CLUSTAL W (1.82) multiple sequence alignment


ENSMUST00000005057      ---------------GELRGDPD---------------------RTGVRTRGG--PSPPR
ENST00000307741         ------------ACPGSAGGGPLGPQAAVAAVAAVGPRQAASVAEVAGRVAGGRREGAAG
SINFRUP00000165285      ------------------------------------------------------------
ENSMUST00000022223      RSGLLRSARSRLPGSQTPPPASCTYQAGGPRASCCRPPGLPMITLCLSALRGLHRAGGSR
ENST00000242866         -----------------------------------------MIARCLLAVRSLRRVGGSR
SINFRUP00000139045      ------------------------------------------------------------
ci0100146871            -----------MNVALKVVSSRLPYKFASLFVKCVTCVDNPTIRSRTFFTQSKKNHRNAC
ENST00000028585         -------------------------MLCVGRLGGLGARAAALPPRRAGRGSLEAGIRARR
CG7791-RA               -------------------------MLEFGRT---------LLRWRTRHCS-------RR
                                                                                    

ENSMUST00000005057      AQPTAMKPPAACAGDVVDAASPASTVNHLRWDLSAQQIRALTTQLIEQTKCVYDRVGAQN
ENST00000307741         ADPPAMKPPAACAGDMADAASPCSVVNDLRWDLSAQQIEERTRELIEQTKRVYDQVGTQE
SINFRUP00000165285      --------------------APVCSVNRLRWDLSPDQISQLANELIRDTKKVYDGVGALD
ENSMUST00000022223      IRLRMTLGREAASPLQAMSSYTAAGRNVLRWDLSPEQIRTRTEELIAQTKQVYDTVGTIN
ENST00000242866         ILLRMTLGREVMSPLQAMSSYTVAGRNVLRWDLSPEQIKTRTEELIVQTKQVYDAVGMLG
SINFRUP00000139045      ------------------------------------------------------------
ci0100146871            IAIRASNNIRSFASVLTTMVQPLQNQ---RWDLSAKEIKEQADALMESMKAVYDQVAAVS
ENST00000028585         VSTSWSPVGAAFNVKPQGSRLDLFGERRGLFGVPELSAPEGFHIAQEKALRKTELLVDRA
CG7791-RA               VST-WTPLATAFNAPP-ARRINFTHDDVGLFGMPELRSFEGFYLLRDNVESRTQELISEA
                                                                                    

ENSMUST00000005057      FEDVSYESTLKALADVEVTYTVQRNILDFPQHVSPCKDIRAASTEADKKLSEFDVEMSMR
ENST00000307741         FEDVSYESTLKALADVEVTYTVQRNILDFPQHVSPSKDIRTASTEADKKLSEFDVEMSMR
SINFRUP00000165285      LDGVTFENTLKALADVEVEYTVQRNMLDFPQHVSPCKEVRAASTEADKRLSEFDVEMSMR
ENSMUST00000022223      LEDVTYENCLQVLADIEVKYIVERTMLDFPQHVSSDREVRAASTEADKRLSRFDIEMSMR
ENST00000242866         IEEVTYENCLQALADVEVKYIVERTMLDFPQHVSSDKEVRAASTEADKRLSRFDIEMSMR
SINFRUP00000139045      -----------------------RHVLDFPQYVSPSKEVRAASTEADKQLSEFDVELSMR
ci0100146871            VHEATFENSILPISNLDVTSSVIRNNLDFYQHVHTNKELRDASTECDKKLSEFEIELSMR
ENST00000028585         CSTPPGPQTVLIFDELSDSLCRVADLADFVKIAHPEPAFREAAEEACRSIGTMVEKLNTN
CG7791-RA               TSDQRRRKMVDIFDELSDSLCKVADLAEFVRIAHPQSRYTQAAEQACISICGMVESLNTH
                                                   :* : . .      *: :.   :  :  .:. .

ENSMUST00000005057      QDVYQRVVWLQEKTPKDSLKPEAARYLERLIKLG-RRNGLHLPQDTQEKIKNIKKRLSLL
ENST00000307741         EDVYQRIVWLQEKVQKDSLRPEAARYLERLIKLG-RRNGLHLPRETQENIKRIKKKLSLL
SINFRUP00000165285      EDVYRRVVALEKQLDARSLNAESRRYLDRLLKLG-RRNGLHLAPETQEEIKNIKKKLSNL
ENSMUST00000022223      EDVFQRIVHLQETCDLEKIKPEARRYLEKSIKMG-KRNGLHLPEHVKNEIKSMKKRMSEL
ENST00000242866         GDIFERIVHLQETCDLGKIKPEARRYLEKSIKMG-KRNGLHLPEQVQNEIKSMKKRMSEL
SINFRUP00000139045      EDVFRRIVALQENTP-ENISAEEKRLLDRLVTLG-RRKGLHLPKDTQEEIKKTSKLISEL
ci0100146871            KDVYDRVVAVE--GSNMQCSNEGKRLVTRMVKLG-KRNGLHLDDETQAKIKANKKRQTEI
ENST00000028585         VDLYQSLQKLLADKKLVDSLDPETRRVAELFMFDFEISGIHLDKEKRKRAVDLNVKILDL
CG7791-RA               KPIYKALSHVVDHGDKLPTSEVD-RHVSRLFLFDFEQCGIHLPEEERMRVVRLNDYILQL
                          ::  :  :              * : . . :. .  *:**  . : .    .     :

ENSMUST00000005057      CIDFNKNLNEDTTFLPFTREELGGLPEDFLSSLEKAEDG--KLKVTLKYPHYFPLLKKCH
ENST00000307741         CIDFNKNLNEDTTFLPFTLQELGGLPEDFLNSLEKMEDG--KLKVTLKYPHYFPLLKKCH
SINFRUP00000165285      CIDFNKNLNEDTTSLSFSREQLGGLPEDFLSSLEKDGD---KLKVTLKYPHYFPTIKKCF
ENSMUST00000022223      CIDFNKNLNEDDTSLVFSKAELGALPDDFIDSLEKTDED--KYKVTLKYPHYFPVMKKCC
ENST00000242866         CIDFNKNLNEDDTFLVFSKAELGALPDDFIDSLEKTDDD--KYKITLKYPHYFPVMKKCC
SINFRUP00000139045      SIEFNRNLNEDTTSLEFSERELGGMADSYLDGLEKTADG--RYRVTLEYPHYYPLMKRCH
ci0100146871            GIDFQKNLNEESEKLLFEPEQLAGLPNDFIKSLNKDKDSGSKLVVTLKYPHYFPIMKKCS
ENST00000028585         SSTFLMGTNFPN------KIEKHLLPEHIRRNFTSAGDH-------------IIIDGLHA
CG7791-RA               GQKFMSGAVQPS------VLPRSQVPESFRNYFPTSGEN-------------VIITGLCT
                           *  .       : :       :.:     : .  :      : :             

ENSMUST00000005057      VPETRRLLEEAFNCRCKEE--------------------------------NCAILKELV
ENST00000307741         VPETRRKVEEAFNCRCKEE--------------------------------NCAILKELV
SINFRUP00000165285      IPETRQKLEEAFNSRCKEE--------------------------------NSAILKELV
ENSMUST00000022223      VPETRRKMEMAFHTRCKEE--------------------------------NTIILQQLL
ENST00000242866         IPETRRRMEMAFNTRCKEE--------------------------------NTIILQQLL
SINFRUP00000139045      DPETRRKMETAFHSRCKEVTGVLGTDLGTLHSHLSFKRLLFLLLFYFFAKVNTAILEQLV
ci0100146871            VSQTRKVLETAFNSRCKEQ--------------------------------NSAILAELV
ENST00000028585         ESPDDLVREAAYKIFLYPNAG------------------------------QLKCLEELL
CG7791-RA               NAENVQMREAAYRLYLQPSKS------------------------------QEDLLRDLL
                         .      * *:.        ::   :  :   : :  ::::::: ::  ::   * :*:

ENSMUST00000005057      SLRAQKSSLLGFHTHADYVLEMNMAKTSQTVATFLDELAQKLKPLGEQERAVILELKEAE
ENST00000307741         TLRAQKSRLLGFHTHADYVLEMNMAKTSQTVATFLDELAQKLKPLGEQERAVILELKRAE
SINFRUP00000165285      RLRAQKSALLGFSTHADFILEMNMAKSGKKVAVFLEELARKLKPLGDEERTTILQLKEKE
ENSMUST00000022223      PLRAQVAKLLGYNTHADFVLELNTAKSTSHVATFLDDLSQKLKPLGEAEREFILSLKKKE
ENST00000242866         PLRTKVAKLLGYSTHADFVLEMNTAKSTSRVTAFLDDLSQKLKPLGEAEREFILNLKKKE
SINFRUP00000139045      QLRSKVADLLGYSSHANYVLEINMAKNASHVSDFLNTFHERLKPVGMKERKYILSLKRRE
ci0100146871            KLRAEKAAILGYENHAAFVHDMRMAKHPDNVIKFTNELAEKLQPLGKCDRDEMLRLKKVE
ENST00000028585         SSRDLLAKLVGYSTFSHRALQGTIAKNPETVMQFLEKLSDKLSERTLKDFEMIRGMKM--
CG7791-RA               LCRHELARSCGFDTYAHRALKGSTMEKPEVVREFIDELSEKLRPRADCDFALMSQMKR--
                          *   :   *: ..:    .    :  . *  * : :  :*      :   :  :*   

ENSMUST00000005057      CAKRGLPFDGRIHAWDMRYYMNQVEETRYRVDQNLLKEYFPMQVVTRGLLAIYQELLGLT
ENST00000307741         CERRGLPFDGRIRAWDMRYYMNQVEETRYCVDQNLLKEYFPVQVVTHGLLGIYQELLGLA
SINFRUP00000165285      SQKRNLPFSGELHAWDMRYYMTQVEETQYAVDQNLLKEYFPMEVVTQGLLAIYQELLGLS
ENSMUST00000022223      CEERGFAYDGKINAWDLHYYMTQTEELKYSVDQESLKEYFPIEVVTEGLLSIYQELLGLS
ENST00000242866         CKDRGFEYDGKINAWDLYYYMTQTEELKYSIDQEFLKEYFPIEVVTEGLLNTYQELLGLS
SINFRUP00000139045      CLMKGLLFDGQINAWDLPYYMNQVEQCKFAVNKDKLIEYFPLDLVTKGLLAIYQELLGLT
ci0100146871            CKNGNEEFDGVINMWDLRYFMTKIEEMKYSVDHDKLKQYFPIHIVTKGLLNIYQELLGLR
ENST00000028585         --KLN-PQNSEVMPWDPPYYSGVIRAERYNIEPSLYCPFFSLGACMEGLNILLNRLLGIS
CG7791-RA               --REGGKADARAEVWDTPYYTNQLRRQLFEEHANEFLPYFSLGGCMEGLDNLLHALYGIR
                            .   ..    **  *:    .   :  . .    :*.:    .**    : * *: 

ENSMUST00000005057      FTLEEG--AAAWHEDVRLYSVRDAASGEEIGKFYLDLYPREGKYGHAACFGLQPGCLRQD
ENST00000307741         FHHEEG--ASAWHEDVRLYTARDAASGEVVGKFYLDLYPREGKYGHAACFGLQPGCLRQD
SINFRUP00000165285      FQLVDG--APVWHPDVTLYSVTDRATSQVMGQFYLDLYPREGKYGHAACFGLQPGCLLPD
ENSMUST00000022223      FEQVAD--AHVWNKSVSLYTVKDKATGEVLGQFYLDLYPREGKYNHAACFGLQPGCLLPD
ENST00000242866         FEQMTD--AHVWNKSVTLYTVKDKATGEVLGQFYLDLYPREGKYNHAACFGLQPGCLLPD
SINFRUP00000139045      FAEVER--AHVWHEGVKLYTAQDAETGEEVGRFYLDLHPREGKYGHAACFGLQPGCTGPD
ci0100146871            YEQVDD--AHVWHEDVTLYSVKDDASEKLIGHFFLDLHPREGKYGHAACFDLIPGCLKAD
ENST00000028585         LYAEQPAKGEVWSEDVRKLAVVHESEG-LLGYIYCDFFQRADKPHQDCHFTIRGGRLKED
CG7791-RA               LQNTDLKPGEAWHNDIYKLAVVHEREG-LLGYIYCDFYERVGKPNQDCHFTIQGGKRMPD
                                . .*  .:   :. .      :* :: *:. * .*  : . * :  *    *

ENSMUST00000005057      GSRQLAVAAMVANFTKPTPDAPSLLQHDEVETYFHEFGHVMHQLCSQAEFAMFSGTHVER
ENST00000307741         GSRQIAIAAMVANFTKPTADAPSLLQHDEVETYFHEFGHVMHQLCSQAEFAMFSGTHVER
SINFRUP00000165285      GTRQMSVAAMVANFSKPTAEAPSLLQHDEVETYFHEFGHVMHQLCAEADYAMFSGTHVER
ENSMUST00000022223      GSRMMSVAALVVNFSQPIAGRPSLLRHDEVRTYFHEFGHVMHQICAQTDFARFSGTNVET
ENST00000242866         GSRMMAVAALVVNFSQPVAGRPSLLRHDEVRTYFHEFGHVMHQICAQTDFARFSGTNVET
SINFRUP00000139045      GERRLPVAAMIANFTKPRKGWPSLLQHHEVETYFHEFGHVMHEICSKTAFSEFSGTQVET
ci0100146871            GTRQLAVAAMVANFTKPTSDAPSLLTHDEVETFFHEFGHVMHQICAEAEYEMFSGTSVEC
ENST00000028585         GDYQLPVVVLMLNLPRSSRSSPTLLTPSMMENLFHEMGHAMHSMLGRTRYQHVTGTRCPT
CG7791-RA               GSYQLPVVVVMLGLAQPRWSGPTLLSPARLDNLFHEMGHAMHSMLARTEHQHVTGTRCST
                        *   :.:..:: .:.:.    *:**    : . ***:**.**.: ..: .  .:**    

ENSMUST00000005057      DFVEAPSQMLENWVWEKEPLMRMSQHYRTGSEAPQDLLEKLIKSRQANAGLFNLRQIVLA
ENST00000307741         DFVEAPSQMLENWVWEQEPLLRMSRHYRTGSAVPRELLEKLIESRQANTGLFNLRQIVLA
SINFRUP00000165285      DFVEAPSQMLENWVWEREPLLRMSRHYKTGAAIPDDLIDKLIKSRLANTGLFNLRQIVLA
ENSMUST00000022223      DFVEVPSQMLENWVWDIDSLRKLSKHYRDGHPITDELLEKLVASRLVNTGLLTLRQIVLS
ENST00000242866         DFVEVPSQMLENWVWDVDSLRRLSKHYKDGSPIADDLLEKLVASRLVNTGLLTLRQIVLS
SINFRUP00000139045      DFVEVPSQVLENWVWEKEPLRRMSGHYRDGAPIPEDMLDKLIASRVANTGLMNLRQVVLS
ci0100146871            DFVEAPSQMLENWCWEYEPLKQMSQHYEDGSEIPQKLIESLIKSRNANTGVFYLRQIVLG
ENST00000028585         DFAEVPSILMEYFANDYRVVNQFARHYQTGQPLPKNMVSRLCESKKVCAAADMQLQVFYA
CG7791-RA               DFAEVPSVLMEYFAGDPRVLRTFARHFQTHEPISEDMLRRLCASKNLFAASETQLQVFYS
                        **.*.** ::* :  :   :  :: *:.     . .::  *  *:   :.     *:. .

ENSMUST00000005057      KVDQVLHTQT---DADPAEEYARLCQEILGVPATPGTNMPATFGHLAGGYDAQYYGYLWS
ENST00000307741         KVDQALHTQT---DADPAEEYARLCQEILGVPATPGTNMPATFGHLAGGYDAQYYGYLWS
SINFRUP00000165285      KVDQALHTRE---GVDPAEEYARLCGEILGIPASPGTNMPATFGHLAGGYDAQYYGYLWS
ENSMUST00000022223      KVDQSLHTNA---SLDAASEYAKYCTEILGVAATPGTNMPATFGHLAGGYDGQYYGYLWS
ENST00000242866         KVDQSLHTNT---SLDAASEYAKYCSEILGVAATPGTNMPATFGHLAGGYDGQYYGYLWS
SINFRUP00000139045      KVDQTLHSSP---RADTSEVFAKHCEEILGVPATPGTNMTASFGHLAGGYDGQYYSYLWS
ci0100146871            TLDLNIHMCD---HADIVQVYADACKNILCIPATEGTCMPATFGHLAGGYDAQYYGYLWS
ENST00000028585         TLDQIYHGKHPLRN-STTDILKETQEKFYGLPYVPNTAWQLRFSHLVG-YGARYYSYLMS
CG7791-RA               ALDQEYHGASARHGQSSTDTLRSVQDHYYGLPYVDNTAWQLRFSHLVG-YGAKYYAYLVS
                         :*   *        .  .       .   :.   .*     *.**.* *..:**.** *

ENSMUST00000005057      EVYSMDMFHTRFKQEGVLSPKVGMDYRTSILRPGGSEDASAMLKQFLGRDPKQDAFLLSK
ENST00000307741         EVYSMDMFHTRFKQEGVLNSKVGMDYRSCILRPGGSEDASAMLRRFLGRDPKQDAFLLSK
SINFRUP00000165285      EVFSMDMFFTRFKQEGIMNAKVGLDYRKFILRPGGSADASEMLRNFLGREPKQEAFLLSK
ENSMUST00000022223      EVFSMDMFHSCFRKEGIMNPEVGMKYRNLILKPGGSLDGMDMLQNFLQREPNQKAFLMSR
ENST00000242866         EVFSMDMFYSCFKKEGIMNPEVGMKYRNLILKPGGSLDGMDMLHNFLKREPNQKAFLMSR
SINFRUP00000139045      EVYSTDMFFSRFKKEGVLNPKV--------------------------------------
ci0100146871            EVFCFDMFYSRFKKEGIMNQKVGRDYREKILKPGGSIDAEQMLRNFLGRNPNQDAFLQAK
ENST00000028585         RAVASMVWKECFLQD-PFNRAAGERYRREMLAHGGGREPMLMVEGMLQKCPSVDDFVSAL
CG7791-RA               KTIASWIWQTYFEAN-PFNRQAGEKYRAEILAHGGAVPSRKLVANFLQREMTPSVLADSL
                        .. .  ::   *  :  :.  .                                      

ENSMUST00000005057      GLQVEGSE--APAC-----
ENST00000307741         GLQVGGCEPEPQVC-----
SINFRUP00000165285      GLTVE--------------
ENSMUST00000022223      GLNAS--------------
ENST00000242866         GLHAP--------------
SINFRUP00000139045      -------------------
ci0100146871            GLSEKSS------------
ENST00000028585         VSDLDLD---FETFLMDSE
CG7791-RA               ITEIDTDESKIKDLMITRT