CLUSTAL W (1.82) multiple sequence alignment


ENSMUST00000045469      -------------------MELEVPDEAESAEAGAVTAEAAWSAESGAAAGMTQKKAGLA
ENST00000262964         AAVAARVPLGRPRRRPRAAMELEVPDEAESAEAGAVPSEAAWAAESGAAAGLAQKKAAPT
SINFRUP00000160519      ------------------------------------------------------------
ENSMUST00000025800      ------------------------------------------------------------
ENST00000327329         ------------------------------------------------------------
SINFRUP00000158440      ------------------------------------------------------------
ENST00000271663         --------------------------MASASSGPSSSVGFSSFDPAVPSCTLSSASGIKR
ENST00000316494         --------------------------MASASSGPLSSVGFS-VDPAVPSCTSSSASGIKS
ENST00000309390         --------------------------MASASSQPSLAVGFSSFDPGAPSCTASSASGILS
SINFRUP00000160931      -------------------------------QGPSTSLSQN-------------------
ci0100147804            --------------------------MATKEEPTSNPVNPG-----------KPVDDPSK
CG3682-RA               ------------------MASGDGDTINTIDMDSSSASQAKLAEPSNASTDHVGNSSPDL
                                                                                    

ENSMUST00000045469      EAPLVTGQPGPGHGKKLGHRGVD-ASGETTYKKTTSSTLKGAIQLGIGYTVGNLSSKPER
ENST00000262964         EVLSMTAQPGPGHGKKLGHRGVD-ASGETTYKKTTSSTLKGAIQLGIGYTVGHLSSKPER
SINFRUP00000160519      ----------PGQGKKIGHRGVD-ASGETTYKKTTSSALKGAIQLGIGYTVGNLSSKPER
ENSMUST00000025800      ---------MSSTAENGDAVPGK-QNEEKTYKKTASSAIKGAIQLGIGYTVGNLTSKPER
ENST00000327329         ---------MSSAAENGEAAPGK-QNEEKTYKKTASSAIKGAIQLGIGYTVGNLTSKPER
SINFRUP00000158440      -----------------------------SYQLTAS-AIKGAIQLGIGYVVGNLNSKPDR
ENST00000271663         PMASEVPYASGMPIKKIGHRSVD-SSGETTYKKTTSSALKGAIQLGITHTVGSLSTKPER
ENST00000316494         PMASEVPYASGMPIKKIGHRSVD-SSG-----GTTSSALKGAIQLGITHTVGSLSTKPES
ENST00000309390         PTASEVPYASGMPIKKTGHRGVD-SSGETTYKKTTSTALKGAIQLGITYTVGSLSTKPER
SINFRUP00000160931      ------------AKKTIGHRGID-PTGETTYKKTTSSALKGAIQLGITHTVGSLSQKPER
ci0100147804            DIVPETAVVTKVTQKKIGHRRVDASTGQTTYKKTPSSALSGSIQLAISHTVAGLSSKPER
CG3682-RA               GNRPNRASSKADKERKIGHRRVG-EGGEITYKKIQTSQIMGSIQLGIQHTVGSLASKPKR
                                                           :  : *:***.* :.*. *  **. 

ENSMUST00000045469      DVLMQDFYVVESIFFPSEGSNLTPAHHFQDFRFKTYAPVAFRYFRELFGIRPDDYLYSLC
ENST00000262964         DVLMQDFYVVESIFFPSEGSNLTPAHHFQDFRFKTYAPVAFRYFRELFGIRPDDYLYSLC
SINFRUP00000160519      DVLMQDFYVVESIFFPSEGSNLTPAHHFPDFRFKTYAPVAFRYFRELFGIRPDDYLYSLC
ENSMUST00000025800      DVLMQDFYVVESVFLPSEGSNLTPAHHYPDFRFKTYAPLAFRYFRELFGIKPDDYLYSIC
ENST00000327329         DVLMQDFYVVESVFLPSEGSNLTPAHHYPDFRFKTYAPLAFRYFRELFGIKPDDYLYSIC
SINFRUP00000158440      DVLMQDFSVVESVFLPNEGSNLTPAHHFPDFRLKSYAPLAFRYFRELFGIKPDDYLYSIC
ENST00000271663         DVLMQDFYVVESIFFPSEGSNLTPAHHYNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLC
ENST00000316494         DVLMQDFHMVESIFFPSEGSNLTPAHHYNAFRFKTYAPVAFRYFWELFGIRPDDYLYSLC
ENST00000309390         DVLMQDFYVVESIFFPSEGSNLTPAHHYNAFRFKTYAPVAFRYFRELFGIPPDDYLCSLC
SINFRUP00000160931      DVLLQDFEVVESIFFPSAGSYLTPAHHYGDFRFKTYAPMAFRYFREMFGIRPDDYMYSLC
ci0100147804            DVLMQDFQVVETIVFPSEGSNLTPAHHFGEFTFRTYAPTAFRYFRDLFGIRPDDYMLSIS
CG3682-RA               DLLMMDFWEIESITFPPEGSSLTPAHHYSEFRYKIYAPIAFRYFRDLFGIQPDDFMMSMC
                        *:*: **  :*:: :*  ** ******:  *  : *** ***** ::*** ***:: *:.

ENSMUST00000045469      NEPLIELSNPGASGSVFYVTSDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKF
ENST00000262964         NEPLIELSNPGASGSLFYVTSDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKF
SINFRUP00000160519      NEPLIELSNPGASGSVFYVTKDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKF
ENSMUST00000025800      SEPLIELSNPGASGSLFFLTSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKF
ENST00000327329         SEPLIELSNPGASGSLFFVTSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKF
SINFRUP00000158440      NEPLIELSNPGASSSWFYLTSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKF
ENST00000271663         SEPLIELCSSGASGSLFYVSSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKF
ENST00000316494         SEPLIELCSSGASGSLFYVSSDDEFIVKTVRHKEAEFLQKLLPGYYINLNQNPRTLLPKF
ENST00000309390         SEPLIELCSSGASGSLFYVSSDDELIIKTLQHKEAEFLQKLLPGYYLNLSQNPRTLLPKF
SINFRUP00000160931      NEGLIELSNSGASGSLFYLSSDDEFIIKTVQHKEAEFLQKLLPGYFMNLNQNKRTLLPKF
ci0100147804            RLPLRELSNPGASGSLFFVTHDDEFIIKTVQHKEAEFLQKLLPGYYMNLVQNPRTLLPKF
CG3682-RA               TSPLRELSNPGASGSIFYLTTDDEFIIKTVQHKEGEFLQKLLPGYYMNLNQNPRTLLPKF
                           * **...***.* *::: ***:*:**: ***.**********::** ** *******

ENSMUST00000045469      YGLYCVQSG-GKNIRVVVMNNVLPRVVKMHLKFDLKGSTYKRRASKKEKEKSLPTYKDLD
ENST00000262964         YGLYCVQSG-GKNIRVVVMNNILPRVVKMHLKFDLKGSTYKRRASKKEKEKSFPTYKDLD
SINFRUP00000160519      FGLYCVQSG-GKNIRMVVMNNVLPRVVRMHLKYDLKGSTYKRRASKKEREKARPTFKDLD
ENSMUST00000025800      YGLYCMQSG-GINIRIVVMNNVLPRAMRMHLTYDLKGSTYKRRASRKEREKPNPTFKDLD
ENST00000327329         YGLYCMQSG-GINIRIVVMNNVLPRSMRMHFTYDLKGSTYKRRASRKEREKSNPTFKDLD
SINFRUP00000158440      YGLYCIQCS-GITIRVVVMNNILPRAMEMHYKYDLKGSSYKRCASRKERAKSSPTFKDLD
ENST00000271663         YGLYCVQAG-GKNIRIVVMNNLLPRSVKMHIKYDLKGSTYKRRASQKEREKPLPTFKDLD
ENST00000316494         YGLYCVQTG-GKNIRIVVMNNLLPRSVKMHIKYDLKGSTYRRRASQKEREKPLPTFKDLD
ENST00000309390         FGLYCVQTG-GKNIRIVVMNNLLPRSVKMHIKYDLKGSTYKRRASQKEREKPLPTFKDLD
SINFRUP00000160931      YGLYCVQAA-GKNIRIVVMNNLLPSSVRMHRKFDLKGSTYKRRVSAKEKAKAVPTYKDLD
ci0100147804            YGLYNVQSG-GKNIRMVVMNNLLPSVIKMHLKYDLKGSTYKRKASKHERAKKNPTYKDLD
CG3682-RA               FGLYCLQTSNAKNIRLVVMNNLLPSSVKMHLKYDLKGSTFKRKANKAERAKKSPTYKDLD
                        :*** :* . . .**:*****:**  :.** .:*****:::* ..  *: *  **:****

ENSMUST00000045469      FMQDMPEGLLLDSDTFGALVKTLQRDCLVLESFKIMDYSLLLGVHNIDQQERE--RQAEG
ENST00000262964         FMQDMPEGLLLDADTFSALVKTLQRDCLVLESFKIMDYSLLLGVHNIDQHERE--RQAQG
SINFRUP00000160519      FMQDLQDGLMLDQDTYNALAKTLQRDCLVLESFKIMDYSLLLGVHNMDQAERE--RQMEG
ENSMUST00000025800      FLQDMHEGLYFDTETYNALMKTLQRDCRVLESFKIMDYSLLLGIHILDHSLKD--KEEEP
ENST00000327329         FLQDMHEGLYFDTETYNALMKTLQRDCRVLESFKIMDYSLLLGIHFLDHSLKE--KEEET
SINFRUP00000158440      F-KDMHEGLNLDSETYNALMKTLQRDCRVLESFKIMDYSLLLGIHVLDHKPLS--RGSR-
ENST00000271663         FLQDIPDGLFLDADMYNALCKTLQRDCLVLQSFKIMDYSLLMSIHNIDHAQREPLSSET-
ENST00000316494         FLQDIPDGLFLDADVHNALCKTLQRDCLVLQSFKIMDYSLLMSIHNIDHAQREPLSSET-
ENST00000309390         FLQDIPDGLFLDADTYNALCKTLQRDCLVLQSFKIMDYSLWLSIHNIDHAQREPLSSDTL
SINFRUP00000160931      FMQDIPEGLLLELNKYNAVCKTIHRDCLLLQSFKIMDYSLLVGIHNLDQACREQANRESA
ci0100147804            LLQDIPDGLTLEPDIHNALMKTMQRDCLVLQSFKIMDYSLLLAIHNLDEMEKEMAAKGTE
CG3682-RA               FMEQHPNGIFLEAETYAALIKTIQRDCTVLESFKIMDYSLLLGVHNLDVALKEKQSEQRK
                        ::::  :*: :: : . *: **::*** :*:********* :.:* :*    .       

ENSMUST00000045469      A-----------------------------QSKADEKRPVA-QKALYSTAMESIQGGAAR
ENST00000262964         A-----------------------------QSTSDEKRPVG-QKALYSTAMESIQGGAAR
SINFRUP00000160519      S-----------------------------QGDSDEKRPLAQQKALYSTAMESIQGGAAC
ENSMUST00000025800      L-----------------------------QNVPDAKRPGM-QKVLYSTAMESIQGPGKS
ENST00000327329         P-----------------------------QNVPDAKRTGM-QKVLYSTAMESIQGPGKS
SINFRUP00000158440      ---------------------------------CDSRKG---QKVLYSTALESIQGSMKD
ENST00000271663         ------------------------------QYSVDTRRPAP-QKALYSTAMESIQGEARR
ENST00000316494         ------------------------------QYSVDTRRPAP-QKALYSTAMESIQGEARR
ENST00000309390         ------------------------------QVSIDTQRLAP-QKALYSTAMEFIQGEARL
SINFRUP00000160931      V-----------------------------AGAADQRRPQG-QKSLYSTAIEAIEAEAGA
ci0100147804            VDVGYSNKLNQFIKLGTFAADLDSKYTHRRNSSSDYNSDDTPSTSVGYRAAQSVMDSTML
CG3682-RA               PLRAPLAEDSDVDADDPLDG-------DAATGISRNKSVNRQRLVAHSTAMESIQAE---
                                                            .            * : :      

ENSMUST00000045469      GEAIETD--DTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKALVHDGDTVSV
ENST00000262964         GEAIESD--DTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKALVHDGDTVSV
SINFRUP00000160519      GGSIDTD--DTMGGIPAVNGKGERLLLYIGIIDILQSYRLIKKLEHTWKALVHDGDTVSV
ENSMUST00000025800      ADGIIAENPDTMGGIPAKSHKGEKLLLFMGIIDILQSYRLMKKLEHSWKALVYDGDTVSV
ENST00000327329         GDGIITENPDTMGGIPAKSHRGEKLLLFMGIIDILQSYRLMKKLEHSWKALVYDGDTVSV
SINFRUP00000158440      PEPLGDD--DTFGGIPAK-YKDENLLIFLGIIDILQSYRLIKKMEHSWKALVHDGDTVSV
ENST00000271663         GGTMETD--DHMGGIPARNSKGERLLLYIGIIDILQSYRFVKKLEHSWKALVHDGDTVSV
ENST00000316494         GGTMETD--DHMGGIPARNSKGERLLLYIGIIDILQSYRFVKKLEHSWKALIHDGDTVSV
ENST00000309390         GDTMEAD--DHMGGIPAQNSKGERLLLYIGIIDILQSYTFLKKLEHSWKAVVHDGDAVSV
SINFRUP00000160931      G-STDTE--DKTGGIPAQNSKGERLLVYIGIIDILQSYRLVKKLEHSWKALVHDGDTVSV
ci0100147804            RTKYSKDLDHWSGGIPAKNGKGERLLVFCGVIDILQCYKWKKKMEHTWKSMIADGDSVSV
CG3682-RA               SEPIDDEEDVPPGGIPARSEKGERLLLYIGIIDILQSYRLKKKLEHTFKSIIHDGETVSV
                              :     *****   :.*.**:. *:*****.*   **:**::*::: **::***

ENSMUST00000045469      HRPSFYAERFFKFMSSTVFRKSSS-LKSSPSKK--GRG-ALLAVKPLGPTAAFSASQIPS
ENST00000262964         HRPSFYAERFFKFMSNTVFRKNSS-LKSSPSKK--GRGGALLAVKPLGPTAAFSASQIPS
SINFRUP00000160519      HRPGFYADRFLKFMSNTVFKKSSS-LKSSPSKK--GRA-SLSVPKCAGPGAAWSASQLHS
ENSMUST00000025800      HRPSFYADRFLKFMNSRVFKKIQA-LKASPSKK--RCN----SIAALKATSQEIVSSISQ
ENST00000327329         HRPSFYADRFLKFMNSRVFKKIQA-LKASPSKK--RCN----SIAALKATSQEIVSSISQ
SINFRUP00000158440      HRPSFYADRFLKFMGSTVFKKI--------------------------------------
ENST00000271663         HRPGFYAERFQRFMCNTVFKKIP--LKPSPSKK--FRS-GSSFSRRAGSSGNSCITYQPS
ENST00000316494         HRPGFYAEWFQRFMCNTVFKKIP--LKPSPSKK--LRS-GSSFSQRAGSSGNSCITYQPL
ENST00000309390         HRPGFYAERFQHFMCNAVFKKIP--LKPSPSKK--FRS-GLSFSLHTGSSGNSCITYQPL
SINFRUP00000160931      HRPGFYADRFEKFMCNVVFKKVP-------------------------------------
ci0100147804            HRPSFYCERFQKFMGDHVFKKSKF-ICTLPTAV--IIKYLEILIFHVLHPINLLISTK--
CG3682-RA               CRPSFYAQRFQNFMAKTVFRKIPSPLKHSPSKRKSLSKAIQRSIDSDNEVASRPVHASHS
                         **.**.: * .** . **:*    :                                  

ENSMUST00000045469      EREDVQYDLRG-ARSYPT-LEDEG-----RPDLLPCTPPSFEEATTASIATTLSS-TSLS
ENST00000262964         EREEAQYDLRG-ARSYPT-LEDEG-----RPDLLPCTPPSFEEATTASIATTLSS-TSLS
SINFRUP00000160519      DRDENIYDLRG-VRSFPT-LEDEG-----RPDLLPCTPPSFEEATTASIATTLSSTTSLS
ENSMUST00000025800      EWKDEKRDLLTEGQSFSS-LDEEALGSRHRPDLVPSTPSLFEAAS---LATTISS-SSLY
ENST00000327329         EWKDEKRDLLTEGQSFSS-LDEEALGSRHRPDLVPSTPSLFEAAS---LATTISS-SSLY
SINFRUP00000158440      ------------------------------------------------------------
ENST00000271663         VSGEHKAQVTTKAEVEPG-VHLGR------PDVLPQTPPLEEISEGSPIPDPSFSPLVGE
ENST00000316494         VSGEHKAQVTTKAEVEPG-VHLGC------PDVLPQTPPLEEISEGSPTPDPSFSPLVEE
ENST00000309390         VSEEHKSQV-IKVQVEPG-VHLGR------SDVLPQTS--ESTFGGNQ------------
SINFRUP00000160931      ------------------------------------------------------------
ci0100147804            ------------------------------------------------------------
CG3682-RA               HSSGKIHQPAKPPTTEPTPAGAAGGAERGATALGPATTSGASERAPPPVKQRTPAASNLK
                                                        :                           

ENSMUST00000045469      I-------PERSPSDTSEQPRYRRRTQSSGQDGRPQEEP-HAEDLQKITVQVEPVCGVG-
ENST00000262964         I-------PERSPSETSEQPRYRRRTQSSGQDGRPQEEPPAEEDLQQITVQVEPACSVEI
SINFRUP00000160519      I-------PERSPSDTAEHSRYR-------------------------------------
ENSMUST00000025800      V-------GEHYPHDRTTLYSNSKGLPSSST-----------------------------
ENST00000327329         V-------NEHYPHDRPTLYSNSKGLPSSST-----------------------------
SINFRUP00000158440      ------------------------------------------------------------
ENST00000271663         T-------LQMLTTSTTLEKLEVAESEFTH------------------------------
ENST00000316494         T-------LQMLTTS---------------------------------------------
ENST00000309390         ------------------------------------------------------------
SINFRUP00000160931      ------------------------------------------------------------
ci0100147804            ------------------------------------------------------------
CG3682-RA               TRVPPPVPPRGSPRRKDAQDRTTPGTTPSCSSTPPPAFDDISEDSSNKNSSSSIGRRSHH
                                                                                    

ENSMUST00000045469      VVPKEEGAGVEVPPCGASAAASVEID--AASQASEPASQASDEEDAPSTDIYFVS-----
ENST00000262964         VVPKEEDAGVEASPAGASAAVEVETASQASDEEGAPASQASDEEDAPATDIYFPTDERSW
SINFRUP00000160519      ------------------------------------------------------------
ENSMUST00000025800      -FTLEEGT---------------------IYLTAEPNTLDLQDD-ASVLDVYL-------
ENST00000327329         -FTLEEGT---------------------IYLTAEPNTLEVQDDNASVLDVYL-------
SINFRUP00000158440      ------------------------------------------------------------
ENST00000271663         ------------------------------------------------------------
ENST00000316494         ------------------------------------------------------------
ENST00000309390         ------------------------------------------------------------
SINFRUP00000160931      ------------------------------------------------------------
ci0100147804            ------------------------------------------------------------
CG3682-RA               HHHHHQQSQQHQQSYYLDRKMNIGPAYRGSYKEDIVSVSEVHLDTLLAVDTSSSSQYGSR
                                                                                    

ENSMUST00000045469      -------SPQDP--SSGPFGPL----------------
ENST00000262964         VYSPLHYSAQAPPASDGESDT-----------------
SINFRUP00000160519      --------------------------------------
ENSMUST00000025800      --------------------------------------
ENST00000327329         --------------------------------------
SINFRUP00000158440      --------------------------------------
ENST00000271663         --------------------------------------
ENST00000316494         --------------------------------------
ENST00000309390         --------------------------------------
SINFRUP00000160931      --------------------------------------
ci0100147804            --------------------------------------
CG3682-RA               GGLAWTPPASGEGSTPTWTEGTPSFTDSSSSGDLDQLT