CLUSTAL W (1.82) multiple sequence alignment


SINFRUP00000146240      -----------------------------MFRKKKK-KRPEISAPKNFEHRVHTSFDAKR
SINFRUP00000146526      ----------------------------SMFRRRKKTHKPEISAPLNFQHRVHTSFDAAS
ENSMUST00000038071      -----------------------------MFRKKKK-KRPEISAPQNFQHRVHTSFDPKE
ENST00000260404         -----------------------------MFRKKKK-KRPEISAPQNFQHRVHTSFDPKE
ENSMUST00000035264      -----------------------------MFGKKKK--KIEISGPSNFEHRVHTGFDPQE
ENST00000317874         -----------------------------MFGKKKK--KIEISGPSNFEHRVHTGFDPQE
SINFRUP00000150283      -----------------------------MFTKKKK-SRIQISAPSNFEHRVHTDFDEQE
ENST00000321888         PEAPRGVVTCLRALLSHQHQTRPHRVPGTMFGKRKK--RVEISAPSNFEHRVHTGFDQHE
ci0100133563            -------------------------------GKNKR--KPDISGPSNFEHRVHTGFNEDE
CG10295-RC              -----------------------------MSSEEDKPPAPPVRLTSNRGGNERSGGGVGV
                                                     :  ...:     :  . *   . ::. .   

SINFRUP00000146240      GCFVGLPTQWQSLIENLR-RPKPMVDPSRITEVELRPKKTIVRGS-MIGHGDYIAALIND
SINFRUP00000146526      GHFVGLPPQWQSVIDTLQ-RPRPLVDPSRITEIQLH--KTIVRGS-FIGHGAYISHIIAE
ENSMUST00000038071      GKFVGLPPQWQNILDTLR-RPKPVVDPSRITRVQLQPMKTVVRGS-SVPTEGYISGLLND
ENST00000260404         GKFVGLPPQWQNILDTLR-RPKPVVDPSRITRVQLQPMKTVVRGS-AMPVDGYISGLLND
ENSMUST00000035264      QKFTGLPQQWHSLLADTANRPKPMVDPSCITPIQLAPMKTIVRGN-KSCKETSINGLLED
ENST00000317874         QKFTGLPQQWHSLLADTANRPKPMVDPSCITPIQLAPMKTIVRGN-KPCKETSINGLLED
SINFRUP00000150283      QKFVGLPRQWQSLIEDTAKRPKPFIDANVITTVE--PRKTIVRGSSKVGADGSLTWLLDE
ENST00000321888         QKFTGLPRQWQSLIEESARRPKPLVDPACITSIQPGAPKGE-------------------
ci0100133563            GKFIGLPIQWQSIIPDIKNRPKPFIDARHITPVPVEKVNKIITGK------SKTKGPLSN
CG10295-RC              GGGGLGGGGMGDVPPDMRPLPKEPDDSDRKKKTLKSKIKGSKPSHTDSKPNISYPTNFEH
                                   .:       *:   *.   .       :                  :  

SINFRUP00000146240      MSRLSVTSSNSLRKSSPSARKRAQSLGRLG-EVSEGDPYQYESLTQDDEEEEDAA-----
SINFRUP00000146526      MSRLSVISSNSLRRSSQSSRKRAQSMGQLG-ELREDESYEYKTPTG-AAASKTGS-----
ENSMUST00000038071      IQKLSVISSNTLRGRSPTSRRRAQSLGLLGDDQWAADPDMYLQSPQSEHTDPHGL-----
ENST00000260404         IQKLSVISSNTLRGRSPTSRRRAQSLGLLGDEHWATDPDMYLQSPQSERTDPHGL-----
ENSMUST00000035264      FDNISVTRSNSLRKESPPTPDQGAASRIQGHSEENGFITFSQYSSESDTTADYTTEKYRD
ENST00000317874         FDNISVTRSNSLRKESPPTPDQGASSHGPGHAEENGFITFSQYSSESDTTADYTTEKYRE
SINFRUP00000150283      FDNMSVTCSNSLRRGSPPTHP------------------HKDYSS---------------
ENST00000321888         --------PHDVAPNGP-------------------------------------------
ci0100133563            LTAISVTRSNSLRKESPPEIKKLQSRRIPDVVNEDDSSENSSSTTQRPVRSHERNSRRED
CG10295-RC              TVHVGFDAVTGEFTGMPEAWARLLMNSNISKQEQKKNPQAVLDVLKWFDNTTKQRP----
                           : .                                                      

SINFRUP00000146240      --------------QDHWTEKARNIHSETNTPYLGMKKSITLQPNGILPKAKST------
SINFRUP00000146526      --------------SPYWRDSIQRAHSNS----VGPKK------KGALQRTKSS------
ENSMUST00000038071      --------------YLSCNGGTPAGHRQVPWPEPQSPQ---ALPNGMAAKAQSLGPAEFQ
ENST00000260404         --------------YLSCNGGTPAGHKQMPWPEPQSPR---VLPNGLAAKAQSLGPAEFQ
ENSMUST00000035264      RSLYGDDLDLYYKSSHAAKQNGHAMKMKHGDAYYPEMKSLKTDLAGFPVDYHTHLDSLRK
ENST00000317874         KSLYGDDLDPYYRGSHAAKQNGHVMKMKHGEAYYSEVKPLKSDFARFSADYHSHLDSLSK
SINFRUP00000150283      ------------------TEGGRGMSQENGDP----------------------------
ENST00000321888         ------------------SAGGLAIPQ---------------------------------
ci0100133563            --------------DRRHRNNSSHRHEVNSWHPGQGGHQYDTVFDEEKRSSNSRHSSHRK
CG10295-RC              --------------SSKYMTNAITTHSGSSLSRVSSSSPSSTPTDSELHGSNSGGNLIGV
                                                                                    

SINFRUP00000146240      ------------YEVGSHP----------------VSYQNIPVPSYGAYMSGELSSPQER
SINFRUP00000146526      ------------CEVSAPP----------------EATP--TVTTVGHYR--EAQYQQKP
ENSMUST00000038071      GASQRCLQQLGACLQSSPP----------------GTSPPMATGRRGVKVAKHSSEEARP
ENST00000260404         GASQRCLQ-LGACLQSSPP----------------GASPPTGTNRHGMKAAKHGSEEARP
ENSMUST00000035264      SSEYGDLRWDYQRASSSSPLDYSFQLTPSRTAGTSRCSKESLAYSESDWGPSLDDYDRRP
ENST00000317874         PSEYSDLKWEYQRASSSSPLDYSFQFTPSRTAGTSGCSKESLAYSESEWGPSLDDYDRRP
SINFRUP00000150283      ----------IHRHYSNS--------------------------ERHDRNDRRDQPDNRP
ENST00000321888         --------------SSSS------------------------------------------
ci0100133563            HSERTNSGRTHSRDRYEQP---------------HDHHHRSSRESRSQRDIYDRSVEKVY
CG10295-RC              QLGSMTLGPNANNVAVAGQILG-----NHYQQQQQHLLQQQQPLLHQNHNQHHMGISQSH
                                                                                    

SINFRUP00000146240      VIWKKDFQLPRG-MPPSQRPIACFYSPAMTLHQPLGDQTPVSSEARPTLPTYHSGFLPTG
SINFRUP00000146526      NSCHTDARTGK--THSCEQPPDLLSSP----CQPDGLQTNHMVTVICTCADFSSDTLPPR
ENSMUST00000038071      QSCLVGSAIGRPGGEGSPSPKNQESSLKHRLFRSMFLSTPATGAASSSKPVPLPQNKPNS
ENST00000260404         QSCLVGSATGRPGGEGSPSPKTRESSLKRRLFRSMFLSTAATAPPSSSKPGPPPQSKPNS
ENSMUST00000035264      KSSYLHQTSPQPAMRQRSKSGSGLQEPMMPFGASAFKTHPQGHSYNSY--TYPRLSEPTM
ENST00000317874         KSSYLNQTSPQPTMRQRSRSGSGLQEPMMPFGASAFKTHPQGHSYNSY--TYPRLSEPTM
SINFRUP00000150283      KSSYVVRGSPQSPRDKRPLSGPNIRTPNLPVTEGVMKTAQQN-------------TRPFN
ENST00000321888         --------SSRPPTRARGAPSPGVLGPHA--------------------------SEPQL
ci0100133563            SSNHRDRNDRSHRTSDTSVRETSESGPDSRSQSKRTTSHSRRPPDSHDVPDHRQATMPLP
CG10295-RC              SYNFVGHTVSSSTSQHSSANEDDMLGPQHPQQQPPPPPVASRPERTKSIYTRPIEDLQPA
                                                                                    

SINFRUP00000146240      TSSPLVGGILPQRAVRSSASYTL----GLSPNMGVRPTGPEPFLRHSGCPNPPYPREDSP
SINFRUP00000146526      PSPPPNSTSSPLITVR-----------GLLPHSSHPPSSSHIRLRSTSIPG--------I
ENSMUST00000038071      AFRPPQKDSSSNLVAKAQSLPSEQPMGTFSPLTTSDTSSPQKSLRTAPAAG----PLPGR
ENST00000260404         SFRPPQKDNPPSLVAKAQSLPSDQPVGTFSPLTTSDTSSPQKSLRTAPATG----QLPGR
ENSMUST00000035264      CIPKVDYDRAQMVFSPPLSGSDTYPRGPTKLPQSQSKAGYSSGSHQYPSGYHKASLYHHP
ENST00000317874         CIPKVDYDRAQMVLSPPLSGSDTYPRGPAKLPQSQSKSGYSSSSHQYPSGYHKATLYHHP
SINFRUP00000150283      TYPRTDSDGGRSSSSRGSSTSKPPPGHPHAHHTSQPSLTPDSSHHPHTP---------HP
ENST00000321888         APP----------ACTPAAPAVPGPPGP--------------------------------
ci0100133563            SDSREKSRKNKDYYTYSSTVDVRPQNENTVAEHTYQNISNGHRSSEQTNTN-------EK
CG10295-RC              IIPMPVAPATTPATPLQNHRTPGGISAPAASPMMHNNATTTLDKNKNNANLYTP--EPTV
                                                                                    

SINFRUP00000146240      SQPRPSPTGSLATS-PPGMCSPAFRPPQHPSPRPPP-DPPKVTHEQFKAALQMVVDKGDP
SINFRUP00000146526      TKPHP----SQLQD-PPTTC------PSATHLLLPD-GRINVTHDQFKAALQSVVDAGDP
ENSMUST00000038071      SSPAGSPRTRHAQI-STSNLYLPQDPTVAKGALGGE-DTGIVTHEQFKAALRMVVDQGDP
ENST00000260404         SSPAGSPRTWHAQI-STSNLYLPQDPTVAKGALAGE-DTGVVTHEQFKAALRMVVDQGDP
ENSMUST00000035264      SLQTSSQYISTASYLSSLSISSSTYPPPSWGSSSDQ-QPSRVSHEQFRAALQLVVSPGDP
ENST00000317874         SLQSSSQYISTASYLSSLSLSSSTYPPPSWGSSSDQ-QPSRVSHEQFRAALQLVVSPGDP
SINFRUP00000150283      SVPAPRPPVPHGP-------PSSGAPPQ--GRSPQR-EPQRVSHEQFRAALQMVVDPGDP
ENST00000321888         -------------------------------RSPQR-EPQRVSHEQFRAALQLVVDPGDP
ci0100133563            SFRRGQGNVLLVKKPEPLSPGVSVAPPAAQKALGTKRDSHAVTNDQFRAALQMVVCPGDP
CG10295-RC              AQVSAGGPSSQVAGNQIAVPQAAVAPAATPNTRAANAKKKKMSDEEILEKLRTIVSVGDP
                                                                 ::.:::   *: :*  ***

SINFRUP00000146240      RSYLDNFVKIGEGSTGVVCIATEKHSGRQVAVKMMDLRRQQRRELLFNEV----------
SINFRUP00000146526      RTMLENFVKIGEGSTGIVCIAEERESGRQVAVKMMDLRKQQRRELLFNEVGSNPTHHVIE
ENSMUST00000038071      RLLLDSYVKIGEGSTGIVCLAREKHSGRQVAVKMMDLRKQQRRELLFNEV----------
ENST00000260404         RLLLDSYVKIGEGSTGIVCLAREKHSGRQVAVKMMDLRKQQRRELLFNEV----------
ENSMUST00000035264      REYLDNFIKIGEGSTGIVCIATEKHTGKQVAVKKMDLRKQQRRELLFNEV----------
ENST00000317874         REYLANFIKIGEGSTGIVCIATEKHTGKQVAVKKMDLRKQQRRELLFNEV----------
SINFRUP00000150283      RTYLDNYIKIGEGSTGIVCIATVKTTGKLVAVKKMDLRKQQRRELLFNEV----------
ENST00000321888         RSYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEV----------
ci0100133563            RESLENFLKIGEGSTGVVCIANEKGTGRHVAVKKMNVRKQQRRELLFNEV----------
CG10295-RC              NRKYTKMEKIGQGASGTVYTAIESSTGMEVAIKQMNLSQQPKKELIINEI----------
                        .    .  ***:*::* *  *    :*  **:* *:: :* ::**::**:          

SINFRUP00000146240      ----------------VIMRDYQHRNVVEMFKSALVEEELWVIMEYLQGGALTNIVSETR
SINFRUP00000146526      FRGSDQSVMRVCVCQVVIMRDYHHQNVVQMYRSALVGEELWVIMEYLQGGALTHIICQTR
ENSMUST00000038071      ----------------VIMRDYQHLNVVEMYKSYLVGEELWVLMEFLQGGALTDIISQVR
ENST00000260404         ----------------VIMRDYQHFNVVEMYKSYLVGEELWVLMEFLQGGALTDIVSQVR
ENSMUST00000035264      ----------------VIMRDYHHDNVVDMYNSYLVGDELWVVMEFLEGGALTDIVTHTR
ENST00000317874         ----------------VIMRDYHHDNVVDMYSSYLVGDELWVVMEFLEGGALTDIVTHTR
SINFRUP00000150283      ----------------VIMRDYHHENVVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTR
ENST00000321888         ----------------VIMRDYQHENVVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTR
ci0100133563            ----------------VIMRDYHHENIVDMYSSFLVDDELWVVMEYMEGGALTDIVTRTR
CG10295-RC              ----------------LVMRENKHPNVVNYLDSYLVSEELWVVMEYLPGGSLTDVVTETC
                                        ::**: :* *:*:   * ** :****:**:: **:**.:: .. 

SINFRUP00000146240      LNEEQIATVCEAVLQALAYLHSQGVIHRDIKSDSILLTLDGRVKLSDFGFCAQISKDIPK
SINFRUP00000146526      LNEEQIATVCEGVLQALTYLHSQGVIHRDIKSDSILLTLDGRIKLSDFGFCAQISKDVPK
ENSMUST00000038071      LNEEQIATVCEAVLQALAYLHAQGVIHRDIKSDSILLTLDGRVKLSDFGFCAQISKDVPK
ENST00000260404         LNEEQIATVCEAVLQALAYLHAQGVIHRDIKSDSILLTLDGRVKLSDFGFCAQISKDVPK
ENSMUST00000035264      MNEEQIATVCLSVLKALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPK
ENST00000317874         MNEEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPK
SINFRUP00000150283      MNEEQIATVCLSVLKALSVLHKQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVQK
ENST00000321888         MNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPR
ci0100133563            LNEQQIATVCVSVLNALAYLHAQGVIHRDIKSDSILLTKDLTVKLSDFGFCAQISSDVPK
CG10295-RC              MDEGQIAAVCREVLQALEFLHANQVIHRDIKSDNILLGLDGSVKLTDFGFCAQISPEQSK
                        ::* ***:**  **.**  ** : *********.***  *  :**:*******:* :  :

SINFRUP00000146240      RKSLVGTPYWMAPEVISKTPYGTEVDIWSMGIMVVEMVDGEPPYFSDTPVAAMKRLRDEM
SINFRUP00000146526      RKSLVGTPYWMAPEVIAKSPYGPEVDIWSLGIMVVEMVDGEPPYFNQTPISAMKRLRDEA
ENSMUST00000038071      RKSLVGTPYWMAPEVISRSLYATEVDIWSLGIMVIEMVDGEPPYFSDSPVQAMKRLRDSA
ENST00000260404         RKSLVGTPYWMAPEVISRSLYATEVDIWSLGIMVIEMVDGEPPYFSDSPVQAMKRLRDSP
ENSMUST00000035264      RKSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMIDGEPPYFNEPPLQAMRRIRDSL
ENST00000317874         RKSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMIDGEPPYFNEPPLQAMRRIRDSL
SINFRUP00000150283      RKSLVGTPYWMAPELISRLPYGPEVDIWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNL
ENST00000321888         RKSLVGTPYWMAPELISRLPYGPEVDIWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNL
ci0100133563            RKSLVGTPYWMAPEVVSRTPYGPEVDIWSLGIMVMEMVDKEPPYFDEAPLQAMRKIRDMP
CG10295-RC              RTTMVGTPYWMAPEVVTRKQYGPKVDLWSLGIMAIEMVEGEPPYLNENPLKALYLIATNG
                        *.::**********::::  *..:**:**:***.:**:: ****:.: *: *:  :    

SINFRUP00000146240      APT----VRNVSQV----------------------------------------------
SINFRUP00000146526      PPNDFTLTLQVSPVLKDFLGCMLTRDTKQRLTSADLLEHPFLLQADSPGCLMPLVQKHCK
ENSMUST00000038071      PPK-LKNSYKVSPVLRDFLDRMLVREPQERATAQELLDHPFLLQTGLPECLVPLIQLYRK
ENST00000260404         PPK-LKNSHKVSPVLRDFLERMLVRDPQERATAQELLDHPFLLQTGLPECLVPLIQLYRK
ENSMUST00000035264      PPR-VKDLHKVSSMLRGFLDLMLVREPSQRATAQELLGHPFLKLAGPPSCIVPLMRQYRH
ENST00000317874         PPR-VKDLHKVSSVLRGFLDLMLVREPSQRATAQELLGHPFLKLAGPPSCIVPLMRQYRH
SINFRUP00000150283      PPK-LKNLHKVSPLLKGFLDRMLVRDPAQRAVASEILKHPFLTKAGPPSCIVPLMRQNRM
ENST00000321888         PPR-LKNLHKVSPSLKGFLDRLLVRDPAQRATAAELLKHPFLAKAGPPASIVPLMRQNRT
ci0100133563            PPK-LKNAHKASPLLKGFLDQVLVRDPSTRSTALELLQHPFLRKSSSHKSIGPI------
CG10295-RC              KPE-IKEKDKLSSAFQDFLDQCLEVEVDRRASALDLLKHPFLKLARPLASLTPLIMAAKE
                         *       : *                                                

SINFRUP00000146240      -----
SINFRUP00000146526      RMSLC
ENSMUST00000038071      QTSTC
ENST00000260404         QTSTC
ENSMUST00000035264      H----
ENST00000317874         H----
SINFRUP00000150283      R----
ENST00000321888         R----
ci0100133563            -----
CG10295-RC              ATKGN