CLUSTAL W (1.82) multiple sequence alignment


ENST00000326662         MALDGIRMPDGCYADGTWELSVHVTDLN----RDVTLRVTGEVHIGGVMLKLVEKLDVKK
ENSMUST00000045905      ----GIRMPDGCYADGTWELSVHVTDLN----RDVTLRVTGEVHIGGVMLKLVEKLDVKK
SINFRUP00000149485      MALDGIRMPDGCYADGTWELKMHVTDLN----RDVSLRVTGEIHVGGVMLKLVEKLDVKK
ENSMUST00000038280      ----MLSSGD--LTSASWELVVRVDHANGEQQTEITLRVSGDLHIGGVMLKLVEQMNIAQ
ENST00000245975         ----MLSSTD--FTFASWELVVRVDHPNEEQQKDVTLRVSGDLHVGGVMLKLVEQINISQ
SINFRUP00000127575      ----MVTTPD--YEEMSWELSVQIDQKSGDEAMKFKLRVKGDLHIGGLMLKLVEKIKAPQ
ENSMUST00000040772      --MAGMKTASGDYIDSSWELRVFVGEED-PEAQSVTLRVTGESHIGGVLLKIVEEINRKQ
CG14991-RA              ----MIHVGEN-----TWNLRILITDLQ----VEKTLRVKGDQHIGGVMLNLVDP-ELPK
                        : :  :   .      :*:* : : . .     . .***.*: *:**::*::*: :.  :

ENST00000326662         DWSDHALWWEKKRTWLLKTHWTLDKYGIQADAKLQFTPQHKLLRLQLPNMKYVKVKVNFS
ENSMUST00000045905      DWSDHALWWEKKRTWLLKTHWTLDKCGIQADAKLQFTPQHKLLRLQLPNMKYVKVKVNFS
SINFRUP00000149485      DWSDHALWWEKKKTWLLKTHWTLDKYGIQADARLLFTPQHKLLRLQLPNMKHMKVKVNFS
ENSMUST00000038280      DWSDYALWWEQKRCWLLKTHWTLDKCGVQADANLLFTPQHKMLRLRLPNAKTVRLRVSFS
ENST00000245975         DWSDFALWWEQKHCWLLKTHWTLDKYGVQADAKLLFTPQHKMLRLRLPNLKMVRLRVSFS
SINFRUP00000127575      DWSDHALWWEQRKCWLLKTHWTLDKYGIQADADLRYTPQHKPLLVQLPNMKTILLTVSFS
ENSMUST00000040772      DWSDHAIWWEQKRQWLLQTHWTLDKYGILADARLFFGPQHRPVILRLPNRRVLRLRASFS
CG14991-RA              DWSDHALWWPAKNIWLTRTRSTLDQAGVQSDSFLHFTPMHKTLRVQMPDLRYLDYRVNFS
                        ****.*:**  :. ** :*: ***: *: :*: * : * *: : :::*: : :   ..**

ENST00000326662         DRVFKAVSDICKTFNIRHPEELSLLKKPRDPTKKKKKKLDDQSEDEALELEGPLITP---
ENSMUST00000045905      DRVFKAVSDICKTFNIRHPEELSLLKKPRDPTKKKKKKLDDQSEDEALELEGPLIMP---
SINFRUP00000149485      DRVFKAVSDICKTFNIRHPEELSLLRKPRDP-KKKKKKLEEVEED-DLELEGPLLTP---
ENSMUST00000038280      AVVFKAVADICKVLNIRRPEELSLLKPSSDYCKKKKKKEKNSKEPVIEDILNLESSS---
ENST00000245975         AVVFKAVSDICKILNIRRSEELSLLKPSGDYFKKKKKKDKNNKEPIIEDILNLESSP---
SINFRUP00000127575      SVVFKTVADICRILNLRRSEELSLLKPPDDASNKKKKKDKNAR----EDIWDIDLFS---
ENSMUST00000040772      KPLFQTVAAICRLLSIRHPEELSLLRAPEKKEKKKKEKEPEEE---VHDLTKVVLAG---
CG14991-RA              AKTFGAVVSLCKDLDIRYPEELSFCKPLEPEHLKKNFSKLPQRKIPVAEANGIAYVQPAL
                           * :*  :*: :.:* .****: :       **: .          :           

ENST00000326662         GSGSIYSSPGLYSKTMTPTYDAHDGSPLSPTSAWFGDSALSEGNPGI-------------
ENSMUST00000045905      GSGSIYSSPGLYSKTMTPTYDAHDGSPLSPTSAWFGDSALSEGNPGI-------------
SINFRUP00000149485      GSGSIYSSPGLYSKTMTPTYDSRDGSPLSPTTAWFGDSPLSEGNPSI-------------
ENSMUST00000038280      TSSGSPVSPGLYSKTMTPTYDPINGTPALSTMTWFGDSPLTEQNCSV-------------
ENST00000245975         TASGSSVSPGLYSKTMTPIYDPINGTPASSTMTWFSDSPLTEQNCSI-------------
SINFRUP00000127575      GTSGAAGTQRKAKCSITNISQQTFAAFLKRPFYFVTEYNLNSSEC---------------
ENSMUST00000040772      GVAP---------------------TLFRGMPAHFSDSAQTEACYHM-------------
CG14991-RA              DTNSFVPITGAYNGSNGSLDRSHNGNLLCAPASPYTRRAATAPGTPISSPTGTWKHNSTG
                                                                .     :             

ENST00000326662         ----------------LAVSQPITSPEILAKMFKPQALLDKAKINQGWLDSSRSLMEQDV
ENSMUST00000045905      ----------------LAVSQPVTSPEILAKMFKPQALLDKAKTNQGWLDSSRSLMEQDV
SINFRUP00000149485      ----------------LAVSQPISSPDILVKLYKPQSLLDKAKINQGWLDSSRSLMEQDV
ENSMUST00000038280      ----------------LAFSQPPPSPDVLADMFQPRSLVDKAKMNAGWLDSSRSLMEQSI
ENST00000245975         ----------------LAFSQPPQSPEALADMYQPRSLVDKAKLNAGWLDSSRSLMEQGI
SINFRUP00000127575      --------------------LPNLPPAELAKIYQPLSLVDKANNFSGWLDSSRSLMEQDV
ENSMUST00000040772      ----------------LSRPQPAPDPLLLQRLPRPSSLPDKTQLHSRWLDSSRCLMQQGI
CG14991-RA              YASYDSNSSFGDLQENLAMSPRSPSPDVRARLVRPKSRVEKARLNVGWLDSSLSIMEQGV
                                        :        *     : :* :  :*:.    ***** .:*:*.:

ENST00000326662         KENEALLLRFKYYSFFDLNPKYDAIRINQLYEQAKWAILLEEIECTEEEMMMFAALQYHI
ENSMUST00000045905      KENEALLLRFKYYSFFDLNPKYDAIRINQLYEQAKWALLLEEIECTEEEMMMFAALQYHI
SINFRUP00000149485      KENEVLLLRFKYHSFFDLNPKYDAIRVNQLYEQAKWAILLEEIECTEEEMMMFAALQYHI
ENSMUST00000038280      QEDEQLQLRFKYYTFFDLNPKYDAVRINQLYEQARWAVLLEEIDCTEEEMLIFAALQYHI
ENST00000245975         QEDEQLLLRFKYYSFFDLNPKYDAVRINQLYEQARWAILLEEIDCTEEEMLIFAALQYHI
SINFRUP00000127575      QDEDKLLLRFKYHVFFDLNPKYDAVRITQLYEQARWNILLEEIDCTEEEMLMFASLQYHI
ENSMUST00000040772      KAGDVLWLRFKYYSFFDLDPKTDPVRLTQLYEQARWDLLTEEIDCTEEEMMVFAALQYHI
CG14991-RA              REYDTLCLRFKYFTFFDLNPKYDQVRINQLYEQAKWSILNEELEPTEEETLMFAALQFQV
                        :  : * *****. ****:** * :*:.******:* :* **:: **** ::**:**:::

ENST00000326662         NKLSIMTSENHLNNSDK------EVDEVDAALSDLEITLEGGKTSTILGDITSIPELADY
ENSMUST00000045905      NKLSIMTSENHLNNSDK------EVDEVDAALSDLEITLEGGKTSTILGDITSIPELADY
SINFRUP00000149485      NKLSIMSSDNHMNNSEK------EVDEVDAALSDLEITLEGGKTSNTLGDITSIPELADY
ENSMUST00000038280      SKLSQC-AEIQDFATKS------EVDEVEAALSSLEVTLEGGKADNTLEDITDIPKLADY
ENST00000245975         SKLSLS-AETQDFAGES------EVDEIEAALSNLEVTLEGGKADSLLEDITDIPKLADN
SINFRUP00000127575      CKLTLS-NEPLDHSKEP------EIDEVEAALSNLEVTLEGGHTDKILEDITDIPELADT
ENSMUST00000040772      NKLTLSGDVGELASGDL------GLDDLDAALNNLEVKLKGSAPSDMLDSLTTIPELKDH
CG14991-RA              NHQTDLHPPGIDSGIDTSSQETGGEDDIDSALNELQITLEGPGGGKDQGNITRIPELSDY
                         : :           .         *::::**..*::.*:*   .    .:* **:* * 

ENST00000326662         IKVFKPKKLTLKGYKQYWCTFKDTSISCYKSKEESS-GTPAHQMNLRGCEVTPDVNISGQ
ENSMUST00000045905      IKVFKPKKLTLKGYKQYWCTFKDTSISCYKSREESS-GTPAHQLNLRGCEVTPDVNISGQ
SINFRUP00000149485      VKVFKPKKLTLKGYKQYWCTFKDITISCYKSKEEAH-GTPAHQMNLXGXEVTPDVNISGQ
ENSMUST00000038280      LKLFRPKKLMLKACKQYWFVFKDTSIAYFKNKELEQ-GEPIEKLNLRGCEIVPDVNVSGR
ENST00000245975         LKLFRPKKLLPKAFKQYWFIFKDTSIAYFKNKELEQ-GEPLEKLNLRGCEVVPDVNVAGR
SINFRUP00000127575      LRLFRPKRLTLRPYKEYWFVFKDTTISYFKNKEASY-GEPIEQFHLRGCEVVPDVNVTDK
ENSMUST00000040772      LRIFRPRKLTLKGYRQYWVVFKDTTLSYYKSQDEAP-GDPTQQLNLKGCEVVPDVNVSGQ
CG14991-RA              LKFLKPQRFTLKGYKRYFFTYRDLHLHLYKSQDESRRGAPTISINLKGCEVTPDVNLAQG
                        ::.::*:::  :  :.*:  ::*  :  :*.::    * *  .::* * *:.****::  

ENST00000326662         KFNIKLLIP--VAEGMN-EIWLRCDNEKQYAHWMAACRLASKGKTMADSSYNLEVQNILS
ENSMUST00000045905      KFNIKLLIP--VAEGMN-EIWLRCDNEKQYAHWMAACRLASKGKTMADSSYNLEVQNILS
SINFRUP00000149485      KFNIKLLIP--VADGMN-EIWLRCDTEKQYAQWMAACRLASKGKTMADSSYNLEVQNILS
ENSMUST00000038280      KFGIKLLIP--VADGMN-EVYLRCDHEDQYARWMAACILASKGKTMADSSYQPEVISILS
ENST00000245975         KFGIKLLIP--VADGMN-EMYLRCDHENQYAQWMAACMLASKGKTMADSSYQPEVLNILS
SINFRUP00000127575      KFGIKLLLP--VADGMN-EIYIRCNNETQYAKWKAACILASKGKTMAYSSYKSEVRNIQS
ENSMUST00000040772      KFCIKLLVP--SPEGMS-EIYLRCQDEQQYAQWMAACRLASKGRTMADSSYASEVQAILA
CG14991-RA              KFAIRLEVPSEIRNGPNSEVWVRCDNEEQYAKWMAACRLAAKGRSLADSSYDSEVSSIRS
                        ** *:* :*    :* . *:::**: * ***:* *** **:**:::* ***  **  * :

ENST00000326662         FLKMQHLNPDP------QLIPEQITTDITPECLVSPRYLKKYKNKQITARILEAHQNVAQ
ENSMUST00000045905      FLKMQHLNPDP------QLIPDQITTDVNPECLVSPRYLKKYKSKQITARILEAHQNVAQ
SINFRUP00000149485      FLKMQHMNPDP------QFI-EAISTDINPECLVSPRYLKKYRNKQISARILEAHQNVAQ
ENSMUST00000038280      FLKMKNRNSSP------LVASSLENMDMNPECLVSPCCAKKHKSKQLAARILEAHHNVAQ
ENST00000245975         FLRMKNRNSAS------QVASSLENMDMNPECFVSPRCAKRHKSKQLAARILEAHQNVAQ
SINFRUP00000127575      FLQMKSLAPPPG-----QATPDLDTMEMNAECFVSPRYAKKHKTKQLTTRILEAHQNIAN
ENSMUST00000040772      FLSLQRAGGSNGGSGNKPQGPEAPAEGLNPYGLVAPRFQRKFKAKQLTPRILEAHQNVAQ
CG14991-RA              LLQMQKPAQGAP--------LTVNPRSVEPMDYLSPKMMRKLSSK-AVQRILEAHANVRQ
                        :* ::                      : .   ::*   ::   *    ****** *: :

ENST00000326662         MSLIEAKMRFIQAWQSLPEFGITHFIARFQGGKKEELIGIAYNRLIRMDASTGDAIKTWR
ENSMUST00000045905      MSLIEAKMRFIQAWQSLPEFGITHFIARFQGGKREELIGIAYNRLIRMDASTGDAIKTWR
SINFRUP00000149485      MSLIEAKMRFIQAWQSLPEFGITHFLAKFQGGKREELIGITYNRLIRMDAGTGDAIKTWR
ENSMUST00000038280      MPLVEAKLQFIQAWQSLPEFGLTYYLVRFKGSKKDDILGVAYNRLIRIDAVTGIPVTTWR
ENST00000245975         MPLVEAKLRFIQAWQSLPEFGLTYYLVRFKGSKKDDILGVSYNRLIKIDAATGIPVTTWR
SINFRUP00000127575      LSLMEAKMRFIQAWQSLPEFGIKYYIVRFKGSKKDEILGISYNRMFRIDMSTGLPVTTWR
ENSMUST00000040772      LSLTEAQLRFIQAWQSLPDFGISYVMVRFKGSRKDEILGIANNRLIRIDLAVGDVVKTWR
CG14991-RA              LSLMDAKMKYIQAWQSLPDFGVTLFIIKFDGHKKEELLGVANNRIMRMDLNTGDHIKTWR
                        :.* :*::::********:**:.  : :*.* ::::::*:: **::::*  .*  :.***

ENST00000326662         FSNMKQWNVNWEIKMVTVEFADEVRLSFICTEVDCKVVHEFIGGYIFLSTRAKDQNESLD
ENSMUST00000045905      FSNMKQWNVNWEIKMVTVEFADEVRLSFICTEVDCKVVHEFIGGYIFLSTRAKDQNESLD
SINFRUP00000149485      FSNMKQWNVNWEIKMVTVEFADEPSLSFICAEVDCKV-----------------------
ENSMUST00000038280      FANMKQWNVNWEIRQVAIEFDQNVSIAFTCLSADCKIVHEYIGGYIFLSTRSKDQNETLD
ENST00000245975         FTNIKQWNVNWETRQVVIEFDQNVFTAFTCLSADCKIVHEYIGGYIFLSTRSKDQNETLD
SINFRUP00000127575      FANIKQWNVNWR-EQVAIEFDQNVSIAFCCLSCDCKVVHEFIGGYIFLSTRSKDQNETLD
ENSMUST00000040772      FSNMRQWNVNWDIRQVAIEFDEHINVAFSCVSASCRIVHEYIGGYIFLSTRERARGEELD
CG14991-RA              YNTMKAWNVNWGIKCMMIQLQDE-NIVFSVQSADCKVVHEFIGGYIFMSMRSKENNQTLN
                        : .:: *****  . : ::: :.    *   . .*::                       

ENST00000326662         EEMFYKLTSGWV--
ENSMUST00000045905      EEMFYKLTSG----
SINFRUP00000149485      --------------
ENSMUST00000038280      EDLFHKLTGGQD--
ENST00000245975         EDLFHKLTGGQD--
SINFRUP00000127575      EELFHKLTGGQD--
ENSMUST00000040772      EDLFLQLTGGHEAF
CG14991-RA              EEMFHKLTGGWS--