CLUSTAL W (1.82) multiple sequence alignment


ENST00000263124         ---------------ECILSGIMSVNGKKVLHMDRNPYYGGESASITPLEDLYKRFKIPG
ENSMUST00000002026      ---------------ECILSGIMSVNGKKVLHMDQNPYYGGESASITPLEDLYKRFKLPG
ENSMUST00000057440      ---EYNVMVLGTGLTECILSGIMSINGKKVLYMGQNSYYGGESASITPLEDLYKRCKLPE
ENST00000218250         ---------------ECILSGIMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFQLLE
ENSMUST00000015435      MDEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFQILE
SINFRUP00000159199      ---------------ECILSGIMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFSLPD
SINFRUP00000148906      ---------------ECILSGIMSVKGKKVLHMDRNNFYGAESASITPLDELYKRFSLPG
CG4422-RA               MNEEYDAIVLGTGLKECILSGMLSVSGKKVLHIDRNKYYGGESASITPLEELFQRYGLE-
                                       ******::*:.*****::.:* :**.**:*****::*::*  :  

ENST00000263124         SPPESMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVTEGSFVYKGGKIYKVP
ENSMUST00000002026      QPPASMGRGRDWNVDLIPKFLMANGQLVKMLLFTEVTRYMDFKVIEGSFVYKGGKIYKVP
ENSMUST00000057440      QRPASMGRGRDWNVNLIPKFLMANGQLVKMLLFTEVTRYMDFRVIEGSFVYKGGKIYKVP
ENST00000218250         GPPESMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVVEGSFVYKGGKIYKVP
ENSMUST00000015435      GPPESMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVVEGSFVYKGGKIYKVP
SINFRUP00000159199      SPPESMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVVEGSFVYKGGKIYKVP
SINFRUP00000148906      KPPESMGKGRDWNVDLIPKFLMSNGQLARMLLITSVTRYLDFKVVMGSFVYKNGNIYKVP
CG4422-RA               PPGERFGRGRDWNVDLIPKFLMANGQLVKLLIHTGVTRYLEFKSIEGSYVYKGGKIAKVP
                             :*:******:*******:****.::*: * ****::*:   **:***.*:* ***

ENST00000263124         STEAEALASSLMGLFEKRRFRKFLVYVANFDEKDPRTFEGIDPKKTTMRDVYKKFDLGQD
ENSMUST00000002026      STEAEALASSLMGLFEKRRFRKFLVYVANFDEKDPRTFEGVDPKKTSMRDVYKKFDLGQD
ENSMUST00000057440      STEAEALACSLMGLLEKRCFGKFLVYVVNFDEKDPRTFEGVDPKKTSMRDVYKKFDLGQD
ENST00000218250         STETEALASNLMGMFEKRRFRKFLVFVANFDENDPKTFEGVDPQTTSMRDVYRKFDLGQD
ENSMUST00000015435      STETEALASNLMGMFEKRRFRKFLVFVANFDENDPKTFEGVDPQNTSMRDVYRKFDLGQD
SINFRUP00000159199      STETEALASNLMGMFEKRRFRKFLVFVANFDENDPKTFEGVDPKTTKMRDVYKKFDLGQD
SINFRUP00000148906      STETEALATKLLGLFEKRRFKKFLGFVANIDVNDPKTLDGVDPQKTTMRELYSKFSLGPD
CG4422-RA               VDQKEALASDLMGMFEKRRFRNFLIYVQDFREDDPKTWKDFDPTKANMQGLYDKFGLDKN
                          : **** .*:*::*** * :** :* ::  .**:* ...** .:.*: :* **.*. :

ENST00000263124         VIDFTGHALALYRTDDYLDQPCYETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFAR
ENSMUST00000002026      VIDFTGHSLALYRTDDYLDQPCCETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFAR
ENSMUST00000057440      VIDFTGHSLALYRTGGYLDQPCCETINRIKRCSESLARYGKSPYLYPLNGLGELLQGFAR
ENST00000218250         VIDFTGHALALYRTDDYLDQPCLETVNRIKLYSESLARYGKSPYLYPLYGLGELPQGFAR
ENSMUST00000015435      VIDFTGHALALYRTDDYLDQPCLETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFAR
SINFRUP00000159199      VIDFTGHALALYRTDDYLDVPCLETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFAR
SINFRUP00000148906      VVDFTGHALALYGTDDYIDRPCIETINRIKLYSESLARYGQSPYLYPMYGLGELPQGFAR
CG4422-RA               TQDFTGHALALFRDDEYLNEPAVNTIRRIKLYSDSLARYGKSPYLYPMYGLGELPQGFAR
                        . *****:***:  . *:: *. :*:.***  *:******:******: ***** *****

ENST00000263124         LSAIYGGTYMLNKPIEEIIV-QNGKVIGVKSEGEIARCKQLICDPSYVKDRVEKVGQVIR
ENSMUST00000002026      LSAIYGGTYMLNKPIEEIIV-QNGKVVGVKSEGEIARCKQLICDPSYVKDRVEKVGQVIR
ENSMUST00000057440      LSAIYGGTYMLNKPVEEIIV-QNGKVVSVKLKERLLAVNS-SSVISYVKDRVEKVGQVVR
ENST00000218250         LSAIYGGTYMLNKPVDDIIM-ENGKVVGVKSEGEVARCKQLICDPSYIPDRVRKAGQVIR
ENSMUST00000015435      LSAIYGGTYMLNKPVDDIIM-ENGKVVGVKSEGEVARCKQLICDPSYIPDRVQKAGQVIR
SINFRUP00000159199      LSAIYGGTYMLNKPVDEIVM-EGGHVVGVKSEGEVARCKQLICDPSYVPDRVRKAGQVIR
SINFRUP00000148906      LSAIYGGTYMLNKPIEEIIM-EDGKVVGVKSDGEIARCKQLICDPSYVPERVTKVGQVIR
CG4422-RA               LSAIYGGTYMLDKPIDEIVLGEGGKVVGVRSGEEVAKCKQVYCDPSYVPEKVRKRGKVIR
                        ***********:**:::*:: :.*:*:.*:   .:   :.: .  **: ::* * *:*:*

ENST00000263124         VICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISFAHNVAAQGKYIAIVSTTVET
ENSMUST00000002026      VICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISFAHNVAAQGKYIAIVSTTVET
ENSMUST00000057440      VICILSHPIKNTNDAKSCQIVIPQKQVNRKSDIYVFMISFAHNVTAKGKYIAIVSTTLET
ENST00000218250         IICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISYAHNVAAQGKYIAIASTTVET
ENSMUST00000015435      IICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISYAHNVAAQGKYIAIASTTVET
SINFRUP00000159199      VICILSHPIKNTNDANSCQIIIPQNQVNRNSDIYVCMISYAHNVAAQGKYIAIVSTTVET
SINFRUP00000148906      VICILSHPIANTNNSNSCQIIIPQNQVNRKHDIYVCMISFAHNVAAEGKYIAIASTSVET
CG4422-RA               CICILDHPVASTKDGLSTQIIIPQKQVGRKSDIYVSLVSSTHQVAAKGWFVGMVSTTVET
                         ****.**: .*::. * **:***:**.*: **** ::* :*:*:*:* ::.:.**::**

ENST00000263124         KEPEKEIRPALELLEPIEQKFVSISDLLVPKDLGTESQIFISRTYDATTHFETTCDDIKN
ENSMUST00000002026      KEPEKEIRPALELLEPIEQKFVSISDLFVPKDLGTDSQIFISRAYDATTHFETTCDDIKD
ENSMUST00000057440      KEPEKEIRLALELLEPIEQEFVSISDLFVPKD----------------------------
ENST00000218250         TDPEKEVEPALELLEPIDQKFVAISDLYEPIDDGCESQVFCSCSYDATTHFETTCNDIKD
ENSMUST00000015435      AEPEKEVEPALELLEPIDQKFVAISDLYEPIDDGSESQVFCSCSYDATTHFETTCNDIKD
SINFRUP00000159199      SEPEAEIQPALELLEPIDQKFVAISDLYEPTDDGSESQVFASSSYDATTHFETTCNDIKD
SINFRUP00000148906      NDPEQEIKPALDLLMPIDQKFVSIADQYEPTDPGTENQV---------------------
CG4422-RA               ENPEVEIKPGLDLLEPIAQKFVTISDYLEPIDDGSESQIFISESYDATTHFETTCLDVLN
                         :** *:. .*:** ** *:**:*:*   * *      :                     

ENST00000263124         IYKRMTGSEFDFEEMKRKKNDIYGED--
ENSMUST00000002026      IYKRMTGSEFDFEEMKRKKNDIYGED--
ENSMUST00000057440      ----------------------------
ENST00000218250         IYKRMAGTAFDFENMKRKQNDVFGEAEQ
ENSMUST00000015435      IYKRMAGSAFDFENMKRKQNDVFGEADQ
SINFRUP00000159199      IYKRMTGSDFDFENMKRKQNDVFGEDEQ
SINFRUP00000148906      ----------------------------
CG4422-RA               IFKRGTGETFDFSKIKHELGDEEQ----