPLLLGCVIIVFCVACRRKKKTNKNNKG-----------------TPMETR
                        : *:: :: :      :   .    . :  :                          :  

ENST00000303641         EMPLIN-QHK-QAKLKEISLSAVRFMEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLK
ENSMUST00000021918      EMPLIS-QHK-QAKLKEISLSTVRFMEELGEDRFGKVYKGHLFGPAPGEPTQAVAIKTLK
SINFRUP00000131718      ELSLLS-QHKAQVKLQEINMSSLRFIEELGEDRFGKVYKGHLYGFTASEPMQLVTIKTVR
SINFRUP00000134550      EMSMLTTAYKPKSKAKELPLSAVRFMEELGDCPLGKIYKGHLYLPG-MDQAQLVAIKTLK
CG4926-RA               ALNSKLIERNTLLRINHFTLQDVEFLEELGEGAFGKVYKGQLLQPN--KTTITVAIKALK
ci0100146108            TLSAKK------AKVPELSSNMVHVIGELGDGKFGKVFKAQILSNLHYCPNEPVSVKTLN
                         :           :  .:  . :..: ***:  :**::*.::           *::*::.

ENST00000303641         DKAEGPLREEFRHEAMLRARLQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSP
ENSMUST00000021918      DKAEGPLREEFRQEAMLRARLQHPNIVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSP
SINFRUP00000131718      DRGDLTLCEEFRQEALLHFQLQHQNIVCLLGVVTKEQPMSMVFSSSSLGDLHEFLVMRSP
SINFRUP00000134550      DVSSTQQWNEFQKEAAVLTELQHPNVVCLLGVVTQEQPVCMLFEFLPQGDLHEFLIMRSP
CG4926-RA               ENASVKTQQDFKREIELISDLKHQNIVCILGVVLNKEPYCMLFEYMANGDLHEFLISNSP
ci0100146108            DRSTPPQVQEFQREMETFSELQHANVACLKAVVTQPSLRCMVFEYTNGVDLHEYLVLHSP
                        : .     ::*::*      *:* *:.*: .** : .  .*:*.     ****:*: .**

ENST00000303641         HSDVG--STDDDRTVKSALEPPDFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLN
ENSMUST00000021918      HSDVG--STDDDRTVKSALEPPDFVHVVAQIAAGMEFLSSHHVVHKDLATRNVLVYDKLN
SINFRUP00000131718      NSDIG--SSDDDKTFKSTLEQADFLHILTQVAAGMEYLSSKQVVHKDLAARNILVFDKLS
SINFRUP00000134550      HSDVGC-SSDEDGTVKSTLDHGDFLHMAIQVTAGMEYLASHNYVHKDLAARNVLVGEQLH
CG4926-RA               -------------TEGKSLSQLEFLQIALQISEGMQYLSAHHYVHRDLAARNCLVNEGLV
ci0100146108            QADFAKPPSSASSHASSSIEHADFIRMAIQVASGMDYLTRNNFIHRDLSARNVLVCGNLD
                           .            .::.  :*:::  *:: **::*: :: :*:**::** **   * 

ENST00000303641         VKISDLGLFREVYAADYYK-LLGNSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFS
ENSMUST00000021918      VRISDLGLFREVYSADYYK-LMGNSLLPIRWMSPEAVMYGKFSIDSDIWSYGVVLWEVFS
SINFRUP00000131718      IKILNLGFSRNVYSADYYS-LMGASSFPIRWMSPEAIMYRKFSTDSDIWSYGVLLWETFS
SINFRUP00000134550      VKISDLGLSREIYSSDYYC-LQPKTLLPIRWMPPEAITYGKFTSDSDIWSFGVVLWEMFS
CG4926-RA               VKISDFGLSRDIYSSDYYR-VQSKSLLPVRWMPSESILYGKFTTESDVWSFGVVLWEIYS
ci0100146108            LKICNLGVIRDSYLSCYYRNPQGGQMLPIRWMAPESLKTWQFSDKSAVWSFGVLLWEMFS
                        ::* ::*. *: * : **        :*:***..*::   :*: .* :**:**:*** :*

ENST00000303641         YGLQPYCGYSNQDVVEMIRNRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDIHSRLR
ENSMUST00000021918      YGLQPYCGYSNQDVVEMIRSRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDIHSRLR
SINFRUP00000131718      YGLQPYCGYSNQEVIEMVCSYQLLHCPDDCPGWIYTLMLECWSQLPAGRPHFKDIHMRLR
SINFRUP00000134550      YGLQPYYGFSNQEVMEMVRKRQLLPCPEDCPPRFYGLMTECWQEGPARRPRFKDIHTRLR
CG4926-RA               YGMQPYYGFSNQEVINLIRSRQLLSAPENCPTAVYSLMIECWHEQSVKRPTFTDISNRLK
ci0100146108            YGLQPYCGYSNHEVLDMISRRQLLTCPDQCPAKVYSLMHECWCGQPAQRPTFADLHSKLA
                        **:*** *:**::*::::   *:* .*::**  .* ** ***   .  ** * *:  :* 

ENST00000303641         AWGNLSNYNSSAQTSGA--SNTTQTSSLSTSPVSN-----VSNARYVGPKQ----KAPPF
ENSMUST00000021918      SWGNLSNYNSSAQTSGA--SNTTQTSSLSTSPVSN-----VSNARYMAPKQ----KAQPF
SINFRUP00000131718      CLETLSDSTNSAQMSGS--SNNTQLSHVSTSPASHNGISAINAFHYMSPK-----KGSPF
SINFRUP00000134550      AWEGMSSHASSSTPSGGGGNATTQTTSLSASPVSN-----LSNQRFAAAPAGYLYPAQAI
CG4926-RA               TWHEGHFKASNPEM----------------------------------------------
ci0100146108            GWEGTSTTRMTSQLAQGIHRQLTNVMKEGGGQYAPYAQQQQRPVMMNDPGINKPPQPYSA
                                  ..                                                

ENST00000303641         PQPQFIPMKGQIRPMVPPP--QLYVPVNGYQPVPAYGAYLPNFYPVQIPMQMAPQQVPPQ
ENSMUST00000021918      PQPQFIPMKGQIRPLVPPA--QLYIPVNGYQPVPAYGAYLPNFYPVQIPMQMAPQQVPPQ
SINFRUP00000131718      HQPQFMPMVGQIHQLKVPP--PIYIP--GYQSMPSY-PYLPNFYPMQIPL---PIHHPNQ
SINFRUP00000134550      ASPGQMAQITAWTPMAVSQTHQRFIPVNGYPIPTGYAAFPAHFAPPVAPTKVIQHHLPP-
CG4926-RA               ------------------------------------------------------------
ci0100146108            SPTSGFLTSSPPGAPNTSPASRLYQSPGTASSSAHSAGFYNQQHPQYQPEHPYPQQNRYL
                             :                                                      

ENST00000303641         MVPKPSSHHSGSGSTSTGYVTTAPSNT---------------SMADRAALLSEGADDTQN
ENSMUST00000021918      MVPKPSSHHSGSGSTSTGYVTTAPSNT---------------SVADRAALLSEGTEDAQN
SINFRUP00000131718      LVPKAGSHHNGSGSTSPGCVTVAPSNT---------------SVTEMPALLNE-DKTSEE
SINFRUP00000134550      --PKSRSPSSASGSTSTGHVSGVPSTTG--------------SNHDANTPLLSHCIMQGG
CG4926-RA               ------------------------------------------------------------
ci0100146108            NPPHPNQHYSSNQSRSSGSCASSEYNHPPHLRVLPSHQEQREPFQQSPLPYPPPQEAMNR
                                                                                    

ENST00000303641         APEDGAQSTVQEAEEEEE--GSVPETELLGDCDTLQVDEAQ-VQLEA-------------
ENSMUST00000021918      IAEDVAQSPVQEAEEEEE--GSVPETELLGDNDTLQVTEAAHVQLEA-------------
SINFRUP00000131718      LMDGMSRNRLDQSRD-----LSVAETELLSEAESPQTEE---------------------
SINFRUP00000134550      GGQGYGQKGVGQLDHSQTSALLASDSDVLMYNDTIITADL--------------------
CG4926-RA               ------------------------------------------------------------
ci0100146108            RQESVNQHQFHHPEQQRVYGNIENTSHDDQSEDSALLSRSRPGSGVRPDRIPLSVYKDQS
                                 .                                                  

ENST00000303641         ------------------------------------------------------------
ENSMUST00000021918      ------------------------------------------------------------
SINFRUP00000131718      ------------------------------------------------------------
SINFRUP00000134550      ------------------------------------------------------------
CG4926-RA               ------------------------------------------------------------
ci0100146108            ESYPPSSPDRMKPLLAPKPPAYNTVMEEMNKQTSHGDSRQHRRQGSGPHPGAQGIPPLPN
                                                                                    

ENST00000303641         ------------------------------------------------------------
ENSMUST00000021918      ------------------------------------------------------------
SINFRUP00000131718      ------------------------------------------------------------
SINFRUP00000134550      ------------------------------------------------------------
CG4926-RA               ------------------------------------------------------------
ci0100146108            DDSRARNTDSASGKATSCDSGLPCDDVDIDESADLSRPMLPPNGQSPSRIVGKTGPQSAG
                                                                                    

ENST00000303641         -----------------
ENSMUST00000021918      -----------------
SINFRUP00000131718      -----------------
SINFRUP00000134550      -----------------
CG4926-RA               -----------------
ci0100146108            SSVSGSTQVTAETRISA