Browse phylogenetic trees HUMAN

Human phylogenetic trees

For all human gene families, containing 2 to 10 members, we looked for orthologous genes in other organisms (mouse, fruitfly, pufferfish and other fish species). For these families, Neigbor Joining trees were drawn, which were used for relative dating of the duplication events within each gene family. Only those trees, supported with a bootstrap value greater than or equal to 700 (out of 1000), were retained. For these families, all proteins evolving significantly faster or slower than the others were removed in order to create linearized trees. When relevant branches are supported with a bootstrap value greater than or equal to 700 (out of 1000), these trees were used for absolute dating of the duplication events. In the table below, linearized trees are represented for those families giving both a significant and congruent relative and absolute date. The notation 1R/2R refers to the duplication event occurred before the divergence of Fugu (ray-finned fishes) and Human (land vertebrates). Sarcopterygian refers the duplication dates younger than the split between ray-finned fishes and land vertebrates.

TreeID	nr of human genes	Duplication nodes	Linearized tree
1	2	sarcopterygian	LT 1
3	2	1R/2R	LT 3
7	3	1R/2R	LT 7
12	6	sarcopterygian	LT 12
16	2	1R/2R	LT 16
17	2	1R/2R	LT 17
22	5	1R/2R 1R/2R	LT 22
26	2	1R/2R	LT 26
27	5	1R/2R	LT 27
28	3	1R/2R	LT 28
29	3	1R/2R	LT 29
30	2	sarcopterygian	LT 30
31	9	1R/2R	LT 31
49	3	1R/2R	LT 49
88	2	1R/2R	LT 88
90	2	1R/2R	LT 90
96	3	sarcopterygian	LT 96
100	2	1R/2R	LT 100
103	2	1R/2R	LT 103
110	8	1R/2R	LT 110
117	3	sarcopterygian	LT 117
124	7	sarcopterygian	LT 124
128	2	sarcopterygian	LT 128
129	3	sarcopterygian sarcopterygian	LT 129
133	2	1R/2R	LT 133
146	2	1R/2R	LT 146
148	4	1R/2R 1R/2R	LT 148
155	6	1R/2R	LT 155
167	5	sarcopterygian	LT 167
173	2	1R/2R	LT 173
178	4	sarcopterygian 1R/2R 1R/2R	LT 178
182	2	1R/2R	LT 182
184	3	1R/2R	LT 184
202	4	sarcopterygian 1R/2R	LT 202
204	2	1R/2R	LT 204
208	3	1R/2R	LT 208
219	2	1R/2R	LT 219
222	2	sarcopterygian	LT 222
230	2	sarcopterygian	LT 230
265	7	1R/2R	LT 265
292	4	sarcopterygian sarcopterygian	LT 292
296	2	1R/2R	LT 296
298	2	1R/2R	LT 298
299	2	1R/2R	LT 299
301	3	1R/2R 1R/2R	LT 301
303	4	sarcopterygian	LT 303
308	5	1R/2R 1R/2R	LT 308
311	2	1R/2R	LT 311
314	2	1R/2R	LT 314
318	2	sarcopterygian	LT 318
320	2	1R/2R	LT 320
330	2	1R/2R	LT 330
334	2	1R/2R	LT 334
339	2	1R/2R	LT 339
360	2	1R/2R	LT 360
368	2	1R/2R	LT 368
369	7	1R/2R	LT 369
376	4	1R/2R	LT 376
393	4	sarcopterygian 1R/2R	LT 393
404	2	1R/2R	LT 404
406	2	sarcopterygian	LT 406
410	2	sarcopterygian	LT 410
415	2	1R/2R	LT 415
425	5	1R/2R	LT 425
435	5	sarcopterygian sarcopterygian 1R/2R	LT 435
436	6	1R/2R 1R/2R	LT 436
439	4	1R/2R 1R/2R	LT 439
440	3	1R/2R	LT 440
441	3	1R/2R	LT 441
444	4	1R/2R	LT 444
465	2	sarcopterygian	LT 465
470	6	1R/2R 1R/2R	LT 470
475	2	sarcopterygian	LT 475
477	2	1R/2R	LT 477
482	2	1R/2R	LT 482
488	5	sarcopterygian 1R/2R	LT 488
495	2	sarcopterygian	LT 495
498	2	1R/2R	LT 498
508	4	1R/2R 1R/2R	LT 508
511	4	sarcopterygian 1R/2R	LT 511
513	4	sarcopterygian	LT 513
521	2	1R/2R	LT 521
522	3	sarcopterygian	LT 522
523	2	1R/2R	LT 523
529	3	1R/2R	LT 529
534	7	1R/2R	LT 534
543	2	1R/2R	LT 543
556	4	1R/2R	LT 556
558	6	1R/2R	LT 558
574	2	1R/2R	LT 574
588	2	1R/2R	LT 588
592	2	1R/2R	LT 592
595	4	1R/2R	LT 595
599	2	1R/2R	LT 599
606	4	sarcopterygian 1R/2R	LT 606
607	2	1R/2R	LT 607
622	2	1R/2R	LT 622
635	3	1R/2R	LT 635
667	2	1R/2R	LT 667
668	2	1R/2R	LT 668
669	2	1R/2R	LT 669
672	2	1R/2R	LT 672
677	3	1R/2R	LT 677
678	3	1R/2R	LT 678
692	3	1R/2R	LT 692
699	3	1R/2R 1R/2R	LT 699
700	2	1R/2R	LT 700
706	3	1R/2R	LT 706
710	2	1R/2R	LT 710
717	2	1R/2R	LT 717
728	2	1R/2R	LT 728
743	2	1R/2R	LT 743
758	3	1R/2R	LT 758
763	3	1R/2R	LT 763
768	2	1R/2R	LT 768
784	2	1R/2R	LT 784
785	2	sarcopterygian	LT 785
788	2	1R/2R	LT 788
794	2	1R/2R	LT 794
823	2	1R/2R	LT 823
830	3	1R/2R 1R/2R	LT 830
835	2	1R/2R	LT 835
836	2	1R/2R	LT 836
846	2	sarcopterygian	LT 846
868	2	sarcopterygian	LT 868
869	2	sarcopterygian	LT 869
872	2	1R/2R	LT 872
888	2	sarcopterygian	LT 888
897	2	1R/2R	LT 897
898	2	1R/2R	LT 898
917	2	1R/2R	LT 917
920	2	1R/2R	LT 920
931	5	1R/2R	LT 931
935	2	1R/2R	LT 935
945	3	1R/2R	LT 945
946	2	1R/2R	LT 946
948	7	sarcopterygian	LT 948
972	2	1R/2R	LT 972
979	2	1R/2R	LT 979
988	3	sarcopterygian	LT 988
989	2	1R/2R	LT 989
993	3	1R/2R	LT 993
1007	2	sarcopterygian	LT 1007
1009	2	1R/2R	LT 1009
1010	2	1R/2R	LT 1010
1012	2	1R/2R	LT 1012
1019	2	sarcopterygian	LT 1019
1020	2	1R/2R	LT 1020
1021	2	1R/2R	LT 1021
1025	2	1R/2R	LT 1025
1032	2	sarcopterygian	LT 1032
1034	3	1R/2R	LT 1034
1038	4	1R/2R	LT 1038
1046	2	1R/2R	LT 1046
1063	3	sarcopterygian	LT 1063
1071	2	1R/2R	LT 1071
1075	2	1R/2R	LT 1075
1081	2	sarcopterygian	LT 1081
1087	2	1R/2R	LT 1087
1090	2	1R/2R	LT 1090
1092	2	1R/2R	LT 1092
1094	2	1R/2R	LT 1094
1095	4	1R/2R	LT 1095
1096	4	1R/2R	LT 1096
1109	2	1R/2R	LT 1109
1116	2	sarcopterygian	LT 1116
1122	2	1R/2R	LT 1122
1123	2	1R/2R	LT 1123
1126	2	1R/2R	LT 1126
1138	5	1R/2R	LT 1138
1141	2	1R/2R	LT 1141
1149	2	1R/2R	LT 1149
1156	2	sarcopterygian	LT 1156
1173	2	1R/2R	LT 1173
1196	2	1R/2R	LT 1196
1207	3	1R/2R	LT 1207
1208	2	1R/2R	LT 1208
1210	3	sarcopterygian	LT 1210
1224	2	1R/2R	LT 1224
1225	3	1R/2R	LT 1225
1234	2	1R/2R	LT 1234
1240	3	1R/2R 1R/2R	LT 1240
1255	2	1R/2R	LT 1255
1261	3	sarcopterygian	LT 1261
1280	6	1R/2R	LT 1280
1284	3	1R/2R	LT 1284
1291	2	1R/2R	LT 1291
1301	2	1R/2R	LT 1301
1303	2	1R/2R	LT 1303
1309	2	1R/2R	LT 1309
1316	2	1R/2R	LT 1316
1317	2	sarcopterygian	LT 1317
1331	2	1R/2R	LT 1331
1338	2	1R/2R	LT 1338
1343	2	1R/2R	LT 1343
1351	2	1R/2R	LT 1351
1353	2	sarcopterygian	LT 1353
1360	2	sarcopterygian	LT 1360
1362	3	1R/2R	LT 1362
1366	2	1R/2R	LT 1366
1376	2	sarcopterygian	LT 1376
1381	3	sarcopterygian	LT 1381
1393	3	sarcopterygian	LT 1393
1406	2	sarcopterygian	LT 1406
1421	3	1R/2R	LT 1421
1423	4	1R/2R	LT 1423
1437	3	1R/2R	LT 1437
1442	2	1R/2R	LT 1442
1443	2	1R/2R	LT 1443
1445	2	sarcopterygian	LT 1445
1453	2	1R/2R	LT 1453
1456	2	1R/2R	LT 1456
1457	2	sarcopterygian	LT 1457
1460	2	1R/2R	LT 1460
1468	2	sarcopterygian	LT 1468
1470	3	1R/2R 1R/2R	LT 1470
1476	2	1R/2R	LT 1476
1477	2	1R/2R	LT 1477
1488	2	sarcopterygian	LT 1488
1493	2	1R/2R	LT 1493
1494	2	1R/2R	LT 1494
1508	2	1R/2R	LT 1508
1513	2	1R/2R	LT 1513
1522	2	sarcopterygian	LT 1522
1533	3	1R/2R	LT 1533
1538	2	sarcopterygian	LT 1538
1542	2	sarcopterygian	LT 1542
1547	6	1R/2R	LT 1547
1550	4	sarcopterygian	LT 1550
1551	4	1R/2R	LT 1551
1563	2	1R/2R	LT 1563
1572	3	1R/2R	LT 1572
1610	2	1R/2R	LT 1610
1621	2	1R/2R	LT 1621
1627	2	sarcopterygian	LT 1627
1628	3	1R/2R	LT 1628
1630	4	sarcopterygian	LT 1630
1641	2	sarcopterygian	LT 1641
1650	3	1R/2R 1R/2R	LT 1650
1657	2	1R/2R	LT 1657
1679	3	1R/2R	LT 1679
1680	3	sarcopterygian 1R/2R	LT 1680
1682	2	sarcopterygian	LT 1682
1696	2	1R/2R	LT 1696
1703	3	sarcopterygian	LT 1703
1705	2	1R/2R	LT 1705
1709	2	sarcopterygian	LT 1709
1729	5	sarcopterygian sarcopterygian	LT 1729
1740	2	1R/2R	LT 1740
1746	2	1R/2R	LT 1746
1747	2	1R/2R	LT 1747
1754	2	sarcopterygian	LT 1754
1760	2	1R/2R	LT 1760
1763	3	1R/2R 1R/2R	LT 1763
1776	2	1R/2R	LT 1776
1777	3	1R/2R	LT 1777
1778	3	1R/2R 1R/2R	LT 1778
1785	2	1R/2R	LT 1785
1787	2	1R/2R	LT 1787
1809	2	1R/2R	LT 1809
1810	3	1R/2R	LT 1810
1813	3	1R/2R	LT 1813
1822	2	1R/2R	LT 1822
1829	2	1R/2R	LT 1829
1836	3	1R/2R	LT 1836
1842	2	1R/2R	LT 1842
1845	2	1R/2R	LT 1845
1872	2	1R/2R	LT 1872
1885	2	1R/2R	LT 1885
1890	2	1R/2R	LT 1890
1894	3	1R/2R 1R/2R	LT 1894
1897	3	1R/2R	LT 1897
1928	3	1R/2R	LT 1928
1939	2	1R/2R	LT 1939
1943	2	1R/2R	LT 1943
1948	4	1R/2R	LT 1948
1955	3	1R/2R	LT 1955
1974	2	1R/2R	LT 1974
1982	2	1R/2R	LT 1982
1989	2	1R/2R	LT 1989
1998	2	sarcopterygian	LT 1998
2007	2	1R/2R	LT 2007
2011	2	1R/2R	LT 2011
2014	2	1R/2R	LT 2014
2017	2	sarcopterygian	LT 2017
2020	2	1R/2R	LT 2020
2047	4	sarcopterygian	LT 2047
2051	2	1R/2R	LT 2051
2099	2	1R/2R	LT 2099
2112	3	1R/2R 1R/2R	LT 2112
2130	5	sarcopterygian sarcopterygian sarcopterygian 1R/2R	LT 2130
2134	2	1R/2R	LT 2134
2141	2	1R/2R	LT 2141
2146	3	1R/2R 1R/2R	LT 2146
2163	2	sarcopterygian	LT 2163
2175	3	1R/2R	LT 2175
2183	2	1R/2R	LT 2183
2188	2	1R/2R	LT 2188
2192	2	1R/2R	LT 2192
2198	3	1R/2R	LT 2198
2222	2	1R/2R	LT 2222
2230	2	1R/2R	LT 2230
2250	2	1R/2R	LT 2250
2256	2	sarcopterygian	LT 2256
2269	2	1R/2R	LT 2269
2280	2	1R/2R	LT 2280
2282	2	1R/2R	LT 2282
2287	2	sarcopterygian	LT 2287
2305	2	1R/2R	LT 2305
2316	2	1R/2R	LT 2316
2317	2	1R/2R	LT 2317
2330	2	sarcopterygian	LT 2330
2348	2	sarcopterygian	LT 2348
2352	2	1R/2R	LT 2352
2360	2	1R/2R	LT 2360
2375	2	1R/2R	LT 2375
2383	2	sarcopterygian	LT 2383
2396	2	1R/2R	LT 2396
2405	2	1R/2R	LT 2405
2418	2	1R/2R	LT 2418
2419	2	1R/2R	LT 2419
2450	2	1R/2R	LT 2450
2452	2	sarcopterygian	LT 2452
2457	2	sarcopterygian	LT 2457
2461	2	1R/2R	LT 2461
2464	2	1R/2R	LT 2464
2500	2	1R/2R	LT 2500
2504	2	1R/2R	LT 2504
2507	2	1R/2R	LT 2507
2535	2	1R/2R	LT 2535
2549	2	1R/2R	LT 2549
2557	2	1R/2R	LT 2557
2591	2	1R/2R	LT 2591
2595	3	1R/2R	LT 2595
2604	2	1R/2R	LT 2604
2617	3	sarcopterygian	LT 2617
2668	2	1R/2R	LT 2668